A5045111376- Neural and Behavioral Psychology Studies
- Functional Brain Connectivity Studies
- Peptidase Inhibition and Analysis
- Neural dynamics and brain function
- Neuropeptides and Animal Physiology
- Aquaculture disease management and microbiota
- Multisensory perception and integration
- Heart Rate Variability and Autonomic Control
- Neuroscience and Music Perception
- Diabetes Treatment and Management
- Enhanced Recovery After Surgery
- Mental Health Research Topics
- Neurobiology of Language and Bilingualism
- Healthcare Systems and Public Health
- GDF15 and Related Biomarkers
- Inflammasome and immune disorders
- EEG and Brain-Computer Interfaces
- Aquaculture Nutrition and Growth
- Language, Metaphor, and Cognition
- Hearing Loss and Rehabilitation
- Alzheimer's disease research and treatments
- Human-Automation Interaction and Safety
- Hearing Impairment and Communication
- Nerve injury and regeneration
- Innovative Educational Techniques
Huaibei Normal University
2023-2024
Tongji University
2024
Shanghai East Hospital
2020-2024
Anhui University
2024
Shanghai Tenth People's Hospital
2024
Jiangsu Normal University
2013-2023
University of Science and Technology of China
2021
Guilin Medical University
2016-2020
Southwest Medical University
2020
West China Hospital of Sichuan University
2020
OBJECTIVE Hyperglycemia, inflammation, and oxidative stress are thought to be involved in the pathogenesis of cognitive decline. Dipeptidyl peptidase-4 (DPP4) is a newly identified adipokine related these risk factors. Hence, we aimed investigate association between plasma DPP4 activities mild impairment (MCI) elderly patients with type 2 diabetes. RESEARCH DESIGN AND METHODS We evaluated activity, inflammatory markers, parameters cross-sectional sample 1,160 diabetes aged 60 years or older...
Objective: Inflammation, oxidative stress and decreased glucagon-like peptide-1 (GLP-1) are risk factors for cognitive impairment. Dipeptidyl peptidase-4 (DPP4) was identified as a novel adipokine capable of enhancing these factors. Hence, we investigated the relationship between plasma DPP4 activity impaired function in elderly Chinese population with normal glucose tolerance. Methods: We performed cross-sectional study using data from 1229 participants (60 years or older) Guilin. Plasma...
EEG microstate analysis involves the examination of topographies scalp potential fields to indicate temporal dynamics resting-state networks on a millisecond time scale, through which we can investigate subsecond brain stress in individuals. The present study implemented method explore dynamic changes large-scale induced by acute stress. participants (n = 51) were randomly exposed condition 25) (induced Trier Social Stress Test, TSST) or control 26). Two 4-min blocks resting data recorded...
The histochemical distribution of acid phosphatase (ACP), alkaline (ALP), non‐specific esterase (NSE), peroxidase (POD) and mucous‐cell types was evaluated in the gastrointestinal tract half‐smooth tongue sole Cynoglossus semilaevis . enzymes were detected entire stretch tract. ACP activity found supranuclear region enterocytes lamina propria intestine, as well cytoplasm epithelial cells stomach. staining intensity anterior posterior intestines stronger than ALP striated border muscularis...
Reward plays a crucial role in enhancing response inhibition. While it is generally assumed that the process of inhibition involves attentional capture and stopping action, unclear whether this reflects direct impact reward on or rather an indirect mediation via capture. Here, we employed revised stop-signal task (SST) separated these two cognitive elements, by including continue signal required same motor as go trials, but also attention to cue, stop trials. We first confirmed engagement...
Background: Hyperglycemia, insulin resistance and hypertriglyceridesmia are risk factors for albuminuria in type 2 diabetes. Angiopoietin-like Protein 8(ANGPTL8) is a newly identified liver-derived hormone related to these factors. Hence, we aimed explore the relationship between ANGPTL8 Methods: Serum levels were determined groups of control (n = 50) diabetic patients with normoalbuminuria (A1, n 100), microalbuminuria (A2, 45), macroalbuminuria (A3, 33). Results: triglycerides...
ABSTRACT Objective The objective of this study was to assess the association plasma dipeptidyl peptidase-4 (DPP4) activity, brain-derived neurotrophic factor (BDNF), and DPP4/BDNF ratio (DBR) with moderate severe depressive symptoms in patients type 2 diabetes mellitus. Increased DPP4 activity decreased BDNF peripheral circulation have been implicated pathophysiology depression. Methods We performed a cross-sectional using data from 1535 main outcome measures were levels, DBR, inflammation...
Background: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are clinically severe disorders without available pharmacological therapies. Dynasore is a cell-permeable molecule that inhibits GTPase activity exerts protective effects in several disease models. However, whether dynasore can alleviate lipopolysaccharide (LPS)-induced ALI unknown. This study investigated the effect of on macrophage activation explored its potential mechanisms LPS-induced vitro vivo. Methods:...
Abstract Feedback information is essential for us to adapt appropriately the environment. The feedback-related negativity (FRN), a frontocentral negative deflection after delivery of feedback, has been found be larger outcomes that are worse than expected and it reflects reward prediction error derived from midbrain dopaminergic projections anterior cingulate cortex (ACC), as stated in reinforcement learning theory. In contrast, response-outcome (PRO) model claims neural activity...
Abstract Error processing is critical for adaptive behaviors. Acute stress has been found to influence error processing. However, the neural dynamic correlates underlying this modulation remain elusive. To address issue, we recruited 39 healthy male participants, who performed a two‐session task before and after an acute test while their behavioral EEG data were recorded. The participants randomly exposed either condition (Maastricht Stress Test) or control condition. consisted of several...
The immune system is one of the most complex regulatory systems in body and essential for maintenance homeostasis. Despite recent breakthroughs immunology, regulation etiology autoimmune diseases such as lupus remain unclear. Systemic erythematosus a systemic disease with abnormally inconsistently expressed pro-inflammatory cytokines. Pyroptosis form programmed cell death that associated erythematosus. thymus spleen are important organs involved Therefore, this study investigated difference...
Objective: Since decreased brain-derived neurotrophic factor (BDNF) and increased dipeptidyl peptidase-4 (DPP4) activity have both been implicated in the pathogenesis of mild cognitive impairment (MCI), aim our study was to evaluate association MCI with plasma DPP4 BDNF ratio (DBR) an elderly population normal glucose tolerance. Methods: We cross-sectionally measured C-reactive protein, interleukin-6, nitrotyrosine, 8-iso-PGF2a, calculated DBR a total 1,066 participants China. determined by...
It is generally assumed that task switching involves working memory, yet some behavioral studies question the relationship between memory and ability. This debate can be resolved by directly comparing brain activity pattern in processes. If neural patterns evoked such two tasks would exhibit higher similarity. Here, we employed to investigate characteristic of representation cognitive A conjunction analysis showed bilateral superior parietal lobule (SPL), insula, middle frontal gyrus (MFG),...
Cognitive flexibility is a core cognitive control function supported by the brain networks of whole-brain. Schizophrenic patients show deficits in conditions such as task-switching. A large number neuroimaging studies have revealed abnormalities local activations associated with schizophrenia, but relationship between impaired and whole-brain functional connectivity (FC) pattern unclear.