- Fungal Biology and Applications
- Protein Hydrolysis and Bioactive Peptides
- Phytochemicals and Antioxidant Activities
- Human Health and Disease
- Exercise and Physiological Responses
- Cardiomyopathy and Myosin Studies
- Cardiovascular Effects of Exercise
- Meat and Animal Product Quality
- Gout, Hyperuricemia, Uric Acid
- Bone Tissue Engineering Materials
- Physical Education and Training Studies
- Bee Products Chemical Analysis
- Engineering Technology and Methodologies
- Animal Nutrition and Physiology
- Curcumin's Biomedical Applications
- Tea Polyphenols and Effects
- Phytochemistry and Biological Activities
- Body Composition Measurement Techniques
- Nutrition, Genetics, and Disease
- Plant biochemistry and biosynthesis
- Advanced Photocatalysis Techniques
- Titanium Alloys Microstructure and Properties
- Polymer Synthesis and Characterization
- Medicinal Plants and Bioactive Compounds
- Probiotics and Fermented Foods
North-Caucasus Federal University
2015-2025
Institute of Molecular Pathology and Pathomorphology
2022
Stavropol State Medical University
2022
Moscow Region State University
2017
In food biotechnology, Pleurotus ostreatus is of great interest as a source natural antioxidants and angiotensin-converting enzyme (ACE) inhibitors. However, research in this area has not yet been completed. The effect various drying methods on the structural properties rehydration capacity mushrooms was investigated paper. content secondary metabolites, peptide profile, antioxidative ACE inhibitory activity dry were vitro, simulating process gastrointestinal digestion. X-ray microtomography...
Chlorophytum genus has been extensively studied due to its diverse biological activities. We evaluated the methanolic extract of leaves comosum (Green type) (Thunb.) Jacques, species that is less compared C. borivilianum. The aim was identify phytoconstituents and properties different fractions. Water fraction analyzed with matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry. Nineteen compounds belonging chemical classes were identified in Jacques. In...
Finding new, safe strategies to prevent and control rheumatoid arthritis is an urgent task. Bioactive peptides peptide-rich protein hydrolyzate represent a new trend in the development of functional foods nutraceuticals. The resulting tissue chicken embryo (CETH) has been evaluated for acute toxicity tested against chronic induced by Freund's full adjuvant (modified Mycobacterium butyricum) rats. antiarthritic effect CETH was studied on 28th day experiment after 2 weeks oral administration...
Biocompatibility is one of the most important characteristics materials for implantation. It has been scientifically confirmed that physical and chemical properties surface metal implants or their elements can have an impact on clinical safety. The structure material (porosity, smoothness, geometry) influence its incorporation into surrounding tissues. This requires conducting experiments with a longer contact interval tested under in vivo conditions.
Mushroom powders, as functional food ingredients, have attracted much attention in recent years. In the present study, four drying methods, i.e., freeze (FD), hot air (HAD), microwave (MWD), and sun (SD), were investigated to determine effects on structure lipid profile of mushroom powder. The morphology powder was studied by using X-ray microtomography. surface particles scanning electron microscopy. identification lipophilic components carried out gas chromatography a extract obtained...
The aim of the investigation was to study level amylolytic activity and microtomographic index synovial fluid density as well substantiate their clinical pathogenetic significance by identifying correlations with known informative indicators reflecting characteristic features pathological process in various joint diseases.Samples from 95 patients pathologies at stage disease progression characterized copious effusion into articular cavities have been examined. Synovial samples obtained knee...
X-ray contrast techniques were tested on the chick embryos in early periods of embryogenesis. For stain, reagents with radiopacity various concentrations used: silver proteinate, eosin, Lugol’s solution (I2KI), phosphomolybdic acid and phosphotungstic under heating at 25 °C 40 exposure for 24 48 h. The use eosin I2KI embryo period embryogenesis did not make it possible to obtain microtomographic results that provide reliable microstructural analysis. most optimal effective method staining...
Relevance . The positive aspects of disinfecting ozonation hatching eggs allow us to expect successful application the method not only in large but also small-scale farms, as well for experimental and industrial purposes laboratories bio-enterprises related technological process based on incubation a small number eggs. This determines importance expanding range ozonizers due numerous portable devices. There are no clear recommendations these devices this causes need search most effective...
Oyster mushroom (Pleurotus ostreatus L.) is a valuable food product. It possesses an antiatherogenic potential, which has to be preserved during processing. The paper features the production of oyster sublimates. focuses on such pre-treatment conditions as grinding, disinfection, and cryostabilisation, their effect potential mushrooms. A set in vitro experiments was performed measure levels lovastatin antioxidant, catalase, anti-inflammatory, thrombolytic properties. Various proved produce...
The aim of this research was to study the influence two drying methods: freeze-drying sublimation and dry-air on selected nutritional properties hypolipidemic potential fruiting bodies oyster mushroom (Pleurotus ostreatus). criteria for evaluation food were color, morphological structure, regidratation capacity, total level soluble proteins, fats, polysaccharides, free amino acids monosaccharides. Lipid-lowering evaluated by concentration lovastatin antioxidant activity. It has been...
Relevance . The chicken embryo model is ideal for studying the development of heart, which first functioning organ in embryogenesis. Particular attention drawn to embryonic period, when heart both and forming, small deviations this process can lead developmental anomalies. current lack results accurate measurements morphology a requires high-quality visualization, complexity determined by dynamic changes size complex spatial details organ. Threedimensional imaging methods are indispensable...
In this investigation, we revealed that application of the biostimulating tissue preparation based on chicken embryos (“STEMB”) at experimental hepatorenal syndrome showed improvement morphofunctional parameters a liver. Under influence biostimulator relative mass liver considerably decreased and biochemical markers condition (total bilirubin, ALT, AST) returned to normal. Besides, under “STEMB” tendency normalization mitotic, apoptotic binuclear cells index tissues considerable decrease in...
Relevance. Early diagnosis of chronic overstress among athletes remains an important problem for coaches and specialists in the field sports physiology medicine. The goal is to study animal model dynamics autoimmune response physical activity different duration intensity establish prospects method determining autoantibodies cardiomyocyte proteins as indicator morphofunctional state heart conditions adaptation muscle loads. Materials Methods. was conducted male white rats. Animals were...
Assessing the embryotoxicity and teratogenicity of various substances processes is crucial due to their complexity resource intensity. The chicken embryo (CE) serves an ideal model for simulating first months mammalian embryonic development. This makes CE a reliable testing teratogenic effects, particularly in relation nervous system (NS), which experiences developmental abnormalities second frequency only cardiovascular disorders. Microcomputed tomography (μCT) promising method studying...
The spectral properties and thermal stability of cyclodextrins:curcuminoids nanocomplexes were characterized by the use methods IR spectroscopy analysis. changes in activation energy destruction curcuminoids during formation calculated. In model system for reduction radical cation ABTS˙+, IC50 values determined with β-cyclodextrin (Curc:β-CD) 2-hydroxypropyl-beta-cyclodextrin (Curc:HP-β-CD), obtained co-evaporation lyophilization at a ratio 1:2, which 1.076 g/L 0.161 g/L, respectively. Using...
Abstract A comparative analysis of mass–volume characteristics structural and morphological components hen eggs before incubation on the fifth (HH25–HH27) 10th (HH36) days was carried out. During incubation, egg weight decreased by 9.25% (10 days), mainly due to a decrease in albumen (35.8%). The ratio lipid‐soluble fraction (LSF) water‐soluble (WSF) mixed yolk did not change significantly. total amount solids substances practically does during incubation. Antiradical activity increased...
Finding new, safe strategies to prevent and control rheumatoid arthritis is an urgent task. Of particular interest in this regard are bioactive peptides peptide-rich protein hydrolyzates, which represent a new trend the development of functional foods nutraceuticals. The resulting tissue hydrolyzate chicken embryo (CETH) has been evaluated for acute toxicity tested against chronic induced by Freund's full adjuvant rats. anti-arthritic effect CETH was studied on 28th day experiment after two...
В настоящее время актуальной является проблема дисбиозов, для коррекции которых предпочтительно применение пребиотиков.В качестве потенциального сырьевого объекта получения пребиотика, за счет широкого спектра биохимических составляющих микробного происхождения, рассмотрена зооглея симбионта Medusomyces gysevii (чайный гриб).Проводилось изучение влияния этой субстанции на микробиоциноз кишечника крыс.Полученные результаты свидетельствуют о том, что при пероральном поступлении...
Relevance. In conditions of ever-increasing volume training loads, the frequency cases chronic physical overstrain (CPO) among athletes is increasing. It determines importance early diagnosis formed pathology cardiovascular system in order to prevent its further development. The aim study was dynamics autoantibodies cardiomyocyte proteins using an experimental model CPO and determine prospects a laboratory method for determination pathomorphological changes heart. Materials Methods....
The present study was conducted to evaluate the effect of biologically active substances from Medusomyces gisevii zoogloea (MG zoogloeas) on intestine microbiocenosis white rats during experimental antibioticassociated dysbiosis. intestinal dysbiosis induced by gentamicin sulfate in dose 10 mg/ rat twice a day for days all rats. Animals control group received standard diet recommended Institute Nutrition, animals 120 mg substance MG zoogloea/rat every experiment, addition usual diet. After...
The search for new strategies the prevention and control of osteoporosis is an urgent task. Functional foodstuffs their components are particular interest in this regard. aim was to study effect bread enriched with protein, dietary fiber, calcium, iron iodine on state bone tissue rats a model postmenopausal osteoporosis. Material methods. experiment performed sexually mature female Wistar divided into groups: K - (sham-operated rats, not ovariectomized); О30 (animals were sacrificed 30 days...