A5013693577- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Cancer-related gene regulation
- Epigenetics and DNA Methylation
- Heme Oxygenase-1 and Carbon Monoxide
- Eosinophilic Esophagitis
- Wnt/β-catenin signaling in development and cancer
- Microtubule and mitosis dynamics
- Reproductive System and Pregnancy
- Advanced Glycation End Products research
- RNA regulation and disease
- Phytochemistry and biological activity of medicinal plants
- Drug-Induced Hepatotoxicity and Protection
- Bioactive Compounds and Antitumor Agents
- Medical Research and Treatments
- Gastroesophageal reflux and treatments
- Mesenchymal stem cell research
- Endometriosis Research and Treatment
- Neonatal Respiratory Health Research
- melanin and skin pigmentation
- Natural product bioactivities and synthesis
- Cell death mechanisms and regulation
- 2D Materials and Applications
Jiangsu University
2020-2025
Huazhong Agricultural University
2025
Affiliated Hospital of Jiangsu University
2025
Shanghai East Hospital
2017-2024
Northeast Agricultural University
2016-2024
Affiliated Hospital of Guizhou Medical University
2024
Guizhou University
2022-2024
Hubei University of Technology
2023-2024
Jiaxing University
2024
Guangzhou University of Chinese Medicine
2024
The global prevalence of obesity is rising year by year, which has become a public health problem worldwide. In recent years, animal studies and clinical have shown that some lactic acid bacteria possess an anti-obesity effect. our previous study, mixed lactobacilli (
Abstract Inorganic mercury, though a key component of pediatric vaccines, is an environmental toxicant threatening human health via accumulating oxidative stress in part. Luteolin has been great interest because its antiinflammatory, anticarcinogenic and antioxidative effects. Here we hypothesized that luteolin would attenuate hepatotoxicity induced by acute inorganic mercury exposure. Kunming mice were treated with (100 mg/kg) 24 h after administration 4 mg/kg mercuric chloride (HgCl 2 )....
Inflammation and apoptosis play important roles in the initiation progression of acute lung injury (ALI). Our previous study has shown that progranulin (PGRN) exerts protective effects during LPS-induced ALI. Here, we have investigated potential PGRN-targeting microRNAs (miRNAs) regulating inflammation ALI highlighted role PGRN. PGRN were first confirmed. The function miR-34b-5p was determined by transfection a mimic or inhibitor intro vivo. level gradually increased subsequently...
To evaluate the clinical manifestations, endoscopic, and radiological characteristics, histological features, treatment of eosinophilic gastroenteritis in adult patients.The records 34 patients diagnosed as eight who had abdominal symptoms unexplained peripheral eosinophilia but no evidence tissue infiltration were reviewed analyzed.Thirteen a history asthma or allergic rhinitis, while 10 an history. Peripheral occurred 83.3% patients, IgE was elevated half, α2-macroglobulin 92.8% patients....
Lead (Pb) is a global environmental health hazard that leads to nephrotoxicity. However, the effective treatment of Pb-induced nephrotoxicity remains elusive. Grape seed procyanidin extract (GSPE) has beneficial properties for multiple biological functions. Therefore, present study investigated whether GSPE reduced as well protective mechanism in well-established 35-day Pb induced rat model. The results showed normalized oxidative stress, histological damage, inflammatory, apoptosis, and...
We, the Editors, Authors and Publisher of journal Artificial Cells, Nanomedicine, Biotechnology, have retracted following article:Tao Peng, Xiaoyan Liu, Jingtao Wang, Yu Zhenqiang Fu, Xingrong Ma, Junmin Li, Guifang Sun, Yangfei Ji, Jingjing Lu, Wencui Wan & Hong Lu (2019) Long noncoding RNA HAGLROS regulates apoptosis autophagy in Parkinson’s disease via regulating miR-100/ATG10 axis PI3K/Akt/mTOR pathway activation. 47:1, 2764–2774, DOI: 10.1080/21691401.2019.1636805Since publication,...
Liver disease has become an important risk factor for global health. Resveratrol (Res) is a natural polyphenol which widely found in foods and variety of biological activities. This study investigated the role microbiota-gut-liver axis Res relieving liver fibrosis induced by inorganic mercury exposure. Twenty-eight mice were divided into four groups (n = 7) treated with mercuric chloride and/or 24 weeks, respectively. The results showed that mitigated ileum injury restrained LPS alcohol...
Recently, interest in investigating the effects of long noncoding RNAs (lncRNAs) on endometrial receptivity (ER) has increased within field assisted reproductive technology. Therefore, objective this study is to identify and analyze role lncRNA LUCAT1 elucidate its specific mechanism regulating ER. Hub genes associated with ER are identified via Weighted gene co-expression network analysis (WGCNA) two datasets downloaded from GEO database. These hub WGCNA were subsequently validated. The...
MicroRNAs are members of the family noncoding small RNAs that regulate gene expression either by inhibiting mRNA translation or promoting degradation at posttranscriptional level. They play an important role in differentiation bone marrow-derived mesenchymal stem cells (MSCs) into neurons. However, microRNAs this process remains to be poorly understood. Studies have shown Notch signaling is involved regulating MSC differentiation. Here, we found microRNA-9 could promote neuronal Using...
Epithelial ovarian cancer (EOC) is the leading cause of death among all gynecological malignancies. Most patients are diagnosed in advanced stage and have distant metastasis ultimately. Salinomycin has been demonstrated to reduce invasive capacity multiple tumor cells. The objective this study was investigate effects salinomycin on EOC cell counting kit 8 (CCK-8) Boyden chamber assays showed that could effectively abilities proliferation, migration invasion western blot assay increase...
Although periostin was confirmed to facilitate the pathogenesis of endometriosis by enhancing migration, invasion, and adhesion human endometrial stromal cells (ESCs), its effect on epithelial (EECs) is still unknown. The current study aimed determine whether enhanced epithelial-mesenchymal transition (EMT) EECs. EECs were isolated from 12 women with endometriosis. migration invasion abilities evaluated transwell assays. Expressions proteins detected western blot. After treatment periostin,...
Although our previous studies have confirmed that 1, 3, 8-trihydroxy-6-methylant hraquinone (emodin) inhibits migration and invasion in epithelial ovarian cancer (EOC) cells, the underlying molecular mechanism remains unknown. Here, aim was to investigate effects of emodin on EOC cells study further this process, both vitro vivo.Cell proliferation evaluated by methylthiazolyl tetrazolium assay. Cell abilities were tested using transwell The expression integrin-linked kinase (ILK)...
With the development of science and technology, people increasingly rely on intelligent interactive products, thus promoting vigorous user interface industry. Software with high usability experience can improve users’ effectiveness satisfaction, as well viscosity. Taking three design software: Sketch, Adobe XD, Figma, which is most frequently used by industry practitioners students, research cases, this study compared discussed impact interaction layout combining subjective experiment...
Multi-walled carbon nanotube (MWCNT)-induced lung fibrosis leads to health concerns in human. However, the mechanisms underlying pathogenesis remains unclear. The adenosine (ADO) is produced response injury and serves a detrimental role fibrosis. In this study, we aimed explore ADO signaling progression of induced by MWCNT. MWCNT exposure markedly increased A2B receptor (A2BAR) expression lungs level bronchoalveolar lavage fluid, combined with elevation blood neutrophils, collagen fiber...