A5037365647- Functional Brain Connectivity Studies
- Immune Cell Function and Interaction
- Advanced Neuroimaging Techniques and Applications
- Viral Infectious Diseases and Gene Expression in Insects
- Neurological Complications and Syndromes
- Radiomics and Machine Learning in Medical Imaging
- Schizophrenia research and treatment
- Multiple Sclerosis Research Studies
- CAR-T cell therapy research
- Neurological disorders and treatments
- Infectious Encephalopathies and Encephalitis
- Medical Imaging and Analysis
- CRISPR and Genetic Engineering
- Pharmacological Effects and Toxicity Studies
- Intracerebral and Subarachnoid Hemorrhage Research
- RNA Interference and Gene Delivery
- Cerebrovascular and Carotid Artery Diseases
- Cerebral Venous Sinus Thrombosis
- Syphilis Diagnosis and Treatment
- T-cell and B-cell Immunology
- Cytomegalovirus and herpesvirus research
- Medical Imaging Techniques and Applications
- Polyomavirus and related diseases
- Electron Spin Resonance Studies
- AI in cancer detection
Hospital South West Jutland
2017-2023
University of Southern Denmark
2021-2023
University of Rijeka
2002-2016
Klinički Bolnički Centar Rijeka
2016
University Hospital Centre Zagreb
2008-2014
Brown University
2010
University at Buffalo, State University of New York
2008-2010
Buffalo Psychiatric Center
2010
Jacobs Institute
2010
SUNY Upstate Medical University
2010
Background Studies showed gender-associated differences in multiple sclerosis (MS) disease evolution and the of conventional magnetic resonance imaging (MRI) findings. Objective The aim this study was to investigate gender according a number nonconventional MRI measures patients with MS. Methods We examined 763 consecutive MS [499 (19.2% men) relapsing-remitting (RR), 230 (24.8% secondary-progressive, 34 (44.1% primary-progressive], 32 (21.9% clinically isolated syndrome (CIS), 101 (30.7%...
We aimed to investigate whether mild cognitive impairment (MCI) in Parkinson's disease (PD) is characterized by region-specific gray matter (GM) atrophy and explore correlations between GM cognition PD. Magnetic resonance images of 42 newly diagnosed PD patients (of which 11 had MCI) 37 normal controls were analyzed using voxel-based morphometry. Analyses comparing groups showed no regional atrophy, there significant domain test performance loss. In conclusion, does not seem be a major...
The NKG2D receptor is one of the most potent activating natural killer cell receptors involved in antiviral responses. mouse ligands MULT-1, RAE-1, and H60 are regulated by murine cytomegalovirus (MCMV) proteins m145, m152, m155, respectively. In addition, m138 protein interferes with expression both MULT-1 H60. We show here that five RAE-1 isoforms, RAE-1delta, resistant to downregulation MCMV this escape has functional importance vivo. Although m152 retained newly synthesized RAE-1delta...
The rs6265 single nucleotide polymorphism (SNP) is a genetic variation in the brain-derived neurotrophic factor (BDNF) gene wherein presence of A-allele at causes replacement valine (Val) position 66 by methionine (Met). We reported recently that Met66 allele was associated with lower brain damage as evidenced measurement gray matter (GM) volume multiple sclerosis (MS) patients. objective this study to determine voxel-wise regional GM differences between Val66Val and groups MS patients using...
Aims and Background To report an extremely rare case of Ewing's sarcoma located in the rectovaginal septum. is a highly malignant neoplasm bone, which usually occurs during childhood. Common extraosseous localizations include trunk, extremities, uterus, cervix vagina. Methods A 45-year-old woman presented to us with six-month history pain lower abdomen intercourse. Pelvic examination was performed palpable mass found. The had size 9 × 6 cm, soft tissue consistency, partially movable patient...
ABSTRACT PURPOSE To determine to what extent T1- and T2-regional lesion volumes (RLVs) contribute total and/or regional gray matter (GM) atrophy in multiple sclerosis (MS). METHODS We studied 110 (67 relapsing-remitting 43 secondary-progressive) MS patients. SABRE program was used parcel the brain into 13 regions per hemisphere. Total GM fractions (GMFs) were determined each region correct for intraregional size variability. Partial correlations associations (holding converse constant)...
The aim of this study is to report the first case simultaneous appearance cerebral venous thrombosis (CVT) and bilateral subdural hematomas (SDHs) following epidural analgesia for labor delivery point out difficulty establishing such a diagnosis in presence postpartum headache. A 26-year old primigravida with history epilepsy received delivery. Three days after uneventful spontaneous vaginal she complained about Patient responded very well pain medication oral hydration, headache was...
Abstract To present a 29‐year‐old immunocompetent patient with neurosyphilitic changes characterized by multiple acute ischemic brain strokes along significant narrowing of several large intracranial arteries. Ceftriaxone treatment for 14 days followed benzathine benzylpenicillin weekly additional 3 weeks, showed improvement in meningovascular changes.
This paper demonstrates a case of progressive multifocal leukoencephalopathy (PML) in patient with multiple myeloma (MM) treated nine different MM therapies. report contributes to the already published 16 cases PML patients MM. Additionally, this presents an analysis from United States Food and Drug Administration Adverse Event Report System database (n = 117) description demographics MM-specific Patients MM, that developed PML, were immunomodulatory drugs (97%), alkylating agents (52%),...
Internal carotid artery agenesis is a rare anomaly that can be clinically asymptomatic. Klippel-Feil syndrome skeletal malformation characterized by vertebral fusion. Presence of postaxial polydactyly suggestive an underlying syndrome.We report case 44-year-old patient with non-specific symptoms and association between these three abnormalities. Vascular anomalies were found using intracranial MR angiography multi-detector CT the supraaortic arteries.Presence single aforementioned requires...
Acute toxic leukoencephalopathy (ATL) and delayed post-hypoxic (DPHL) are two possible adverse entities related to opioid intoxication (OI), each having a distinct clinical course. While ATL shows monophasic course with gradual neurological deterioration, DPHL has biphasic We report case of along happening in young male patients OI, including their courses as well imaging characteristics comparable time intervals. Initially, both leukoencephalopathies typically show magnetic resonance...
Background: Schizophrenia is a severe illness whose clinical course characterized by various numbers of psychotic episodes (PE). The neurotoxic hypothesis (NH) schizophrenia assumes that psychosis biologically toxic. aim the study was to investigate whether patients (SP) with multiple PE have greater grey matter volume (GMV) reduction compared SP fewer PE.Subjects and methods: We enrolled 106 adult 63 healthy controls.Demographic data were collected statistically analysed for all included...
A common issue with X-ray examinations (XE) is the erroneous quality classification of XE, implying that process needs to be repeated, thus delaying diagnostic assessment XE and increasing amount radiation patient receives. The authors propose a system for automatic based on convolutional neural networks (CNN) would simplify this significantly decrease classification. data used CNN training consist 4000 knee images obtained via radiography procedure (KXE) in total, 2000 KXE labeled as...
Increasing research evidence suggests that basal ganglia are an important part of frontal-subcortical circuit which is involved not only in motor control but also affective, cognitive and executive functions. In this article, we describe the ability facial emotion recognition functioning a patient with left insula damage. The patient's to recognise emotional expressions was intact spite unilateral injury ganglia. He showed preserved intellectual function general, experienced difficulties on...
a prevalence from 0.6% to 1.2%. 2 Patients with vWD are prone complain of different bleeding episodes like mucocutaneus bleeding, menorrhagia, gastrointestinal angiodysplasia or excessive postsurgical bleeding. 1The infection hepatitis C virus (HCV) is major comorbidity in patients affected by disorders, 39% patients. 3In chronic HCV the combination therapy pegylated interferon alpha-2b and ribavirin becoming standard treatment. 4Recent studies suggested that receiving were more develop an...
Abstract Introduction Isolated unilateral hypoglossal nerve palsy is an infrequent condition that usually appears in connection to underlying disease. Rarely, the cause cannot be determined, and there no symptom remission. Case description We report two cases of male patients who developed persistent idiopathic isolated palsy. The younger patient complained involuntary movements tongue, while older dysarthria. In both cases, symptoms lasted for several weeks before initial clinical...