A5059031291- Particle physics theoretical and experimental studies
- Quantum Chromodynamics and Particle Interactions
- High-Energy Particle Collisions Research
- Neutrino Physics Research
- Protein Hydrolysis and Bioactive Peptides
- Computational Physics and Python Applications
- Congenital Heart Disease Studies
- Gut microbiota and health
- Particle Detector Development and Performance
- Particle Accelerators and Free-Electron Lasers
- Diet and metabolism studies
- Biochemical effects in animals
- GABA and Rice Research
- Advanced biosensing and bioanalysis techniques
- Coronary Artery Anomalies
- Nuclear physics research studies
- Aortic Disease and Treatment Approaches
- Advanced Glycation End Products research
- Tracheal and airway disorders
- Parasitic infections in humans and animals
- Dark Matter and Cosmic Phenomena
- Congenital Anomalies and Fetal Surgery
- Adipose Tissue and Metabolism
- Advanced Nanomaterials in Catalysis
- Food composition and properties
Henan Agricultural University
2022-2025
Henan University
2024-2025
Tianjin Chengjian University
2025
South China Normal University
2025
Sichuan University
2020-2024
West China Hospital of Sichuan University
2020-2024
Istituto Nazionale di Fisica Nucleare, Sezione di Pisa
2024
European Organization for Nuclear Research
2018-2024
Nanchang University
2024
Tianjin University
2023-2024
Precise genome-editing platforms are versatile tools for generating specific, site-directed DNA insertions, deletions, and substitutions. The continuous enhancement of these has led to a revolution in the life sciences, which promises deliver novel therapies genetic disease. can be traced back 1950s with discovery DNA's double-helix and, after 70 years development, evolved from crude vitro applications wide range sophisticated capabilities, including vivo applications. Nonetheless, precise...
Potentilla discolor Bunge (PDB), a perennial herb, has been used as traditional Chinese medicine in the therapy of many diseases. The aim current study was to investigate effect PDB water extract on systemic inflammation and gut microbiota type 2 diabetic (T2D) mice induced by high-fat diet (HFD) streptozotocin (STZ) injection. C57BL/6J were randomly divided into normal (ND) group, T2D group (diabetic treated with at dose 400 mg/kg body weight). Results showed that significantly decreased...
The effects of synbiotic yogurt supplemented with inulin on the pathological manifestations and gut microbiota-bile acid axis were investigated using a dehydroepiandrosterone (DHEA)-induced polycystic ovary syndrome (PCOS) mice model. Female C57BL/6J injected subcutaneously DHEA at dose 6 mg/100 g BW for 20 days to establish PCOS mouse Then, treated containing (6% w/w) 15 mL/kg 24 days. Results showed that supplementation enriched decreased body weight gain, improved estrus cycles...
In this study, the effects of γ-aminobutyric acid (GABA) on physio-biochemical metabolism, phenolic accumulation, and antioxidant system enhancement in germinated wheat under drought stress was investigated. The results showed that exogenous GABA reduced oxidative damage seedlings caused by enhanced content phenolics, with 1.0 mM being most effective concentration. Six acids were detected bound form, including p-hydroxybenzoic acid, vanillic syringic p-coumaric ferulic sinapic acid. However,...
Purpose This study aims to examine the effects of perceived warmth and competence humanoid robots on customer tolerance service failure through affective response boundary condition relationship norms. Design/methodology/approach Two experimental studies were conducted investigate robots’ physical appearances mediating role anger. The influence norms is also explored. Findings results reveal that perception (vs. competence) robot leads less (more) anger, which significantly in failure....
Recently, casein glycomacropeptide (GMP)-derived peptide was found to possess potent antioxidant and anti-inflammatory activities. In this study, the improvement effects underlying molecular mechanisms of GMP-derived on hepatic insulin resistance were investigated.The IPPKKNQDKTE identified from GMP papain hydrolysates by LC-ESI-MS/MS. Effects glucose metabolism expression levels signaling proteins in high glucose-induced insulin-resistant HepG2 cells evaluated. Results showed that...
Gut microbiota has been identified as an important factor in the link between nutrient excess and obesity. The aim of this study was to confirm whether bovine α-lactalbumin hydrolysates (LAH) can ameliorate high-fat diet (HFD)-induced endotoxemia systematic inflammation by modulating structure gut mice. results showed that LAH changed overall HFD-induced obese increased Bacteroidetes/Firmicutes ratios relative abundance S24-7, Lachnospiraceae Blautia. Spearman's correlation analysis revealed...
The anti-inflammatory effect of sea cucumber peptides (SCP) in lipopolysaccharide (LPS)-stimulated RAW264.7 murine macrophages was tested. SCP significantly reduced LPS-induced nitric oxide release by inhibiting the inducible synthase mRNA expression without affecting cell viability. inflammatory cytokines including tumour necrosis factor-α, interleukin (IL)-1β and IL-6 suppressed. inhibited degradation inhibitor κBα (IκBα) nuclear transposition NF-κB p65, resulting decreased...
Milk fat globule membrane (MFGM), a protein-lipid complex surrounding the globules in milk, has many health benefits. The aim of current study was to investigate whether MFGM could prevent obesity through inhibiting adipogenesis and promoting brown remodeling white adipose tissue (WAT) mice fed with high-fat diet. C57BL/6 were normal diet (ND), (HFD), HFD plus at 100 mg/kg BW, 200 BW or 400 for 8 weeks. Results showed that suppressed body weight gain induced by HFD, reduced mass accompanied...
Milk fat globule membrane (MFGM), which contains abundant glycoproteins and phospholipids, exerts beneficial effects on intestinal health immunomodulation. The aim of this study was to evaluate the protective possible underlying mechanisms MFGM cow's milk allergy (CMA) in a <i>β</i>-lactoglobulin (BLG)-induced allergic mice model. supplemented induced by BLG at dose 400 mg/kg body weight. Results demonstrated that alleviated food symptoms, decreased serum levels lipopolysaccharide,...
Poria cocos peel residue (PCPR) still contains much soluble dietary fiber (SDF), steam explosion (SE) treatment was applied to PCPR create a superior SDF. Steam pressure of 1.2 MPa, residence period 120 s, and moisture content 13% were the optimized parameters for SE PCPR. Under circumstances, enhanced its SDF yield from 5.24% 23.86%. Compared original SDF, SE-treated displayed improved enzyme inhibition, including inhibition α-amylase pancreatic lipase, also water holding, oil swelling,...
Milk fat globule membrane (MFGM), which contains abundant polar lipids and glycoproteins, can narrow the gap in growth development between breast-fed infant-formula-fed babies. The objective of this study is to evaluate effect MFGM supplementation infant formula on intestinal epithelium maturation, tight junctions, gut colonization rat pups.Sprague Dawley pups consume one five diets from postnatal day 8, including breastfeeding (BF), (IF), containing at 260 mg kg-1 body weight (BW), 520 BW,...
Pre-pregnancy obesity and high-fat diet (HFD) during pregnancy lactation are associated with neurodevelopmental delay in offspring. This study aimed to investigate whether milk fat globule membrane (MFGM) supplementation obese dams could promote neurodevelopment Obese female rats induced by HFD were supplemented MFGM lactation. Maternal exposure significantly delayed the maturation of neurological reflexes inhibited neurogenesis offspring, which recovered maternal supplementation. Gut...
Many researchers have found that Pb exposure can cause oxidative stress damage to the body’s tissue. Black soybean peptide (BSP) has a variety of physiological functions, especially in terms stress. Nevertheless, mitigation function BSPs on Pb-induced PC12 cells not been clearly defined. In this study, cell viability was detected by CCK8. Oxidative indicators, such as ROS, GSH/GSSG, MDA, SOD, CAT, GPx, and GR, were tested with biochemical kit. Protein expression Keap1, Nrf2, TXNIP measured...