A5060421369- Drug-Induced Adverse Reactions
- Contact Dermatitis and Allergies
- Urticaria and Related Conditions
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Peptidase Inhibition and Analysis
- Cancer Immunotherapy and Biomarkers
- Food Allergy and Anaphylaxis Research
- Protein Hydrolysis and Bioactive Peptides
- Aquaculture Nutrition and Growth
- Aquatic life and conservation
- Studies on Chitinases and Chitosanases
- Fish Biology and Ecology Studies
Siriraj Hospital
2024
Mahidol University
2024
Chulalongkorn University
2024
Kasetsart University
2014
Background: Immune evasion in cancer is a multifaceted process that synchronizes pro-tumoral immune infiltration, immunosuppressive inflammation, and inhibitory checkpoint expression (IC). Recent developments have immunotherapies such as blockade (ICB) chimeric antigen receptor T-cell (CAR-T) therapy effectively impede this but benefit limited patient cohort. This investigation introduces systemic immunotherapeutic strategy by inhibition of master-regulators (MR-IE). Methods: We utilized the...
ABSTRACT Drug reactions with eosinophilia and systemic symptoms (DRESS) Stevens‐Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) are severe cutaneous adverse hypersensitivity distinct clinical manifestations. Regulatory T (Treg) cells may behave differently in these syndromes, contributing to their diverse features outcomes. This study compared Treg dynamics between DRESS SJS/TEN patients during the acute recovery phases. Flow cytometry quantitatively analysed defined immunophenotype of...
Background: Cancer immune evasion is a multifaceted process that synchronizes pro-tumoral infiltration, immunosuppressive inflammation, and inhibitory checkpoint expression (IC). Current immunotherapies combat this issue by reinstating immunosurveillance of tumors; however, it benefits limited patient population. Thus, more effective immunotherapeutic strategy warranted to cater specific populations. This investigation introduces novel via inhibition master regulators (MR-IE). Methods:...