Tilman Fritsch

ORCID: 0000-0003-1494-0768
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About
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Research Areas
  • Genetics, Aging, and Longevity in Model Organisms
  • Medicinal Plants and Bioactive Compounds
  • Hearing, Cochlea, Tinnitus, Genetics
  • Dental Implant Techniques and Outcomes
  • Mesenchymal stem cell research
  • Pharmacological Effects of Medicinal Plants
  • Genomics, phytochemicals, and oxidative stress
  • Periodontal Regeneration and Treatments
  • Vestibular and auditory disorders
  • Cleft Lip and Palate Research
  • Bone Metabolism and Diseases
  • Spaceflight effects on biology
  • Dental Trauma and Treatments
  • Protein Hydrolysis and Bioactive Peptides
  • Effects of Radiation Exposure
  • Antioxidant Activity and Oxidative Stress
  • Bone and Dental Protein Studies
  • Trace Elements in Health
  • Curcumin's Biomedical Applications
  • Plant Stress Responses and Tolerance
  • Biochemical effects in animals
  • Antioxidants, Aging, Portulaca oleracea
  • Healthcare and Venom Research
  • Biochemical and Structural Characterization
  • Food Science and Nutritional Studies

Supply Chain Competence Center (Germany)
2022

Stavropol State Medical University
2020-2021

Sechenov University
2020

Finding new, safe strategies to prevent and control rheumatoid arthritis is an urgent task. Bioactive peptides peptide-rich protein hydrolyzate represent a new trend in the development of functional foods nutraceuticals. The resulting tissue chicken embryo (CETH) has been evaluated for acute toxicity tested against chronic induced by Freund's full adjuvant (modified Mycobacterium butyricum) rats. antiarthritic effect CETH was studied on 28th day experiment after 2 weeks oral administration...

10.1002/fsn3.2529 article EN Food Science & Nutrition 2021-08-18

Traumatic brain injury (TBI) is described as a structural damage or physiological disturbance of function that occurs after trauma and causes disability death in people all ages. New treatment targets for TBI are being explored because current medicines frequently ineffectual poorly tolerated. There increasing evidence following TBI, there widespread changes autophagy-related proteins both experimental clinical settings. The study investigated if Boswellia Sacra Gum Resin (BSR) (500 mg/kg)...

10.3389/fphys.2023.1320960 article EN cc-by Frontiers in Physiology 2024-01-05

Background Several epidemiological studies and intervention trials have demonstrated that grapes blueberries, which are rich in flavanols, can lower the risk of cardiovascular disease. However, mechanisms action these compounds remain unclear due to their low bioavailability.

10.1080/19390211.2024.2446186 article EN Journal of Dietary Supplements 2025-01-10

Flavan-3-ols (FLs), astringent polyphenols, are known to have low bioavailability and induce excessive sympathetic nervous system activation. This study aimed compare the effects of FLs on brown, subcutaneous, visceral adipose tissue in mice. C57BL/6J male mice fed a standard or high-fat diet were given water 50 mg/kg FL orally by gavage for 2 weeks. Excised inguinal, epididymal fat tissues prepared frozen sectioning. After hematoxylin eosin (HE) staining, administration each observed,...

10.1515/med-2025-1152 article EN cc-by Open Medicine 2025-01-01

Background: Meniere's disease (MD) is a cochlear neurodegenerative disease. Hearing loss appears to be triggered by oxidative stress in the ganglion neurons of inner ear. Objective: Here, we confirm variation markers and inflammation patients with Meniere hypothesize that chronic treatment Coriolus mushroom helps response acts on α-synuclein NF-kB-mediated inflammatory processes. Methods: Markers were evaluated MD or without for 3 6 months. Results: had small increase Nrf2, HO-1, γ-GC,...

10.2174/1570159x22666231206153936 article EN Current Neuropharmacology 2023-12-11

AbstractIn this work we examined the contents of 14 polyphenols in white lupin (Lupinus albus L.) samples cultivated Southern Italy by optimisation and validation a LC-HRMS method. The method showed linearity results r2 > 0.989 recovery values between 71 119% for very wide range concentrations. Ellagic acid was most abundant polyphenol, with mean concentrations 16271.86 ± 19798.53 μg/Kg, followed apigenin (2749.51 889.95 μg/Kg). A significant variability ellagic found areas cultivation (p <...

10.1080/14786419.2023.2245535 article EN Natural Product Research 2023-09-07

ИСПОЛЬзОВАНИЕ ЭКТОМЕзЕНХИМАЛЬНЫХ СТВОЛОВЫХ КЛЕТОК ДЛЯ ПОТЕНЦИРОВАНИЯ РЕГЕНЕРАЦИИ АЛЬВЕОЛЯРНОй КОСТИ НА

10.14300/mnnc.2016.11034 article RU Medical news of the North Caucasus 2016-01-01

ЭКСпЕРИмЕНТАЛЬНАЯ мОДЕЛЬ ОСТЕОпОРОЗА АЛЬВЕОЛЯРНЫХ КОСТЕЙ У ОВЕЦ ДЛЯ СРАВНИТЕЛЬНОГО ИССЛЕДОВАНИЯ ОСТЕОГЕННЫХ СВОЙСТВ мАТЕРИАЛОВ С. В. Сирак 1 , Е. Щетинин Д. Бобрышев Т. Фрич 2 Б. Гизенхаген 3 Г .Г. петросян Н. Диденко Р. Г. Романенко В

10.14300/mnnc.2017.12091 article RU Medical news of the North Caucasus 2017-01-01

Hormesis is a biological phenomenon where exposure to low dose of stressor or toxin induces beneficial adaptive response, whereas higher doses may have detrimental effects. The concept hormesis being increasingly appreciated not only in toxicology and pharmacology, but also nutrition, clinical medicine, situations involving everyday life. an response cells organisms moderate intermittent stressful stimulation. Following such stimulation, the organism must respond, it has make choice: either...

10.1016/j.tma.2024.08.001 article EN cc-by-nc-nd Translational Medicine of Aging 2024-01-01

Background/Aims: High Monomeric Polyphenols Berries Extract (HMPBE) is a formula highly rich in polyphenols clinically proven to enhance learning and memory. It currently used enhances cognitive performance including accuracy, working memory concentration. Methods: Here, we investigated for the first time beneficial effects of HMPBE mouse model acute chronic traumatic brain injury (TBI). Results: HMPBE, at dose 15 mg/kg was able reduce histological alteration as well inflammation lipid...

10.33594/000000731 article EN cc-by-nc-nd Cellular Physiology and Biochemistry 2024-10-06
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