- Foot and Ankle Surgery
- Bone fractures and treatments
- Hip and Femur Fractures
- Orthopedic Surgery and Rehabilitation
- Orthopedic Infections and Treatments
- Nail Diseases and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Hip disorders and treatments
- Bacteriophages and microbial interactions
- Musculoskeletal Disorders and Rehabilitation
- Pelvic and Acetabular Injuries
- Poisoning and overdose treatments
- Emergency and Acute Care Studies
- Infectious Diseases and Tuberculosis
- Mycobacterium research and diagnosis
- Bone and Joint Diseases
- Ultrasound in Clinical Applications
- Dupuytren's Contracture and Treatments
- Trauma and Emergency Care Studies
- Cardiac Arrest and Resuscitation
- Genomics and Phylogenetic Studies
- Surgical Sutures and Adhesives
- Cardiac, Anesthesia and Surgical Outcomes
- Opioid Use Disorder Treatment
- Trauma Management and Diagnosis
Massachusetts General Hospital
2024
University of Kentucky
2022-2024
Brigham and Women's Hospital
2024
Harvard University
2024
Foundation for Human Potential
2024
Centre College
2020
OBJECTIVES: To determine whether scheduled low-dose, short-term ketorolac modulates cytokine concentrations in orthopaedic polytrauma patients. METHODS: Design: Secondary analysis of a double-blinded, randomized controlled trial. Setting: Single Level I trauma center from August 2018 to October 2022. Patient Selection Criteria: Orthopaedic patients between 18-75 years with New Injury Severity Score greater than 9 were enrolled. Participants receive 15 mg intravenous (IV) every 6 hours for up...
Background: Osteonecrosis is a complication of talar neck fractures associated with chronic pain and poor functional outcomes. The Hawkins sign, the radiographic presence subchondral lucency seen in dome 6 to 8 weeks after trauma, strong predictor preserved vascularity. This study sought assess accuracy sign contemporary cohort factors inaccuracy. Methods: A retrospective review at level-I trauma center from 2008 2016 was conducted. Both osteonecrosis were evaluated on radiographs....
OBJECTIVES: To compare radiographic and clinical outcomes in non-operative management of humeral shaft fractures treated initially with coaptation splinting (CS) followed by delayed functional bracing (FB) versus treatment immediate FB. METHODS: Design : Retrospective cohort study Setting: Academic Level 1 Trauma Center Patient Selection Criteria: Patients closed managed non-operatively initial CS FB or from 2016 to 2022. younger than 18 years and/or less 3 months follow-up were excluded....
To determine whether primary arthrodesis (PA) or open reduction and internal fixation (ORIF) results in better functional outcomes through patient-reported outcome measures (PROMs). Reoperation rates surgical characteristics among the 2 groups are evaluated as well.
Abstract Background Whole genome sequencing promises to revolutionize our ability link genotypic and phenotypic variation in a wide range of model non-model species. Results Here we describe the isolation characterization novel mycobacteriophage named BGlluviae that grows on Mycobacterium smegmatis mc 2 155. normally produces turbid plaques but spontaneous clear plaque was also recovered. The genomic DNA from pure populations phage mutant were sequenced. A single substitution, at amino acid...
OBJECTIVES: To determine if talar neck fractures with concomitant ipsilateral foot and/or ankle (TNIFAFs) are associated higher rates of avascular necrosis (AVN) compared to isolated (ITNs). METHODS: Design: Retrospective Cohort Setting: Single Level I Trauma Center Patient Selection Criteria: Skeletally mature patients who sustained from January 2008 2017 at least six months follow-up. Based on radiographs the time injury, were classified as ITN or TNIFAF and by Hawkins classification....
Introduction/Purpose: Avascular necrosis (AVN) is a complication of talar neck fractures associated with chronic pain and poor functional outcomes. Hawkins sign, the radiographic presence subchondral lucency seen in dome 6 to 8 weeks after trauma, considered be strong predictor preserved talus vascularity. The study sought assess accuracy sign large, contemporary cohort factors inaccuracy. Methods: A retrospective review all from single level I trauma center 2008 2016 was performed. AVN were...
The objective of this study was to compare the quality syndesmotic reduction with ankle in maximal dorsiflexion versus neutral plantarflexion (normal resting position).
To examine the effect of local aqueous tobramycin injection adjunct to perioperative intravenous (IV) antibiotic prophylaxis in reducing fracture-related infections (FRIs) following reduction and internal fixation open fractures.
To compare outcomes of nonoperative and percutaneous fixation geriatric fragility lateral compression 1 (LC1) pelvic ring fractures.
Category: Trauma; Ankle Introduction/Purpose: To compare the quality of syndesmotic reduction with ankle in maximal dorsiflexion versus neutral plantarflexion (normal resting position). Methods: Two fellowship-trained orthopaedic surgeons disrupted syndesmoses 10 cadaveric specimens from 5 donors. All ankles were initially placed and subsequently reduced stabilized one 0.062-inch K-wire a quadricortical fashion. Post-reduction computed tomography (CT) scans then obtained. This process was...
Category: Ankle Arthritis; Trauma Introduction/Purpose: Intraarticular pilon fractures have a high rate of posttraumatic osteoarthritis (PTOA) despite anatomic reduction the articular surface. Elevated synovial inflammatory proteins triggered by injury contribute to PTOA development.MicroRNAs (miRNA), regulators gene expression, are dysregulated in cartilage osteoarthritic joints, and their modulation may deter destruction. Specifically, miRNA-146a is associated with normal development...
To determine whether scheduled low-dose, short-term ketorolac is associated with reduced length of stay, opioid use, and pain in orthopaedic polytrauma patients.Double-blinded, randomized controlled trial.One Level 1 trauma center.From August 2018 to October 2022, 70 patients between 18-75 years-old a New Injury Severity Score (NISS) > 9 were randomized. participants enrolled, 35 the group placebo group.15 mg intravenous (IV) every 6 hours for up 5 inpatient days or 2 mL IV saline similar...