Purpose: We investigated the presence of impaired endothelial function in individuals with post-acute sequelae coronavirus disease-2019 (PASC) compared to healthy and explored efficacy combined exercise training restoring or improving those PASC. Methods: Study I was a cross-sectional study which between PASC (n = 29, mean age 22.9 ± 3.9 year) 42, 21.7 2.0 year). II, an intervention design, if 14) could reverse decline associated controls 14). The program included aerobic, resistance,...

This study aimed to examine the associations of leisure time physical activity (LTPA) and occupational (OPA) with prevalence hypertension, while exploring sex disparities in these associations.

Ovarian aging is a major obstacle in assisted reproductive medicine because it leads to ovarian dysfunction women of advanced age. Currently, there are no effective treatments cure age-related dysfunction. In this study, we investigated the effect MIT-001 on function aged ovaries. Young and old mice were utilized study. was intraperitoneally administered, number follicles oocytes analyzed. Each group then retrieved for RNA protein isolation. Total subjected mRNA next-generation sequencing....

It remains unclear whether the hemodynamic effects of isometric handgrip exercise (IHG) are comparable to those aerobic (AE). This study investigated efficacy IHG in reducing central and ambulatory blood pressure older hypertensive participants compared its with AE.

Abstract Objective: This study examined the relationship between changes in physical activity and their impact on exercise capacity health-related quality of life over a 3-year span patients with CHD. Methods: We evaluated 99 young CHD, aged 13–18 years at outset. Physical activity, life, were assessed via questionnaires peak oxygen uptake measurements baseline after 3 years; measures estimated two time points categorised into quartiles. Participants stratified according to achieved (active)...

Stair climbing is a form of physical activity that can be easily accessible in worksites and public settings, but it remains unclear whether stair exercise more effective improving vascular health than walking exercise. The aim this study was to compare the short-term effects on function healthy young adults. Eighteen adults were randomized either group (n=10) or (n=8). performed inside building, while involved brisk treadmill at same intensity (50-60% heart rate reserve) for 2 weeks, 30...

Purpose: Isometric handgrip exercise (IHE) has a favorable cardiovascular effect and improves hemodynamic responses.Whether IHE attenuates stress-related reactivity assessed during sympathetic challenge remains unexplored.We tested the hypothesis that an acute bout of would improve carotid arterial function attenuate vasoreactivity response to stress in healthy adults.Methods: In randomized cross-over design, sixteen adults (aged 21.8±3.1 years) were enrolled.Participants completed two...

Purpose: Moderate-intensity continuous training (MICT) improves exercise capacity with vascular benefits, but time constraints hinder consistent adherence.High-intensity interval (HIIT) has emerged as a time-efficient alternative, repeated sprint (RST) being the shortest format.We hypothesized that RST would be effective MICT in improving function and young adults.Methods: Twenty-three adults (mean age, 26.2±3.8years) were randomly assigned to either or MICT.RST involved 20 sets of 4-second...

Oviducts have specific biomechanical properties that support fertilization and preimplantation embryo development, both of which are essential for successful pregnancy. However, conventional plastic-based human culture does not recapitulate the environment oviduct. Therefore, oviduct mimic systems accurately emulate biophysical conditions reproductive cells a significant unmet clinical need. In present study, we designed three-dimensional (3D)-bioprinted optimal soft hydrogel system mimics...

PURPOSE: We examined the hypothesis that cardiorespiratory fitness (CRF), defined as maximal oxygen uptake, predicts risk of incident cardiometabolic syndrome (CMS) having ≥3 relevant factors and is prospectively associated with continuous CMS score in healthy men. METHODS: Participants were 2,742 Korean men who underwent general health examinations had no evidence CMS, cardiovascular diseases, diabetes, hypertension at baseline. Baseline CRF was directly measured by peak uptake (VO2peak)...

Incontinentia pigmenti is characterized by irregular linear blisters with erythematous lesions which are developed from birth or later, verrucous papules on the extremities noted after a few weeks months, and appearance of streaks, spots swirls hyperpigmentation. This disorder known as systemic caused defect at developmental stage organs originated ectoderm mesoderm. We experienced an incontinentia in male newborn infant who did not have any family history had cutaneous lesions, were bullous...

Purpose: Recovery from exercise is a vulnerable phase that has been linked to increased susceptibility sudden cardiovascular events.Cigarette smoking increases the risk of mortality and morbidity.We tested hypothesis postexercise cigarette would attenuate hemodynamics vascular function during recovery in young men.Methods: Thirteen habitual smokers (age, 22±3 years; body mass index, 25.1±3.6 kg/m 2 ) participated (1) (0.6 mg nicotine) (2) sham (SHAM) immediately (30 minutes on treadmill; 40%...

Purpose: The purpose of this study was to compare the antihypertensive effects isometric handgrip exercise (IHG) versus aerobic (AE) on clinic, central and 24-hour ambulatory blood pressures in elderly hypertensive patients. Methods: We conducted a randomized controlled trial with three-arm design. Fifty-four patients (mean age 69 ± 6 years) were IHG training (n = 17), AE 19), or non-exercise control group 18; CON) for 12 weeks (3 times per week). Bilateral performed four 2 min at 30%...

Purpose: Regular aerobic exercise improves capacity and quality of life in children with congenital heart disease (CHD), but it remains unclear whether would improve vascular function CHD.We tested the hypothesis that acute bout virtual reality (VR) exergame CHD.Methods: In a single-arm study, eight (age, 9±1 years; five males) CHD participated VR (30 minutes at 40% rate reserve) using stationary cycle ergometer head mount display.Endothelial arterial stiffness as surrogate markers were...

Purpose: Numerous studies have reported the effects of interrupting prolonged sitting with aerobic exercise on vascular and postprandial function, but resistance for remain unclear.We tested hypothesis that intermittent activity breaks would attenuate sittinginduced metabolic dysfunction.Methods: Fourteen healthy adults (age, 24±2 years; body mass index, 22.0±2.4kg/m 2 ) completed two trials in a randomized cross-over design.During 4-hour after high-fat meal, participants underwent either...

While interrupting prolonged sitting with aerobic exercise has been demonstrated to attenuate endothelial dysfunction and postprandial metabolism, less is known about the effect of resistance exercise. PURPOSE: compare effects as a strategy for on vascular function after high-fat meal in healthy adults. METHODS: Using randomized crossover study design, fourteen young adults (8 males, 24 ± 2 yrs, BMI: 22.0 2.4 kg/m2) participated all three trials. Participants performed either (AE, 5 minutes...