A5062275253- Magnesium Alloys: Properties and Applications
- Aluminum Alloys Composites Properties
- Hydrogen Storage and Materials
- Bone Tissue Engineering Materials
- Corrosion Behavior and Inhibition
- Orthopaedic implants and arthroplasty
- Dental Implant Techniques and Outcomes
- Magnesium in Health and Disease
- Bone fractures and treatments
- Polymer Surface Interaction Studies
- Total Knee Arthroplasty Outcomes
- Boron Compounds in Chemistry
- Microfluidic and Capillary Electrophoresis Applications
- Diatoms and Algae Research
- Advanced Materials and Mechanics
- Titanium Alloys Microstructure and Properties
- Microstructure and mechanical properties
- Diabetes Management and Research
- Global Politics and Economy
- Radioactive element chemistry and processing
- TGF-β signaling in diseases
- Orthopedic Infections and Treatments
- Radiopharmaceutical Chemistry and Applications
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Surface Modification and Superhydrophobicity
Medical University of Graz
2011-2021
University of Graz
2012-2014
National University of Singapore
2013
Hospital Universitario Son Espases
2013
Sabancı Üniversitesi
2013
Nuffield Orthopaedic Centre
2013
Temple Street Children's University Hospital
2013
Marmara University
2013
Biodegradable materials are under investigation due to their promising properties for biomedical applications as implant material. In the present study, two binary magnesium (Mg) alloys (Mg2Ag and Mg10Gd) pure Mg (99.99%) were used in order compare degradation performance of vitro vivo conditions. analysis cell distribution viability was performed on discs Mg, Mg2Ag Mg10Gd. The results verified viable pre-osteoblast cells all three no obvious toxic effect within first weeks. rates conditions...
We report on the long-term effects of degrading magnesium implants bone tissue in a growing rat skeleton using continuous vivo micro-Computed Tomography, histological staining and Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS). Two different alloys—one rapidly (ZX50) one slowly (WZ21)—were used to evaluate response distribution released Mg Y ions femur male Sprague-Dawley rats. Regardless whether alloy degrades or slowly, we found that recovers restitutio ad integrum...
The purpose of this study was to compare short term in vitro and vivo biodegradation studies with low purity Mg (> 99.94 %), Mg-10Gd Mg-2Ag designed for biodegradable implant applications.Three testing conditions were applied, using (i) phosphate buffered saline (PBS), (ii) Hank's balanced salt solution (HBSS) (iii) Dulbecco's modified eagle medium (DMEM) 5 % CO 2 under sterile conditions.Gas evolution mass loss (ML) assessed, as well the degradation layer, by elemental mapping scanning...
The nanostructural adaptation of bone is crucial for its biocompatibility with orthopedic implants. nanostructure also determines mechanical properties and performance. However, the bone's temporal spatial nanoadaptation around degrading implants remains largely unknown. Here, we present insights into this important by applying scanning electron microscopy, elemental analysis, small-angle X-ray scattering tensor tomography (SASTT). We extend novel SASTT reconstruction method provide a 3D...
The growth plate at the end of long bones is cartilaginous organ responsible for longitudinal bone in children. Trauma to plate, i.e. fractures, can severely impair growth, leading disorders due destruction epiphyseal circulation and formation a bridge. From clinical experience it known that some patients this bridge eventually disappears during process. However, molecular mechanisms involved dissolution have not been clarified yet. aim study was investigate spatial temporal protein level...
Owing to the complex influences of several experimental conditions on in vitro alteration blood, there is still a lack viable tests and methods for blood compatibility evaluation biomaterials. The aim this research was study new approach haemocompatibility assessment differently modified PET surfaces using quartz crystal microbalance with dissipation unit (QCM-D) technique measure mass increase caused by clot formation under physiological conditions. For purpose some most frequently applied...
LA-ICP-MS data were spatially referenced to the respective microscope images investigate biodegradation of Mg alloys in bone tissue.
Abstract Bioresorbable magnesium materials are widely investigated because of their promising properties as orthopedic devices. Pure (99.99%) and two binary alloys (Mg2Ag Mg10Gd) were used to investigate the degradation behavior, bone adherence bone-implant interface mechanics these in growing Sprague-Dawley
The extracorporeal transport of glucose was studied to determine the dialyzer mass transfer coefficient K(0)A for in whole blood under conditions delivery and removal. Glucose removed from or delivered using glucose-free dialysate with a concentration 200 mg/dl (11.1 mmol/L). FX8 dialyzers (Fresenius Medical Care, Bad Homburg, Germany) were at constant flow Q(d) (500 ml/min) variable flows Q(b) (200, 300, 400 countercurrent series laboratory bench studies. clearance K(d) distribution volume...
Event Abstract Back to Pre-clinical characterization of RE-free bioresorbable magnesium screws in a growing sheep model Johannes Eichler1, Stefan F. Fischerauer2, Leopold Berger3, Elisabeth Martinelli1, Martina Cihova4, Tanja Kraus5, Jörg Löffler4 and Annelie M. Weinberg1 1 Medical University Graz, Department Orthopaedics, Austria 2 Trauma Surgery, 3 TU Wien, Institute Building Construction, 4 ETH Zurich, Laboratory Metal Physics Technology, Materials, Switzerland 5 Paediatric Introduction:...
Event Abstract Back to In-vivo comparison of chemically polished vs. unpolished magnesium-based screws in ovine tibiae Leopold Berger1, Johannes Eichler2, Martina Cihova3, Elisabeth Martinelli2, Claudia Kleinhans2, Jörg Löffler3 and Annelie-Martina Weinberg2 1 TU Wien, Institute for Building Construction Technology, Austria 2 Medical University Graz, Department Orthopaedic Surgery, 3 ETH Zurich, Laboratory Metal Physics Materials, Switzerland Introduction: Magnesium (Mg) its alloys possess...