A5021065960- Radiopharmaceutical Chemistry and Applications
- Effects and risks of endocrine disrupting chemicals
- Prostate Cancer Treatment and Research
- Immune Response and Inflammation
- Cytokine Signaling Pathways and Interactions
- Neurological Disorders and Treatments
- Carcinogens and Genotoxicity Assessment
- Medicinal Plants and Bioactive Compounds
- Rheumatoid Arthritis Research and Therapies
- Medical Imaging Techniques and Applications
- Natural Antidiabetic Agents Studies
- Medicinal Plants and Neuroprotection
- Vitamin C and Antioxidants Research
- Curcumin's Biomedical Applications
- Cancer-related gene regulation
- interferon and immune responses
- Nuclear Receptors and Signaling
- Respiratory Support and Mechanisms
- Metabolomics and Mass Spectrometry Studies
- Natural product bioactivities and synthesis
- Airway Management and Intubation Techniques
- Phytochemistry and Biological Activities
- Chalcogenide Semiconductor Thin Films
- Mast cells and histamine
- Inflammasome and immune disorders
St Vincent's Hospital Sydney
2019-2025
Post Graduate Institute of Medical Education and Research
2025
Shree Guru Gobind Singh Tricentenary University
2024-2025
Amity University
2020-2024
Indira Gandhi Medical College
2020-2023
Manipal University Jaipur
2022
St Vincent's Hospital
2019-2022
Command Hospital
2022
National Centre for Cell Science
2021
Lovely Professional University
2020-2021
Bisphenol A (BPA), an estrogenic and endocrine disrupting agent, is widely used in manufacturing of polycarbonate plastics epoxy resins. BPA other chemicals (EDCs) act via multiple mechanisms including interference with mitochondrial functions. Mitochondria are the hub cellular energy pool hence target many EDCs. We studied perturbation activities enzymes by its possible role hepatotoxicity Wistar rats. Rats were exposed to (150 mg/kg, 250 500 mg/kg per os, for 14 days) electron transport...
177LuPSMA is an effective treatment in metastatic castrate-resistant prostate cancer with trials adopting a standardised dose interval. Adjusting intervals utilising early response biomarkers may improve patient outcomes.This study evaluated progression-free survival (PFS) and overall (OS) based on interval adjustment 24-h SPECT/CT (177Lu-SPECT) prostate-specific antigen (PSA) response.Retrospective analysis of clinical 177Lu-PSMA-I&T programme.In all, 125 men were treated 6-weekly...
18F-FDG PET/CT has low sensitivity for estrogen receptor and progesterone (ER/PR)-positive breast cancer. By contrast, gastrin-releasing peptide is overexpressed in ER/PR-positive This study assessed the diagnostic potential of 68Ga-NeoB staging or restaging metastatic human epidermal growth factor 2 (HER2)-negative Methods: Patients with HER2-negative cancer clinical suspicion disease undergoing were prospectively enrolled. All patients underwent PET/CT, addition to standard PET/CT. status...
Background:InIndia,a country with low resources, problems of lack trained staff, large number deliveries, basic facilities for monitoring foetuslead to challenges faced by treating obstetrician. Partograph though a simple tool is underused.Several factors have been implicated this and its incorrect use at all centres providing maternity care.These are knowledge,improper training,graphs non availability, wrong perceptions regarding it, huge patient number, shortage unsupportivebehaviour among...
<b>BACKGROUND:</b><sup>177</sup>Lutetium PSMA-617 (<sup>177</sup>LuPSMA-617) therapy has shown high prostate specific antigen (PSA) response rates in men with metastatic castration-resistant cancer (mCRPC). However early treatment resistance is common. This LUPIN sub-study aimed to determine the prognostic value of post-treatment quantitative PET for PSA progression free (PSA-PFS) and overall survival (OS) <sup>177</sup>LuPSMA-617 therapy. <b>METHODS:</b> 56 progressive mCRPC were enrolled...
Background: “Aurora Borealis” is a natural example of plasma visible in the universe. The northern lights, or Aurora Borealis, are stunning displays light that occur when energized particles from sun collide with Earth’s upper atmosphere. Plasma generation laboratory by dielectric barrier gains significant attention for wide range applications due to its antimicrobial, anti-inflammatory, healing, and regenerative properties. Purpose: This article highlights research on cold action mechanisms...
The in vitro micronucleus test is a well-known for the screening of genotoxic compounds. However until now, most studies have been performed on either human peripheral lymphocytes or established cancer cell lines. This study provides mesenchymal stem cells as an alternative to conventional test. We grew umbilical cord (UC-MSCs) coverslips eliminating cumbersome technique involving hypotonic treatment, fixation and preparing smears required suspension culture (lymphocytes). background...
Abstract BACKGROUND The plant Arnica montana is used in folk medicine to alleviate pain, inflammation and swelling of muscles joints associated with rheumatoid arthritis other inflammatory conditions. present study aimed investigate the therapeutic effects mechanism action A. flower methanol extract ( AMME ) against both oxidative stress a collagen‐induced CIA rat model. RESULTS Oral administration was found reduce clinical signs improve histological radiological status hind limb joints....
Bisphenol A (BPA) is known for endocrine disrupting activity. In order to replace BPA, a number of bisphenol analogues have been designed. However, their activity profile poorly described and little information exists about potential interactions with nuclear receptors. An understanding such interaction may unravel mechanism molecular action provide valuable inputs risk assessment. BPA binds activates peroxisome proliferator-activated receptors (PPARs) retinoid X (RXRs) which act as...
In view of the overall health impact NIDDM, inventers understand necessity improving glycemic control in adults with type 2 diabetes. BGR-34 provides an effective treatment option for diabetes who have been inadequately controlled on lifestyle or without other oral hypoglycemic agents (OHGAs) such as metformin, sulfonylurea, a glitazones. is appropriate to consider addition managed care drug formulary. Treatment produced clinically relevant and statistically significant reductions all three...
Objective: The pathogenesis of diabetic cardiomyopathy (DCM) is complex, and the therapeutic options available to treat DCM are limited. present study was designed investigate effect Aegle marmelos (L.) Correa (Rutaceae) leaf extract on early stage in alloxan-induced rats.Methods: Diabetes induced Wistar rats (150–200 g) by injecting alloxan (150 mg kg−1; i.p.). Ethanol A. leaves administered at varying doses (100, 200, 400 kg−1) tolbutamide (100 as standard. Fasting blood glucose (FBG),...
Tie2 is a receptor tyrosine kinase that essential for the development and maintenance of blood vessels through binding soluble ligands angiopoietin 1 (Ang1) 2 (Ang2). Ang1 constitutively produced by perivascular cells protective adult vasculature. Ang2 plays an important role in vessel formation normally expressed during development. However, its re-expression disease states, including cancer sepsis, results destabilization contributing to pathology these conditions. thus attractive...