Chen Zhao

ORCID: 0000-0002-5832-1179
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About
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Research Areas
  • Microbial Metabolic Engineering and Bioproduction
  • Biofuel production and bioconversion
  • Enzyme Catalysis and Immobilization
  • Essential Oils and Antimicrobial Activity
  • Algal biology and biofuel production
  • Enzyme Production and Characterization
  • Protein Hydrolysis and Bioactive Peptides
  • Seaweed-derived Bioactive Compounds
  • Phytochemistry and Biological Activities
  • Microbial Metabolites in Food Biotechnology
  • Natural product bioactivities and synthesis
  • Catalysis for Biomass Conversion
  • Food Quality and Safety Studies
  • Reproductive Physiology in Livestock
  • Moringa oleifera research and applications
  • Ruminant Nutrition and Digestive Physiology
  • Ovarian function and disorders
  • Animal health and immunology
  • Plant responses to elevated CO2
  • Plant Disease Resistance and Genetics
  • Seed and Plant Biochemistry
  • Biodiesel Production and Applications
  • Pharmacological Effects of Natural Compounds
  • Natural Antidiabetic Agents Studies
  • Insect Pest Control Strategies

Qilu University of Technology
2021-2025

Shandong Academy of Sciences
2021-2025

Northwest A&F University
2016-2024

Beijing University of Agriculture
2021-2023

Shandong Food Fermentation Industry Research and Design Institute
2021-2022

Renji Hospital
2018

Shanghai Jiao Tong University
2018

Nanjing Forestry University
2010-2013

Xi'an Technological University
2008

Increasing concerns over the use of antimicrobial growth promoters in animal production has prompted need to explore natural alternatives such as phytogenic compounds and probiotics. Citrus EOs have potential be used an alternative antibiotics animals. The purpose this research was study antibacterial antioxidant activities five citrus EOs, grapefruit essential oil (GEO), sweet orange EO (SEO), bergamot (BEO), lemon (LEO) their active component d-limonene (DLEO). chemical composition...

10.3390/molecules27207044 article EN cc-by Molecules 2022-10-19

The seaweed Laminaria japonica is considered as a potentially sustainable marine resource with good nutritional and medicinal value. Saccharomyces cerevisiae two Lactiplantibacillus strains were added to the starter culture of mixed fermentation L. japonica. effects on metabolite profiles antioxidant hypoglycemic activities fermented evaluated. Untargeted metabolomics analysis showed that levels organic acids, phenolics, vitamins, unsaturated fatty acids significantly increased, whereas...

10.1016/j.lwt.2022.113122 article EN cc-by-nc-nd LWT 2022-01-19

The purpose of this study was to compare the antioxidant activity litsea cubeba oil (LCO), cinnamon (CO), anise (AO), and eucalyptus (EUC) in vitro. chemical compositions essential oils (EOs) were analyzed using gas chromatography-mass spectrometry (GC-MS). four EOs evaluated through scavenging DPPH free radicals, chelating Fe2+, hydroxyl inhibiting yolk lipid peroxidation. results showed that major compounds found LCO, CO, AO, EUC are citral (64.29%), cinnamaldehyde (84.25%), anethole...

10.3390/molecules28135051 article EN cc-by Molecules 2023-06-28

Skin aging, autonomic mobility, memory function and physical deterioration are important features of effective anti-aging treatments in slowing down these processes. The objective this research was to evaluate the protective effect Colla Corii Asini (Ejiao) Collagen Peptides (CCACPs) on D-galactose (D-gal) injection combined with UV irradiation-induced senescence mice. BY-HEALTH collagen oral solution (Bcos) used as a positive control. Behavioural experiments showed that CCACPs significantly...

10.1371/journal.pone.0317302 article EN cc-by PLoS ONE 2025-02-13

Fucoidan is a fucose-rich sulfated polysaccharide that has gained attention owing to its various biological activities. In this study, fucoidan was isolated from Saccharina japonica using an enzyme-assisted method, and antioxidant anti-hepatocarcinoma effects were evaluated. The 112.8 kDa comprising seven monosaccharides: fucose, xylose, glucuronic acid, rhamnose, glucose, mannose, galactose. main chain residues (1 → 3)-α-L-Fucp 4)-α-L-Fucp units with sulfate groups at the C-2/C-4 positions...

10.1038/s41598-025-94312-7 article EN cc-by-nc-nd Scientific Reports 2025-03-15

Background Allium fistulosum L. has good nutritional value and is cultivated worldwide as an efficacious traditional medicinal plant. Its biological activities are attributable to its phytochemicals. Nitrogen essential nutrient for plant growth development; however, the effect of nitrogen levels on level active components in this species not well understood. Methods In study, using urea fertilizer, we investigated effects different (N0, N1, N2 at 0, 130, 260 kg/ha, respectively)...

10.7717/peerj.11706 article EN cc-by PeerJ 2021-06-24

Inflammatory diseases are a major threat to public health. Natural plant essential oils (EOs) possess anti-inflammatory and anti-oxidative activities. The objective of this study was investigate the effect mode action lemon oil (LEO), its main active component, d-limonene, with different doses on intestinal inflammation mice. Sixty-four 5-week-old male balb/c mice weighing 22.0 ± 1.5 g were randomly assigned into one 8 treatments (n = 8/treatment), including normal saline group (NS),...

10.3389/fnut.2022.843096 article EN cc-by Frontiers in Nutrition 2022-06-02

Context: MOTILIPERM was prepared as a mixture of extracts three medicinal herbs [roots Morinda officinalis How (Rubiaceae), outer scales Allium cepa L. (Liliaceae) and seeds Cuscuta chinensis Lamark (Convolvulaceae)].Objective: To investigate the role reactive oxygen species (ROS)-based endoplasmic reticulum (ER) stress in rat model varicocele therapeutic efficacy this model.Materials methods: Sixty male rats were divided into five experimental groups: normal control group (CTR + vehicle),...

10.1080/13880209.2017.1421672 article EN cc-by Pharmaceutical Biology 2018-01-01

Cellulase is the one of largest contributors to high production costs lignocellulose-based biorefineries. As most widely used cellulase producer, Trichoderma reesei has two weaknesses, deficiencies in β-glucosidase and cellobiohydrolase II. This work aimed at solving this problem by simultaneous enhancement beta-exo synergism exo-exo T. increase cellulose degrading capability, i.e. enhanced co-expression gene II reesei.Enhanced using strong promoter Pcbh1 was found successful overcoming...

10.1186/s12934-019-1060-x article EN cc-by Microbial Cell Factories 2019-01-18

Inflammation caused by bacterial lipopolysaccharide (LPS) disrupts epithelial homeostasis and threatens both human animal health. Therefore, the discovery development of new anti-inflammatory drugs is urgently required. Plant-derived essential oils (EOs) have good antioxidant activities. Thus, this study aims to screen evaluate effects cinnamon oil eucalyptus on The associated evaluation indicators include body weight gain, visceral edema coefficient, superoxide dismutase (SOD), glutathione...

10.3390/molecules26237410 article EN cc-by Molecules 2021-12-06

The fermentation of food materials with suitable probiotic strains is an effective way to improve biological activities. In this study, seaweed extracts were fermented by Saccharomyces cerevisiae and Lactiplantibacillus plantarum, the hypolipidemic effects products investigated. vitro experiments suggested that have a high capacity for bile acid-binding. Additionally, significant inhibitory effect against pancreatic lipase was observed. Furthermore, in hyperlipidemic mice determined....

10.3389/fmicb.2021.772585 article EN cc-by Frontiers in Microbiology 2021-11-12

Abstract With the increased incidence and recognition, ulcerative colitis (UC) has become a global public health problem in world. Although many immunosuppressant biological drugs have been used for UC treatment, cure rate is still very low. It necessary to find some safe long-term medicine cure. Recently, Chinese traditional herb Danshen investigated treatment of UC. However, it limitation that active components are not easily absorbed by human body. Probiotics could convert macromolecules...

10.1038/s41598-021-94594-7 article EN cc-by Scientific Reports 2021-08-10

We hypothesised that adding a combination of fibrolytic and amylolytic enzymes to the diet early-lactation dairy cows would improve rumen enzyme activity bacterial diversity, promote energy metabolism, benefit milk production in cows. Twenty multiparous (90 ± 5 d) Holstein with similar body conditions were randomly allocated control (CON, n = 10) experimental (EXP, groups completely randomised single-factor design. The CON was fed only basal total mixed ration diet, EXP supplemented at 70...

10.1016/j.animal.2022.100595 article EN cc-by-nc-nd animal 2022-07-27

Background Fagopyrum dibotrys is an important wild food and feed germplasm resource. It has high nutritional medicinal value rich in natural products, including flavonoids, phenolic acids, coumarins, alkaloids. Endophytic fungi F. have emerged as valuable sources of products. However, studies on the biological activity chemical composition these endophytic remain limited. Methods In this paper, a new method to obtain active ingredients by fermentation from plants was proposed. Then...

10.7717/peerj.18529 article EN cc-by PeerJ 2024-11-18

Abstract The high production cost of cellulase is one the limitations that hinder commercialization lignocellulose‐based biorefineries. As important cellulases, Neurospora crassa not so intensively investigated as T. reesei cellulase. In this study, cbh1 gene (NCU07340) cloned from N. was expressed in Pichia pastoris under control alcohol oxidase 1 (AOX1) promotor. Six transformants with highest resistance to G418 were selected by two rounds transformant screening, among which most robust...

10.1002/btpr.2795 article EN Biotechnology Progress 2019-02-28
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