A5080473175- Advanced biosensing and bioanalysis techniques
- Wheat and Barley Genetics and Pathology
- Parasitic Infections and Diagnostics
- Quantum Dots Synthesis And Properties
- Genetic Mapping and Diversity in Plants and Animals
- Urban Green Space and Health
- Land Use and Ecosystem Services
- Biosensors and Analytical Detection
- Genetic diversity and population structure
- High-Energy Particle Collisions Research
- Particle physics theoretical and experimental studies
- Genetics and Plant Breeding
- Genomics and Phylogenetic Studies
- Quantum Chromodynamics and Particle Interactions
- Plant Virus Research Studies
- HIV Research and Treatment
- Rice Cultivation and Yield Improvement
- Aquaculture disease management and microbiota
- Molecular Sensors and Ion Detection
- Electrochemical sensors and biosensors
- Coccidia and coccidiosis research
- Immune Cell Function and Interaction
- Luminescence and Fluorescent Materials
- Identification and Quantification in Food
- Amoebic Infections and Treatments
Sanya University
2023-2025
Hainan University
2022-2025
Nanjing Agricultural University
2021-2025
Heze University
2015-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2013-2025
Baoji City Central Hospital
2025
Qingdao University
2025
Chengdu Institute of Biology
2015-2024
Chinese Academy of Sciences
2004-2024
Shenzhen Bay Laboratory
2022-2024
Marine stickleback fish have colonized and adapted to thousands of streams lakes formed since the last ice age, providing an exceptional opportunity characterize genomic mechanisms underlying repeated ecological adaptation in nature. Here we develop a high-quality reference genome assembly for threespine sticklebacks. By sequencing genomes twenty additional individuals from global set marine freshwater populations, identify genome-wide loci that are consistently associated with...
The intricate relationship between resistant starch (RS) and the gut microbiome presents a dynamic frontier in nutrition science. This review synthesizes current understandings of how RS, an indigestible form found naturally certain foods also enhanced through various modification methods, interacts with microbiome. We particularly focus on RS fermentation colon contributes to production beneficial volatile fatty acids (VFAs) such as butyrate, acetate, propionate. These VFAs have been...
In untreated human immunodeficiency virus type 1 (HIV-1) infection, most viral genomes in resting CD4(+) T cells are not integrated into host chromosomes. This unintegrated provides an inducible latent reservoir because cellular activation permits integration, gene expression, and production. It remains controversial whether HIV-1 is stable this preintegration state. Here, we monitored the fate of by using a green fluorescent protein (GFP) reporter carrying X4 envelope. After entry cells,...
Human immunodeficiency virus type 1 (HIV-1)-infected individuals who develop drug-resistant during antiretroviral therapy may derive benefit from continued treatment for two reasons. First, viruses can retain partial susceptibility to the drug combination. Second, selects that have reduced replication capacities relative archived, drug-sensitive viruses. We developed a novel single-cell-level phenotypic assay allows these effects be distinguished and compared quantitatively. Patient-derived...
A novel ultrasensitive immunoassay method was developed based on the electrochemical measurement of polyaniline, which catalytically produced by horseradish peroxidase-functionalized gold nanoparticle (HRP-Au NP) probe at an immunosensor. The immunosensor prepared step-wise first modifying electrode with reduced graphene oxide (rGO)/Au NPs nanocomposite followed immobilization capture antibodies its surface. After performing a sandwich immunoreaction, quantitatively captured HRP-Au NP...
Mutations of small effect underlie most adaptation to new environments, but beneficial variants with large fitness effects are expected contribute under certain conditions. Genes and genomic regions having on phenotypic differences between populations known from numerous taxa, sizes have rarely been estimated. We mapped over a generation in an F2 intercross marine lake stickleback population introduced freshwater pond. A quantitative trait locus map the number surviving offspring per female...
The multifunctional movement protein (MP) of Tomato mosaic tobamovirus (ToMV) is involved in viral cell-to-cell movement, symptom development, and resistance gene recognition. However, it remains to be elucidated how ToMV MP plays such diverse roles plants. Here, we show that interacts with the Rubisco small subunit (RbCS) Nicotiana benthamiana vitro vivo. In susceptible N. plants, silencing NbRbCS enabled induce necrosis inoculated leaves, thus enhancing virus local infectivity. development...
Here the distance dependence of metal-enhanced quantum dots (QDs) fluorescence in solution is studied systematically by capillary electrophoresis (CE). Complementary DNA oligonucleotides-modified CdSe/ZnS QDs and gold nanoparticles (Au NPs) were connected together hybridization complementary oligonucleotides, a model system (QD–Au) for study was constructed, which between Au NPs controlled adjusting base number oligonucleotide. In our CE experiments, only observed when ranged from 6.8 to...
Lead (Pb) is a global environmental health hazard that leads to nephrotoxicity. However, the effective treatment of Pb-induced nephrotoxicity remains elusive. Grape seed procyanidin extract (GSPE) has beneficial properties for multiple biological functions. Therefore, present study investigated whether GSPE reduced as well protective mechanism in well-established 35-day Pb induced rat model. The results showed normalized oxidative stress, histological damage, inflammatory, apoptosis, and...
The pathogen cereal cyst nematode (CCN) is deleterious to Triticeae crops and a threat the global crop yield. Accession no. 1 of Aegilops variabilis, relative Triticum aestivum (bread wheat), highly resistant CCN. Our previous study demonstrated that expression phenylalanine ammonia lyase (PAL) gene AevPAL1 in Ae. variabilis strongly induced by PAL, first enzyme phenylpropanoid metabolism, involved abiotic biotic stress responses. However, its role plant-CCN interaction remains unknown. In...
Current management of inflammatory bowel disease leaves a clear unmet need to treat the severe epithelial damage. Modulation Wnt signaling might present an opportunity achieve histological remission and mucosal healing when treating IBD. Exogenous R-spondin, which amplifies signals by maintaining cell surface expression Frizzled (Fzd) low-density lipoprotein receptor-related protein receptors, not only helps repair intestine damage, but also induces hyperplasia normal epithelium. may be...
Ecosystem services (ES) are key benefits that humans derive from natural ecosystems, including provisioning, regulating, and cultural services. As urbanization accelerates globally, urban green spaces (UGS), increasingly recognized for their role in improving environmental quality enhancing human well-being, provide essential ES help mitigate the effects of urbanization. However, factors influencing public preferences these services, particularly knowledge religiosity, remain underexplored....
DYF-1 is a highly conserved protein essential for ciliogenesis in several model organisms. In Caenorhabditis elegans, serves as an activator anterograde motor OSM-3 of intraflagellar transport (IFT), the ciliogenesis-required motility that mediates flagellar precursors and removal turnover products. zebrafish Tetrahymena influences cilia tubulin posttranslational modification may have more ubiquitous function than OSM-3. Here we address how biochemically interacts with IFT machinery by using...