A5025131671- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Sarcoma Diagnosis and Treatment
- Uterine Myomas and Treatments
- Cervical Cancer and HPV Research
- Estrogen and related hormone effects
- Endometriosis Research and Treatment
- Prostate Cancer Treatment and Research
- Prenatal Screening and Diagnostics
- Angiogenesis and VEGF in Cancer
- Genital Health and Disease
- Intraperitoneal and Appendiceal Malignancies
- Historical Turkish Studies
- Neurological Complications and Syndromes
- Cancer and Skin Lesions
- Reproductive System and Pregnancy
- Testicular diseases and treatments
- Gender Studies and Social Issues
- Galectins and Cancer Biology
- Renal cell carcinoma treatment
- Colorectal and Anal Carcinomas
- Pregnancy and preeclampsia studies
- Cardiac tumors and thrombi
- Music Education and Analysis
- Birth, Development, and Health
Okmeydanı Eğitim ve Araştırma Hastanesi
2019-2023
Sağlık Bilimleri Üniversitesi
2021-2022
Istanbul Eye Hospital
2022
Zübeyde Hanim Maternity Hospital
2021
Istanbul University
2013-2018
Istanbul University-Cerrahpaşa
2016-2018
Gynecologic Oncology Group
2015
The prognostic significance of isolated tumor cells (≤0.2 mm) in sentinel lymph nodes (SLNs) endometrial cancer patients is still unclear. Our aim was to assess the value with low risk who underwent SLN biopsy and did not receive adjuvant therapy. Outcomes were compared node negative patients. Patients SLNs-isolated between 2013 2019 identified from 15 centers worldwide, while Mayo Clinic, Rochester, 2018. Only (stage IA, endometrioid histology, grade 1 or 2) any therapy included. Primary...
Primary signet cell carcinoma of the cervix has been reported only in 18 cases to date.A 48-year-old woman was seen at our Gynecologic Oncology Unit, because she complained postcoital bleeding during last three months. She had 1-2 cm cervical mass, originating from endocervical canal. A biopsy revealed a ring cell-type adenocarcinoma. Suspected primary sites were excluded after gastroscopy, colonoscopy and mammography. The patient underwent laparoscopic type-3 radical hysterectomy with...
<h3>Objective</h3> The purpose of this study was to evaluate the clinicopathological characteristics and survival outcomes women with simultaneous endometrial ovarian carcinomas having same histopathologic type. <h3>Materials Methods</h3> A review medical records from 1997 2015 identified 72 patients endometrium ovary Patients synchronous primary cancers (SCEOs) were compared cancer metastasis (ECOM). Clinical pathological data obtained patients' records. Clinicopathological variables...
The purpose of this study was to investigate the outcomes and prognostic factors metastasectomy in patients with metastatic ovarian tumors from extragenital primary sites.All pathologically confirmed between January 1997 June 2015 were included study. A total 131 identified. data obtained patients' medical records. Clinicopathological features evaluated by both univariate multivariate analyses.The sites colorectal region (53.4%), stomach (26%), breast (13%). Preoperative serum CA 125 19-9...
To evaluate the incidence, diagnosis and management of GTN among 28 centers in Turkey.A retrospective study was designed to include patients attending 10-year period between January 2003 May 2013. Demographical characteristics patients, histopathological diagnosis, International Federation Gynecology Obstetrics (FIGO) anatomical prognostic scores, use single-agent multi-agent chemotherapy, surgical interventions prognosis were evaluated.From 2003-2013, there 1,173,235 deliveries 456 cases at...
The aim of this study was to investigate rates expression PTEN (phosphatase and tensin homolog deleted on chromosome 10) β-catenin their relationship with clinicopathological prognostic factors in endometrioid type endometrial cancer (EC).PTEN expressions 59 operated patients EC between January 2000 December 2008 followed-up until 2014 Cerrahpasa School Medicine, Gynecologic Oncology Division, were evaluated retrospectively. Clinical data obtained from patient files, pathological pathology...
The goal of this study was to evaluate the combination sentinel lymph node (SLN) mapping and F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) scan in detection involvement patients with endometrioid endometrial cancer (EEC).Ninety-five EEC who had preoperative PET/CT imaging underwent SLN were retrospectively analyzed. Methylene blue dye used injected cervix at 3- 9-o'clock positions (a total 4 mL). Pelvic lymphadenectomy performed on all after mapping. If...
Abstract Purpose This study aimed to evaluate trefoil factor 3 (TFF3), secreted frizzled-related protein 4 (sFRP4), reactive oxygen species modulator 1 (Romo1) and nuclear kappa B (NF-κB) as diagnostic prognostic markers of endometrial cancer (EC) ovarian (OC). Methods Thirty-one patients with EC 30 OC undergone surgical treatment were enrolled together healthy controls in a prospective study. Commercial ELISA kits determined serum TFF-3, Romo-1, NF-кB sFRP-4 concentrations. Results Serum...
Introduction. Intravenous leiomyomatosis with cardiac extension is an extremely rare uterine tumor. We report here a case of intravenous leiomyoma extending to the right atrium, diagnosed in patient having leiomyoma. Case Presentation. A 39-year-old woman no symptoms and past medical history two myomectomy operations (7 3 years previously) was admitted our clinic for routine control. detected fibroid 8 centimeters 4 small solid masses 1-2 near uterus ovaries at vaginal ultrasonography....
Objective The aim of this multicenter study was to evaluate the feasibility sentinel lymph node (SLN) mapping in clinically uterine confined endometrial cancer. Methods Patients who underwent primary surgery for cancer with an SLN algorithm were reviewed. Indocyanine green or blue dye used as a tracer. SLNs and/or suspicious nodes resected. Side specific lymphadenectomy performed when unsuccessful. ultrastaged on final pathology. Results 357 eligible patients analyzed. Median age 59 years....
Adnexal torsion can be a life-threatning condition in pregnancy, while the risk of late diagnosis is increased, second and third trimester particular. Laparoscopy an effective approach treatment adnexal torsion. However, entry to abdomen may challenging more advanced pregnancies.Herein, we report case during 20th week twin which was detorsioned laparoscopically. The woman delivered healthy infants at her 36th pregnancy.Adnexal as cause acute kept mind pregnants, even if there no predisposing...
Background: The purpose of this study was to determine the benefit tertiary cytoreductive surgery (TC) for secondary recurrent epithelial ovarian cancer (EOC), focusing on whether optimal cytoreduction has an impact disease-free survival, and certain patient characteristics could identify ideal candidates TC. Materials Methods: Retrospective analysis EOC patients undergoing TC at three Turkish institutions from May 1997 July 2014 performed. All had previously received primary followed by...
The aim of this study was to evaluate the risk factors for recurrence borderline ovarian tumours. This investigated 127 women who were finally diagnosed with epithelial Most them in stage I (83.4%). With a median follow-up 81.8 months (range: 14–205), time 22.4 3–74). Five-year recurrence-free survival (RFS) and overall (OS) rates 85.8% 97.6%, respectively. In multivariate analysis, invasive implants fertility-sparing surgery found be independent prognostic 5-year RFS. Overall, 20 patients...
Objective This study aimed to find out whether side-specific pelvic lymphadenectomy can be omitted without compromising diagnostic efficacy according “reflex frozen section” analysis of the uterus in case sentinel lymph node (SLN) mapping failure. Methods Patients who underwent surgery for endometrial cancer with an SLN algorithm were stratified as low-risk or high-risk uterine features on final pathology reports. Two models patients defined omit lymphadenectomy: strategy A included...
Abstract Background and Objectives The purpose of this study was to find out the risk factors associated with non‐sentinel lymph node metastasis determine incidence according groups in sentinel (SLN)‐positive endometrial cancer patients. Methods Patients who underwent at least bilateral pelvic lymphadenectomy after SLN mapping were retrospectively analyzed. categorized into low, intermediate, high‐intermediate, high‐risk defined by ESMO‐ESGO‐ESTRO. Results Out 395 eligible patients, 42...
"Rare cutaneous metastasis in vulvar squamous cell carcinoma without any distant organ spread." Journal of Obstetrics and Gynaecology, 36(5), pp. 692–693
Objectives: Endometrial cancer (EC) is the most common gynecological malignancy.The 18 fluorine-fluorodeoxyglucose ( F-FDG) positron emission tomography/computed tomography (PET/CT) used for initial staging, evaluating treatment response, and detecting recurrence.This study aimed to investigate diagnostic value of preoperative PET/CT in EC staging determine volumetric PET parameters that are accurate predictors histopathological tumor characteristics.Methods: Preoperative data 66 patients...
To evaluate the use of YKL-40 in discrimination between benign and malignant adnexal mass to determine its prognostic value assessing residual tumor after primary cytoreduction platinum sensitivity serous epithelial ovarian carcinoma (EOC).
This research was undertaken to identify risk factors for the involvement of sentinel lymph nodes (SLNs) in cases endometrial cancer. From February 2016 April 2021, 874 women with cancer treated SLN algorithm at 11 institutions were analyzed this retrospective study. Clinical and pathologic data reviewed, logistic regression applied predictive involvement. After exclusion 81 patients, remaining cohort 793 patients analyzed. The SLNs occurred 9.2% these (n = 73). In univariate analysis, seen...
To evaluate the clinico-pathological patient features, prognostic factors, treatment options and outcomes of peripheral nodal recurrence (PNR) endometrial cancer (EC).The data nine patients with PNR EC from two institutions were reviewed. The electronic literature was reviewed 1972 to May 2018 identify articles about in EC. Finally, 42 cases evaluated.Nineteen (45.2%) initially diagnosed either stage I or II disease, whereas 20 (47.7%) had III IV disease while stages not reported three...
The aim of this study was to evaluate the prognostic factors for and determine effect neoadjuvant chemotherapy (NACT) on oncologic outcome in stage IVB pure serous endometrial carcinoma patients who received taxane platinum. Forty-two with 2009 International Federation Gynecology Obstetrics (FIGO) uterine were enrolled from six gynecologic oncology centers a group created. had 2-year disease-free survival (DFS) 32% disease-specific (DSS) 73%. On univariate analysis; lymphadenectomy (not...