A5078046206- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Sex work and related issues
- Adolescent Sexual and Reproductive Health
- HIV Research and Treatment
- Global Maternal and Child Health
- HIV/AIDS Impact and Responses
- Pneumocystis jirovecii pneumonia detection and treatment
- Vaccine Coverage and Hesitancy
- HIV/AIDS oral health manifestations
- Female Genital Mutilation/Cutting Issues
- Poverty, Education, and Child Welfare
- Genital Health and Disease
- Tuberculosis Research and Epidemiology
- Global Health and Surgery
- Hepatitis B Virus Studies
- Pharmaceutical studies and practices
- Cervical Cancer and HPV Research
- Zoonotic diseases and public health
- Climate Change and Health Impacts
- Family Support in Illness
- Health Systems, Economic Evaluations, Quality of Life
- Urologic and reproductive health conditions
- Childhood Cancer Survivors' Quality of Life
- Health disparities and outcomes
Fred Hutch Cancer Center
2022-2025
Seattle University
2018-2025
Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa
2022-2025
Kenya Medical Research Institute
2023
Fairview School District
2023
Gilead Sciences (United States)
2023
University of Washington
2018-2022
National Clinical Research
2018-2020
International Centre for Reproductive Health
2020
Ministry of Health
2020
Background HIV self-testing (HIVST) may play a role in addressing gaps testing coverage and as an entry point for prevention services. We conducted cluster randomized trial of 2 HIVST distribution mechanisms compared to the standard care among female sex workers (FSWs) Zambia. Methods findings Trained peer educators Kapiri Mposhi, Chirundu, Livingstone, Zambia, each recruited 6 FSW participants. Peer educator–FSW groups were 1 3 arms: (1) delivery (direct oral from educator), (2) coupon (a...
Background HIV self-testing allows testing at any place and time without health workers. may thus be particularly useful for female sex workers (FSWs), who should test frequently but face stigma financial barriers when accessing healthcare facilities. Methods findings We conducted a cluster-randomized controlled systems trial among FSWs in Kampala, Uganda, to measure the effect of 2 delivery models on linkage care outcomes. FSW peer educator groups (1 8 participants) were randomized either...
Introduction HIV self-testing (HIVST) is highly sensitive and specific, addresses known barriers to testing (such as stigma), recommended by the World Health Organization a option for delivery of pre-exposure prophylaxis (PrEP). Nevertheless, HIVST remains underutilized diagnostic tool in community-based, differentiated service models, possibly due concerns about result misinterpretation, which could lead inadvertent onward transmission HIV, delays antiretroviral therapy (ART) initiation,...
Zambia has a generalized HIV epidemic, and is concentrated along transit routes. Female sex workers (FSWs) are disproportionately affected by the epidemic. testing crucial first step for engagement in care prevention activities. However, to date little work been done with FSWs Zambia, known about barriers facilitators this population. FSW peer educators were recruited through existing worker organizations participation trial related among FSWs. We conducted five focus groups (N = 40) three...
HIV pre-exposure prophylaxis (PrEP) is highly effective for prevention of acquisition, but requires testing at regular intervals. Female sex workers (FSWs) are a priority population interventions in many settings, face barriers to accessing healthcare. Here, we assessed the acceptability self-testing during PrEP implementation among FSWs participating randomized controlled trial delivery models. We used data from two trials with identical protocols Zambia and Uganda. From September–October...
Abstract Introduction In Kenya, pre-exposure prophylaxis (PrEP) for HIV prevention is almost exclusively delivered at clinics. Developing novel PrEP delivery models important increasing the reach of PrEP. Delivery through pharmacies one approach utilized in US to improve accessibility. Retail are commonly used as a first-line access point medical care but have not been delivery. We conducted collaborative consultative meeting stakeholders develop pathway pharmacy-based Kenya. Methods January...
As countries scale up pre-exposure prophylaxis (PrEP) for HIV prevention, diverse PrEP delivery models are needed to expand access populations at risk that unwilling or unable clinic-based care. To identify factors may influence implementation of retail pharmacy-based in Kenya, we conducted in-depth interviews with 40 pharmacy clients, 16 providers, and 10 providers from two provinces. Most participants expressed strong support expanding pharmacies, though conditioned their acceptance on...
The delivery of daily, oral HIV pre-exposure prophylaxis (PrEP) at private pharmacies may overcome barriers to PrEP public healthcare facilities, including HIV-associated stigma, long wait times and overcrowding.At five private, community-based in Kenya, a care pathway for (ClinicalTrials.gov: NCT04558554) was piloted-the first its kind Africa. Pharmacy providers screened clients interested risk, then used prescribing checklist identify without medical conditions that might contraindicate...
Introduction: Maximizing the impact of new and forthcoming long-acting injectable HIV pre-exposure prophylaxis (PrEP) products will require novel delivery approaches that widen accessibility prioritize clients needs preferences. To understand potential barriers facilitators to delivering PrEP via private pharmacies in Kenya, we conducted qualitative formative research. Methods: From July September 2023, interviewed pharmacy providers, clients, other key stakeholders service Central Western...
Background: Online pharmacy HIV pre- and post-exposure prophylaxis (PrEP/PEP) provision is a novel strategy to expand prevention coverage. In the ePrEP pilot study, we found online PrEP/PEP was feasible reached populations at risk in Kenya. However, program costs data are lacking. Methods: We conducted costing within study Nairobi from 11/01/2022-12/29/2023. obtained expense reports time-and-motion observations staff interviews. estimated total unit first year of implementation, cost per...
Background: In Kenya, as in many African countries, private pharmacies are ubiquitous, frequently accessed, and underutilized for the delivery of HIV prevention services. Whether enabling to initiate manage clients on pre- post-exposure prophylaxis (PrEP PEP) leads greater uptake continuation than current standard-pharmacy referral clinic-based PrEP/PEP-is unknown. To address this gap inform how might partner with public sector, we testing several models pharmacy-delivered PrEP/PEP...
Background: Online pharmacy HIV pre- and post-exposure prophylaxis (PrEP/PEP) provision is a novel strategy to expand prevention coverage. In the ePrEP pilot study, we found online PrEP/PEP was feasible reached populations at risk in Kenya. However, program costs data are lacking. Methods: We conducted costing within study Nairobi from 11/01/2022-12/29/2023. obtained expense reports time-and-motion observations staff interviews. estimated total unit first year of implementation, cost per...
Female bar workers (FBW) in East Africa often conduct sex work to supplement their incomes, and may be vulnerable HIV acquisition. Pre-exposure prophylaxis (PrEP) offers protection against However, there is little research on FBW's sexual health. Our objective was determine risk behaviours interest PrEP among FBW the largest city Africa. Cross-sectional survey covering respondents' personal lives, including social behavioural factors for HIV. The aimed feasibility of working with prevalence...