Haile Zhao

ORCID: 0000-0002-5870-062X
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About
Contact & Profiles
Research Areas
  • Land Use and Ecosystem Services
  • World Trade Organization Law
  • Global trade and economics
  • Sphingolipid Metabolism and Signaling
  • Remote Sensing in Agriculture
  • Traffic Prediction and Management Techniques
  • Plant Water Relations and Carbon Dynamics
  • Transportation Planning and Optimization
  • Urban Heat Island Mitigation
  • Urban Green Space and Health
  • Rangeland Management and Livestock Ecology
  • Urban Transport and Accessibility
  • Edible Oils Quality and Analysis
  • Microtubule and mitosis dynamics
  • Immune Response and Inflammation
  • Soil erosion and sediment transport
  • Histone Deacetylase Inhibitors Research
  • Agricultural Economics and Policy
  • Building Energy and Comfort Optimization
  • ATP Synthase and ATPases Research
  • Land Rights and Reforms
  • Financial Distress and Bankruptcy Prediction
  • Drug Transport and Resistance Mechanisms
  • Noise Effects and Management
  • Nanoplatforms for cancer theranostics

China Agricultural University
2021-2024

Inner Mongolia University
2020-2024

Ministry of Natural Resources
2022-2023

Inner Mongolia People's Hospital
2022

University of International Business and Economics
2011-2012

Biomimetic membrane materials have been widely explored and developed for drug loading tissue engineering applications due to their excellent biocompatibility abundant reaction sites. However, novel cytomembrane mimics lacking a long time. In this study, black phosphorus (BP) was used as the foundation new generation of promising its multiple similarities cytomembranes. Inspired by dual function endotoxins on membranes, we prepared BP-based mimic with controllable antibacterial ability via...

10.1021/acsami.1c15220 article EN ACS Applied Materials & Interfaces 2021-08-30

Lysophosphatidic acid (LPA) and geminin are overexpressed in ovarian cancer, increasing evidence supports their contribution to tumor development. Here, we reveal that depletion induces autophagy suppression enhances reactive oxygen species (ROS) production apoptosis of high-grade serous cancer (HGSOC) cells. Bioinformatics analysis pharmacological inhibition studies confirm LPA activates expression the early S phase HGSOC cells

10.3389/fphar.2022.1046269 article EN cc-by Frontiers in Pharmacology 2022-12-19

Geminin, an inhibitor of the DNA replication licensing factor, chromatin and factor (Cdt) 1, is essential for maintenance genomic integrity. As a multifunctional protein, geminin also involved in tumor progression, but molecular details are largely unknown. Here, we found that lysophosphatidic acid (LPA)–induced upregulation was specific to gastric cancer cells. LPA acted via receptor (LPAR) 3 matrix metalloproteinases (MMPs) signaling transactivate epidermal growth (EGFR) (Y1173) thereby...

10.3389/fphar.2021.706240 article EN cc-by Frontiers in Pharmacology 2021-09-29

The growing population and northward shifts in the center of grain production collectively contribute to arising farmland use intensity farming–pastoral ecotone Northern China (FPENC). Consequently, it poses a great threat vulnerable ecosystem FPENC. Thus, monitoring is top priority practice sustainable farming. In this study, we establish an indicator system designed evaluate Ulanqab, located central part This includes three single-year indicators (the degree coupling between effective...

10.3390/rs13214304 article EN cc-by Remote Sensing 2021-10-26

Most cities in China, especially industrial cities, are facing severe air pollution, which affects the health of residents and development cities. One most effective ways to alleviate pollution is improve urban ventilation environment; however, few studies have focused on relationship between them. The Frontal Area Index (FAI) can reflect obstructive effect buildings wind. It influenced by architectural form an attribute city itself that be used accurately measure capacity or potential city....

10.3390/rs14143348 article EN cc-by Remote Sensing 2022-07-12

Abstract Traffic congestion is one of serious problems in cities; rainfalls would exacerbate traffic congestion, and thus result huge economic losses. However, limited studies focused on how influenced its associated Based detailed hourly data, we estimated index (TCI) changed with different rainfall intensities the Beijing-Tianjin-Hebei (BTH) region, China, also explored their The results illustrated that all cities presented similar trend daily morning peak occurred 2 hours later holidays...

10.21203/rs.3.rs-1442299/v1 preprint EN cc-by Research Square (Research Square) 2022-04-13

Abstract BackgroundLysophosphatidic acid (LPA) is one of the simplest active phospholipid molecules. Binding to its receptors on cell surface, LPA initiates various intracellular signal cascades, involving in numerous biological processes, such as proliferation, migration, and apoptosis. If abnormalities occur processes production, receptor expression or transduction, it may induce certain diseases even contribute occurrence, development metastasis cancer. However, whether initiation DNA...

10.21203/rs.3.rs-79317/v1 preprint EN cc-by Research Square (Research Square) 2020-09-22
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