A5017120099- RNA and protein synthesis mechanisms
- Human Health and Disease
- Food Industry and Aquatic Biology
- Protein Hydrolysis and Bioactive Peptides
- Fungal Biology and Applications
- RNA modifications and cancer
- Engineering Technology and Methodologies
- Cardiovascular Effects of Exercise
- Cardiomyopathy and Myosin Studies
- Phytochemicals and Antioxidant Activities
- Exercise and Physiological Responses
- Curcumin's Biomedical Applications
- Bee Products Chemical Analysis
- Meat and Animal Product Quality
- Microencapsulation and Drying Processes
- Plant Growth Enhancement Techniques
- Seed Germination and Physiology
- Endodontics and Root Canal Treatments
- Animal Nutrition and Physiology
- Nanoparticles: synthesis and applications
- Stress Responses and Cortisol
- Enzyme Production and Characterization
- Antimicrobial Peptides and Activities
- Liver Disease Diagnosis and Treatment
- Probiotics and Fermented Foods
North-Caucasus Federal University
2016-2025
Penza State University
2022
Office of Technology Transfer
2022
Center for Innovation
2022
Institute of Molecular Pathology and Pathomorphology
2022
Stavropol State Medical University
2022
Moscow Region State University
2017
In food biotechnology, Pleurotus ostreatus is of great interest as a source natural antioxidants and angiotensin-converting enzyme (ACE) inhibitors. However, research in this area has not yet been completed. The effect various drying methods on the structural properties rehydration capacity mushrooms was investigated paper. content secondary metabolites, peptide profile, antioxidative ACE inhibitory activity dry were vitro, simulating process gastrointestinal digestion. X-ray microtomography...
In this work, we obtained silver nanoparticles stabilized with polyvinylpyrrolidone, ranging in size from 70 to 110 nm, which exhibits good crystallinity and anisotropic structure. For the first time, studied influence of molar ratio between peroxide on oxidation process determined regularities by analyzing changes absorption spectra. Our results showed that at ratios Ag:H2O2 = 1:1 1:5, dependences intensity, position half-width band plasmon resonance are rectilinear. vivo studies have shown...
Abstract The purpose of this work was to study the effect selenium nanoparticles (Se NPs) on biological and morphofunctional parameters barley seeds ( Hordéum vulgáre L.) We used L. with reduced characteristics. For experiment, Se NPs were synthesized stabilized didecyldimethylammonium chloride. It found that have a spherical shape diameter about 50 nm. According dynamic light scattering data, average hydrodynamic radius particles 28 ± 8 is observed positive ζ-potential (+ 27.3 mV). we...
The study focuses on in vitro tracing of some fundamental changes that emerge teeth at the initial stage caries development using multiple approaches. research was conducted a mostly sound maxillary molar tooth but with clearly visible natural proximal white spot lesion (WSL). Values mineral density, reduced Young's modulus, indentation hardness and creep as well molecular composition surface microstructure WSL bordering dentine area were studied. results obtained compared to those enamel...
Chlorophytum genus has been extensively studied due to its diverse biological activities. We evaluated the methanolic extract of leaves comosum (Green type) (Thunb.) Jacques, species that is less compared C. borivilianum. The aim was identify phytoconstituents and properties different fractions. Water fraction analyzed with matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry. Nineteen compounds belonging chemical classes were identified in Jacques. In...
Finding new, safe strategies to prevent and control rheumatoid arthritis is an urgent task. Bioactive peptides peptide-rich protein hydrolyzate represent a new trend in the development of functional foods nutraceuticals. The resulting tissue chicken embryo (CETH) has been evaluated for acute toxicity tested against chronic induced by Freund's full adjuvant (modified Mycobacterium butyricum) rats. antiarthritic effect CETH was studied on 28th day experiment after 2 weeks oral administration...
Biocompatibility is one of the most important characteristics materials for implantation. It has been scientifically confirmed that physical and chemical properties surface metal implants or their elements can have an impact on clinical safety. The structure material (porosity, smoothness, geometry) influence its incorporation into surrounding tissues. This requires conducting experiments with a longer contact interval tested under in vivo conditions.
The SARS-CoV-2 delta variant (B.1.617.2) appeared for the first time in December 2020 and later spread worldwide. Currently available vaccines are not so efficacious curbing viral pathogenesis of strain COVID; therefore, development a safe effective vaccine is required. In present study, we envisaged molecular patterns structural genes' spike, nucleoprotein, membrane, envelope variant. study was based on determining compositional features, dinucleotide odds ratio, synonymous codon usage,...
Mushroom powders, as functional food ingredients, have attracted much attention in recent years. In the present study, four drying methods, i.e., freeze (FD), hot air (HAD), microwave (MWD), and sun (SD), were investigated to determine effects on structure lipid profile of mushroom powder. The morphology powder was studied by using X-ray microtomography. surface particles scanning electron microscopy. identification lipophilic components carried out gas chromatography a extract obtained...
Hepatitis C virus (HCV) is enveloped RNA virus, encoding for a polyprotein that processed by cellular proteases. The responsible liver cirrhosis, allograft rejection, and human hepatocellular carcinoma. Based on studies including compositional analysis, odds ratio parity skew relative synonymous codon usage, bias, protein properties, it was evident usage bias in HCV dependent upon the nucleotide composition. Codon context analysis revealed CTC-CTG as preferred pair. While CGA CGT codons were...
This study aimed to synthesize, characterize, and evaluate the effect of cocamidopropyl betaine-stabilized MnO2 nanoparticles (NPs) on germination development pea seedlings. The synthesized NPs manifested as aggregates ranging from 50–600 nm, comprising spherical particles sized between 19 50 nm. These exhibited partial crystallization, indicated by peaks at 2θ = 25.37, 37.62, 41.18, 49.41, 61.45, 65.79°, characteristic with a tetragonal crystal lattice I4/m spatial group. Quantum chemical...
The aim of the investigation was to study level amylolytic activity and microtomographic index synovial fluid density as well substantiate their clinical pathogenetic significance by identifying correlations with known informative indicators reflecting characteristic features pathological process in various joint diseases.Samples from 95 patients pathologies at stage disease progression characterized copious effusion into articular cavities have been examined. Synovial samples obtained knee...
X-ray contrast techniques were tested on the chick embryos in early periods of embryogenesis. For stain, reagents with radiopacity various concentrations used: silver proteinate, eosin, Lugol’s solution (I2KI), phosphomolybdic acid and phosphotungstic under heating at 25 °C 40 exposure for 24 48 h. The use eosin I2KI embryo period embryogenesis did not make it possible to obtain microtomographic results that provide reliable microstructural analysis. most optimal effective method staining...
Dry milk molasses with lactulose is a product of processing by-products in the lactose production. Its use fermented drinks technology offers new opportunities to expand food range prebiotic effect. The research aims at studying possibility dry yogurt production technology, as well distinguish ultrasonic treatment impact on quality characteristics finished products. authors revealed that an amount 3 % total mass mixture enables intensify fermentation process and obtain drink high consumer...
Relevance . The positive aspects of disinfecting ozonation hatching eggs allow us to expect successful application the method not only in large but also small-scale farms, as well for experimental and industrial purposes laboratories bio-enterprises related technological process based on incubation a small number eggs. This determines importance expanding range ozonizers due numerous portable devices. There are no clear recommendations these devices this causes need search most effective...
The overexpression of SARS-CoV-2 primary receptors and co-receptors (ACE2, TMPRSS2, FURIN, CD147) enhance the likeliness infection. genes for same are overexpressed in periodontal tissues periodontitis patients. On other hand, BMAL1 is recognized to play a crucial role regulating pulmonary inflammation enhancing susceptibility viral Silenced disrupts circadian transcriptional regulations, enhances vulnerability infections, may trigger further production TNF-α pro-inflammatory cytokines that...
Oyster mushroom (Pleurotus ostreatus L.) is a valuable food product. It possesses an antiatherogenic potential, which has to be preserved during processing. The paper features the production of oyster sublimates. focuses on such pre-treatment conditions as grinding, disinfection, and cryostabilisation, their effect potential mushrooms. A set in vitro experiments was performed measure levels lovastatin antioxidant, catalase, anti-inflammatory, thrombolytic properties. Various proved produce...
The aim of this research was to study the influence two drying methods: freeze-drying sublimation and dry-air on selected nutritional properties hypolipidemic potential fruiting bodies oyster mushroom (Pleurotus ostreatus). criteria for evaluation food were color, morphological structure, regidratation capacity, total level soluble proteins, fats, polysaccharides, free amino acids monosaccharides. Lipid-lowering evaluated by concentration lovastatin antioxidant activity. It has been...
Introduction: Apoptosis and autophagy are the two fundamental processes involved in maintaining homeostasis, a common stimulus may initiate processes. Autophagy has been implicated various diseases, including viral infections. Genetic manipulations leading to altered gene expression might be strategy check virus infection. Aim: Determination of molecular patterns, relative synonymous codon usage, preference, bias, pair rare codons so that genetic manipulation genes done curb Method: Using...
Human bocavirus (HBoV), of the genus Bocaparvovirus, is a small, non-enveloped linear single-stranded DNA virus Parvoviridae family. The known to cause severe life-threatening respiratory tract infections in pediatric patients. Considering its deleterious impacts on respiratory, gastrointestinal, and hematological health, we prompted investigate codon usage patterns, parity, neutrality, Nc-GC3 analysis, gene expression, Intrinsic bias index (ICDI), Codon (CBI), Relative deoptimization...