A5061405691- Radiopharmaceutical Chemistry and Applications
- Thyroid Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Cancer Immunotherapy and Biomarkers
- Thyroid Disorders and Treatments
- Medical Imaging Techniques and Applications
- Orthopedic Infections and Treatments
- Thyroid and Parathyroid Surgery
- Prostate Cancer Diagnosis and Treatment
- Bone health and treatments
- Neuroendocrine Tumor Research Advances
- Cardiac Imaging and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Head and Neck Anomalies
- Colorectal and Anal Carcinomas
- Immunotherapy and Immune Responses
- Medical Imaging and Pathology Studies
- Pituitary Gland Disorders and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Ophthalmology and Eye Disorders
- Pediatric Urology and Nephrology Studies
- Lung Cancer Treatments and Mutations
- Lymphoma Diagnosis and Treatment
- Infective Endocarditis Diagnosis and Management
- Neuroblastoma Research and Treatments
Garvan Institute of Medical Research
2023-2025
St Vincent's Hospital Sydney
2023-2025
St Vincent's Clinic
2023-2025
UNSW Sydney
2023-2025
Theranostics (New Zealand)
2025
St. Vincent's Hospital
2025
St Vincent's Hospital
2025
Saint Vincent's Catholic Medical Center
2025
St. Vincent's Birmingham
2025
Peter MacCallum Cancer Centre
2022-2024
Synthetic somatostatin analogs have been posed as a potential source of error in receptor imaging through interference with tumor detection; however, experimental models and clinical studies shown complex mechanism the effect octreotide on tumors. The aim this study was to assess whether <sup>68</sup>Ga-DOTATATE uptake before treatment long-acting differs from that after treatment. <b>Methods:</b> Thirty patients (15 men; age [mean ± SD], 64.6 13.4 y) who had intermediately differentiated...
Multiparametric magnetic resonance imaging (mpMRI) has an established role for the diagnosis of clinically significant prostate cancer (sPCa). The PRIMARY trial demonstrated that [
<sup>177</sup>Lu-PSMA therapy is an effective treatment in patients with metastatic castration-resistant prostate cancer. SUV<sub>mean</sub> a valuable screening biomarker to assess the suitability for but requires quantitative software. This study aims develop simple, clinically applicable prostate-specific membrane antigen PET/CT score that encompasses elements of without requiring additional quantification. <b>Methods:</b> Datasets from ethics-approved trials cancer after androgen...
18F-FDG PET/CT has low sensitivity for estrogen receptor and progesterone (ER/PR)-positive breast cancer. By contrast, gastrin-releasing peptide is overexpressed in ER/PR-positive This study assessed the diagnostic potential of 68Ga-NeoB staging or restaging metastatic human epidermal growth factor 2 (HER2)-negative Methods: Patients with HER2-negative cancer clinical suspicion disease undergoing were prospectively enrolled. All patients underwent PET/CT, addition to standard PET/CT. status...
<title>Abstract</title> <bold>Background </bold>Prostate-specific membrane antigen (PSMA) receptor expression alters in response to androgen blockade metastatic castrate resistant prostate cancer (mCRPC). The ENZA-p trial (ANZUP 1901) demonstrated that the addition of [<sup>177</sup>Lu]Lu-PSMA-617 enzalutamide improved overall survival (OS) mCRPC. In this preplanned imaging substudy, we evaluated frequency and clinical significance early changes PSMA-PET standardised uptake value (SUV) mean...
Immunotherapy using programmed death-1 blockers is a promising modality for non–small cell lung cancer (NSCLC). Therefore, defining the most accurate response criteria immunotherapy monitoring of great importance in patient management. This study aimed to compare correlation between survival outcome and assessment by PERCIST, version 1.0; immunotherapy-modified PERCIST (imPERCIST); RECIST, 1.1; RECIST (iRECIST) NSCLC patients. <b>Methods:</b> Seventy-two patients with who were treated...
Hip prosthesis implantation has witnessed a significant increase in recent years. Despite the advantages of this surgical procedure, it some complications, most serious which is prosthetic infection. This study was conducted to investigate feasibility 99mTc-UBI scintigraphy detection infectious foci painful hip prosthesis. UBI (Ubiquicidin 29-41) an antimicrobial peptide fragment with ability target bacterial colony directly.34 patients, aged 20-79 years, were included. scan and three phase...
Involvement of the skeleton can cause an excruciating pain in two-thirds terminal patients with a history malignancy. Due to several limitations other therapies, such as analgesics, bisphosphonates, chemotherapy, hormonal therapy and external beam radiotherapy; bone-seeking radiopharmaceuticals have important role palliation from bone metastases. Although these kinds therapies many advantages including ability treat multiple sites tumoral involvement simultaneously, no significant...
We report on a 59-year-old female patient with an infected vascular graft investigated 18F FDG-PET/CT. The first of two studies showed FDG activity in the left deltoid and ipsilateral axillary lymph nodes explained by influenza vaccination day prior. second FDG-PET/CT multiple FDG-avid both sides diaphragm without tracer accumulation at site. Three months later CT was negative for lymphadenopathy within chest or abdominal region. Although is potential source false positive results PET...
The coronavirus pandemic caused by SARS-CoV-2 commenced in late 2019, and global wide vaccination appears to be the only reasonable solution fight this dreadful virus. There are two main types of COVID-19 immunization using viral vector mRNA-based vaccines. However, impact each type on 18F-FDG PET/CT needs accurately assessed. This study aimed compare features these vaccines.A total 188 patients referred for with a recent history either BioNTech/Pfizer or AstraZeneca vaccination, control...
Background: Accurate diagnosis of myocardial infarction (MI) is paramount importance in patient management, which necessitates the development efficient and accurate diagnostic methods. Q wave not present all patients with MI, its prevalence declining. Recently, fragmented QRS (fQRS) complex has been introduced as a marker prior MI. Aim: To investigate value fQRS compared to wave. Methods: We included 500 consecutive known or suspected coronary artery disease who underwent two days gated...
Abstract Background PSMA PET/CT is a predictive and prognostic biomarker for determining response to [ 177 Lu]Lu-PSMA-617 in patients with metastatic castration resistant prostate cancer (mCRPC). Thresholds defined date may not be generalizable newer image reconstruction algorithms. Bayesian penalized likelihood (BPL) algorithm novel that improve contrast whilst preventing introduction of noise. The aim this study compare the quantitative parameters obtained using BPL Ordered Subset...
Despite a high detection rate of
The differentiation of osteomyelitis from bone tumors is great importance in clinical decision-making; however, the features both and are noncontributory. Tc-ubiquicidin scintigraphy a new promising method with ability to specifically localize infection site by bacterial cell membrane binding. This study aimed evaluate this radiopeptide for these two entities.Thirty consecutive patients (mean age=20.9 years) suspected having either or tumor were included prospective study. A Tc-UBI scan was...
Ectopic thyroid tissue results from abnormal embryologic development and migration of the gland. True malignant transformation in ectopic is extremely rare always diagnosed after surgical excision lesion by pathology examinations. There are well-documented cases cancer while primary tumoral occurs orthotopic thyroid, but only PTC without any evidence occult or cervical lymph nodes have been reported. We report on a 39 year old woman who was operated for mediastinal mass. The initial...
Sagliker syndrome is a rare form of renal osteodystrophy resulted from untreated secondary hyperparathyroidism. It described by severe skeletal deformities, high level PTH in patients with chronic failure, and deformed face. This paper reports 44-year-old male patient the mentioned characteristics. In addition to unique clinical features, levels ALP hormones encouraged us search for syndrome-like disease, which clinically paraclinically matched syndrome. case highlights importance...
Purpose The study aims to define the effect of different dose strategies on ophthalmic complications in patients with Graves’ disease (GD). Methods All GD and no or inactive ophthalmopathy (clinical activity score; CAS < 3) underwent Snellen chart examination, measurement proptosis, thyroid volume, radioactive iodine uptake, randomized into 1 3 groups. In group 1, all received fixed low (FLD) 259 MBq 131 I, whereas 2, high (FHD) 555 MBq, 3, calculated (CD) was administered deliver 5.55...