A5070981650- Environmental Toxicology and Ecotoxicology
- Effects and risks of endocrine disrupting chemicals
- Pesticide Exposure and Toxicity
- Chemotherapy-induced organ toxicity mitigation
- Carcinogens and Genotoxicity Assessment
- Trace Elements in Health
- Drug-Induced Hepatotoxicity and Protection
- Mycotoxins in Agriculture and Food
- Reproductive biology and impacts on aquatic species
- Glutathione Transferases and Polymorphisms
- Toxic Organic Pollutants Impact
- Phytochemistry and biological activity of medicinal plants
- Heavy Metal Exposure and Toxicity
- Immunotoxicology and immune responses
- Genomics, phytochemicals, and oxidative stress
- Neuroscience and Neuropharmacology Research
- Marine Biology and Environmental Chemistry
- Arsenic contamination and mitigation
- Physiological and biochemical adaptations
- Reproductive System and Pregnancy
- Aquaculture disease management and microbiota
- Tea Polyphenols and Effects
- Free Radicals and Antioxidants
- Science, Research, and Medicine
- Immunotherapy and Immune Responses
Jamia Hamdard
2016-2025
Hamdard University
2003-2025
Translational Research Institute
2013
Hanyang University
2007-2009
University of California, Riverside
2008
University of Plymouth
2004
Indian Institute of Toxicology Research
1990-1995
Bose Institute
1993-1994
Bisphenol A (BPA), an estrogenic and endocrine disrupting agent, is widely used in manufacturing of polycarbonate plastics epoxy resins. BPA other chemicals (EDCs) act via multiple mechanisms including interference with mitochondrial functions. Mitochondria are the hub cellular energy pool hence target many EDCs. We studied perturbation activities enzymes by its possible role hepatotoxicity Wistar rats. Rats were exposed to (150 mg/kg, 250 500 mg/kg per os, for 14 days) electron transport...
Walnut (Juglans regia L.) is extensively used in traditional systems of medicine for treatment various ailments. It described as an anticancer, tonic, blood purifier and detoxifier agent. The present study was undertaken to investigate modulatory effects walnut extract on the toxicity anticancer drug, cyclophosphamide (CP) with special reference protection against disruption drug metabolizing antioxidant enzymes. Plant extract+CP group animals showed restoration level cytochrome P450 (CYP)...
Abstract: Tamoxifen is a selective oestrogen receptor modulator widely used in the treatment of breast cancer. potentially affects mitochondrial functions as it acts an uncoupling agent and powerful inhibitor electron transport chain. There concern for deleterious effects tamoxifen. Taurine known to have membrane stabilizing antioxidant properties. We studied effect taurine pre‐treatment on toxicity tamoxifen mouse liver mitochondria focusing specifically redox cycle biomarkers. caused...
Context: Chemotherapy has long been the keystone of cancer regimen, and comprehensive research done on development more potent less toxic anti-cancer agents. Cisplatin (CP) is a extensively used chemotherapeutic agent. There paucity literature involving role mitochondria in mediating CP-induced hepatic toxicity, its underlying mechanism remains unclear. Oxidative stress well-established biomarker mitochondrial toxicity. Objective: This study evaluates dose-dependent effects mitotoxicity...
Cyclophosphamide (CP) is one of the most popular alkylating anticancer drugs in spite its toxic side effects including immunotoxicity, hematotoxicity, mutagenicity and a host others. The present study was undertaken to assess protective total aqueous extract medicinal plant, Indian gooseberry (Emblica officinalis Gaertn.) mice treated with CP. These were studied on immunological parameters kidney liver antioxidants. Plant treatment at dose 100 mg/kg body weight per os (p.o.) for 10 days...
Abstract Marine copepods have recently been recognized as important organisms in ecotoxicity testing for regulatory purposes. The harpacticoid copepod Tigriopus japonicus has a wide geographical distribution along the coast Western Pacific including Japan, South Korea, Taiwan, and Hong Kong. This study evaluated acute toxicity sensitivity profile of against 12 common toxic substances six endocrine disrupting chemicals (EDCs), three biocides trace metals. Through standard test procedures,...