A5081477104- Diabetes Management and Research
- Body Composition Measurement Techniques
- Prostate Cancer Diagnosis and Treatment
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Nutrition and Health in Aging
- Diabetes and associated disorders
- Heart Rate Variability and Autonomic Control
- Urinary Tract Infections Management
- Estrogen and related hormone effects
- Neurological Disorders and Treatments
- Pancreatic function and diabetes
- Blood Pressure and Hypertension Studies
- Machine Learning in Healthcare
- Urinary Bladder and Prostate Research
- Cardiovascular Disease and Adiposity
- Cardiovascular Syncope and Autonomic Disorders
- Mobile Health and mHealth Applications
- Adrenal and Paraganglionic Tumors
- Ovarian cancer diagnosis and treatment
- Ovarian function and disorders
- Hormonal Regulation and Hypertension
- Surgical site infection prevention
- Cardiovascular Function and Risk Factors
- Genital Health and Disease
- Dialysis and Renal Disease Management
CHA Gangnam Medical Center
2020-2024
CHA University
2020-2024
Maria Fertility Hospital
2023
Sungkyunkwan University
2019-2021
Samsung Medical Center
2019-2021
Kwangju Christian Hospital
2008-2017
Background: As the use of continuous glucose monitoring (CGM) has increased, time in range (TIR) and other core CGM metrics are now emerging as for clinical targets assessing diabetic complications, beyond HbA1c. This study investigated association between CGM-derived TIR, hyperglycemia, hypoglycemia metrics, albuminuria. Methods: A total 866 subjects with type 2 diabetes who underwent 3 or 6 days had urinary albumin-to-creatinine ratio (ACR) measurements were retrospectively reviewed....
The automation of insulin treatment is the most challenge aspect glucose management for type 1 diabetes owing to unexpected exogenous events (e.g., meal intake). In this article, we propose a novel reinforcement learning (RL) based artificial intelligence (AI) algorithm fully automated pancreas (AP) system.A bioinspired RL designing method was developed infusion. This has reward functions that imply temporal homeostatic objective and discount factors reflect an individual specific...
Heart failure with preserved ejection fraction is an emerging global health issue attributed to ageing population. However, the association between low skeletal muscle mass, sarcopenic obesity, and left ventricular diastolic dysfunction remains unclear. In current study, we aimed investigate relationship in a large cohort of Korean adults.We conducted cross-sectional study 31 258 subjects who underwent examinations at Samsung Medical Centre's Health Promotion Centre Seoul, Republic Korea....
Objectives To estimate the prevalence of fluoroquinolone‐resistant rectal flora in patients undergoing transrectal ultrasound‐guided prostate needle biopsy and to identify high‐risk groups. Methods From January 2015 March 2016, swabs 557 men who underwent were obtained from five institutions. Clinical variables, including demographics, swab culture results infectious complications, evaluated. Univariable multivariable analyses used risk factors for fluoroquinolone resistance complications....
Abstract We aimed to identify the association between low skeletal muscle, sarcopenic obesity, and incidence of albuminuria in general population using a longitudinal study. Data from 29,942 subjects who underwent two or more routine health examinations 2006 2013 were retrospectively reviewed. Relative muscle mass was presented index (SMI), measure body weight-adjusted appendicular estimated by bioelectrical impedance analysis. The cumulative 981 (3.3%) during 7-year follow-up period. hazard...
Abstract Background Despite the numerous healthcare smartphone applications for self-management of diabetes, patients often fail to use these consistently due various limitations, including difficulty in inputting dietary information by text search and inconvenient non-persistent self-glucose measurement home glucometer. We plan apply a digital integrated platform using an artificial intelligence (AI)-based management solution continuous glucose monitoring system (CGMS) overcome those...
Frequent failure of adrenal vein (AV) cannulation is a major obstacle to the universal use sampling (AVS) for subtyping primary aldosteronism (PA). This study aimed confirm and modify value previously reported AVS parameter PA in case on one side.Successfully catheterized studies 157 patients (121 as derivation cohort 36 validation cohort) from two tertiary hospitals were retrospectively reviewed. The AV/inferior vena cava (IVC) index was defined by dividing aldosterone/cortisol ratio (ACR)...
Cardiovascular autonomic neuropathy (CAN) is a major cause of morbidity and mortality in diabetes patients. Although several risk factors for CAN progression have been established, whether reversible remains unclear the clinical associated with recovery not identified. This study aimed to determine related recovery.Type 2 patients but free cardiovascular disease at baseline were enrolled followed 2-3 years this retrospective longitudinal study. was classified as early (one abnormal...
Ovarian aging hampers in vitro fertilization assisted reproductive medicine and has no cure. Lipoprotein metabolism is associated with ovarian aging. It remains unclear how to overcome poor follicular development Upregulation of the low-density lipoprotein receptor (LDLR) enhances oogenesis mouse ovaries. This study investigated whether upregulation LDLR expression using lovastatin activity mice. We performed superovulation a hormone used upregulate LDLR. histologically analyzed functional...
Purpose Recent studies have highlighted an increasing trend of infectious complications due to fluoroquinolone-resistant organisms among men undergoing transrectal prostate biopsy. This study evaluated the current incidence infective after trans-rectal biopsy for identification risk factors in Korean who received fluoroquinolone prophylaxis. Materials and Methods A prospective, multicenter was conducted Korea from January December 2015. Prostate biopsies performed with prophylaxis during 3...
See the reply "Letter: An Electronic Health Record-Integrated Computerized Intravenous Insulin Infusion Protocol: Clinical Outcomes and in Silico Adjustment (Diabetes Metab J 2020;44:56-66)" Volume 44 on page 354.
Background Cardiovascular autonomic neuropathy (CAN) is a common microvascular complication of diabetes and related to albuminuria in diabetic nephropathy (DN). Urinary N-acetyl-β-D-glucosaminidase (uNAG) renal tubular injury marker which has been reported as an early DN even patients with normoalbuminuria. This study evaluated whether uNAG associated the presence severity CAN type 1 mellitus (T1DM) without nephropathy. Methods cross-sectional comprised 247 subjects T1DM chronic kidney...
Studies of genetic variation in the prostate-specific antigen (PSA) gene have improved diagnostic accuracy PSA for diagnosing prostate diseases Caucasians. However, reference ranges and pharmacokinetics differ significantly according to race. Therefore, we evaluated association between variations promoter area benign prostatic hyperplasia (BPH) phenotypes Korean BPH patients.One hundred twenty-one men were enrolled. The initial serum level, size, changes at 3 months after treatment with...
Purpose: Circumcision is widely practiced in Korea, but its implementation still controversial, especially among younger parents. Using a questionnaire study, we tried to determine the rate of circumcision elementary school boys and parental concerns about phimosis circumcision. We then compared our findings with previously published literature. Materials Methods: Between May June 2007, randomly selected five schools distributed self-administered questionnaires parents 2,712 from these...
Objectives: The fact that metabolic syndrome is accompanied by a low-grade inflammation suggests may play an important role in the etiology. aim of our study was to assess association between heterogeneity status and incidence (MetS) metabolically healthy persons who are either obese or nonobese. Methods: This longitudinal included all underwent four more follow-up comprehensive health examinations annually biennially from August 2006 through 2013 at Health Promotion Center Samsung Medical...