A5057053286- SARS-CoV-2 and COVID-19 Research
- Medicinal Plants and Bioactive Compounds
- COVID-19 Clinical Research Studies
- Inflammatory Biomarkers in Disease Prognosis
- SARS-CoV-2 detection and testing
- Immune cells in cancer
- Vestibular and auditory disorders
- Diet, Metabolism, and Disease
- Genetic and Environmental Crop Studies
- Regulation of Appetite and Obesity
- Cancer, Lipids, and Metabolism
- Rocket and propulsion systems research
- Combustion and Detonation Processes
- Seed and Plant Biochemistry
- Diet and metabolism studies
- Neurological Disease Mechanisms and Treatments
- Vaccine Coverage and Hesitancy
- Advanced Combustion Engine Technologies
- Saffron Plant Research Studies
- Cancer Immunotherapy and Biomarkers
- Graphene and Nanomaterials Applications
- Plant Genetic and Mutation Studies
- Hearing, Cochlea, Tinnitus, Genetics
- Genetics, Aging, and Longevity in Model Organisms
- Plant Stress Responses and Tolerance
University of Catania
2014-2024
UCLouvain
2024
Istituto Ortopedico Galeazzi
2021-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2021-2022
Fondazione IRCCS Istituto Nazionale dei Tumori
2020-2021
The antioxidant and anti-inflammatory effects of hormetic nutrition for enhancing stress resilience overall human health have received much attention. Recently, the gut-brain axis has attracted prominent interest preventing therapeutically impacting neuropathologies gastrointestinal diseases. Polyphenols polyphenol-combined nanoparticles in synergy with probiotics shown to improve gut bioavailability blood-brain barrier (BBB) permeability, thus inhibiting oxidative stress, metabolic...
Background: Meniere's disease (MD) is a cochlear neurodegenerative disease. Hearing loss appears to be triggered by oxidative stress in the ganglion neurons of inner ear. Objective: Here, we confirm variation markers and inflammation patients with Meniere hypothesize that chronic treatment Coriolus mushroom helps response acts on α-synuclein NF-kB-mediated inflammatory processes. Methods: Markers were evaluated MD or without for 3 6 months. Results: had small increase Nrf2, HO-1, γ-GC,...
Abstract Objectives After exceptional research efforts, several vaccines were developed against SARS-CoV-2 which sustains the pandemic COVID-19. The Comirnaty vaccine showed high efficacy in clinical trials and was first to be approved for its distribution general population. We evaluated immune response induced by dose different sex/age groups subjects with or without naturally present anti-SARS-CoV-2 antibodies. Methods As part of an Italian multicenter project ( Covidiagnostix ), serum...
Abstract Background Serological tests can be used to detect antibodies in the serum of subject's after SARS‐CoV‐2 infection and vaccination. Currently, variability antibody titers availability a multiplicity serological have made it necessary highlight their appropriateness limitations various diagnostic settings. Methods This study is part Covidiagnostix, multicenter project aimed at assessment health technology tests. Based on data gained from analysis over 5000 subjects, selected number...
9547 Background: HPD occurs in ≃10-25% of NSCLC pts upon single-agent ICI and correlates with poor prognosis. High circulating neutrophil count neutrophils/lymphocytes ratio have been associated shorter survival pts. In mouse lung cancer models, interleukin-17 (IL-17) promoted tumour growth increasing intratumoral neutrophils. The role specific and/or tumour-associated neutrophils driving is currently unknown. Methods: treated single agent were assessed for neutrophils’ phenotype....
Abstract Background: HPD has been described in 14-26% of NSCLC pts upon single agent ICI and correlates with poor survival. Currently, occurrence not explored ICI-PCT biomarkers are lacking. Although high circulating neutrophils (Ns) correlated pts, the role specific Ns subsets is unknown. Methods: treated 1st line as or combination PCT were assessed for Ns' phenotype. Tumor response was evaluated by RECIST 1.1. required 3 assessment (2 before ICI, 1 ICI) defined delta tumor growth rate...