A5090974518- Advanced Radiotherapy Techniques
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Endometrial and Cervical Cancer Treatments
- Brain Metastases and Treatment
- Lung Cancer Diagnosis and Treatment
- Ovarian cancer diagnosis and treatment
- Radiation Dose and Imaging
- Radiation Therapy and Dosimetry
- Medical Imaging Techniques and Applications
- Cervical Cancer and HPV Research
- Uterine Myomas and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Cancer Genomics and Diagnostics
- Lung Cancer Research Studies
- Management of metastatic bone disease
- AI in cancer detection
- Hepatocellular Carcinoma Treatment and Prognosis
- Regulation of Appetite and Obesity
- Head and Neck Cancer Studies
- Dental Anxiety and Anesthesia Techniques
- Optical Systems and Laser Technology
- Natural Products and Biological Research
- Atherosclerosis and Cardiovascular Diseases
- Cancer Cells and Metastasis
Inha University Hospital
2012-2025
Inha University
2008-2019
Dongguk University
2007
Chosun University
2002
This study aimed to develop a hybrid model combining radiomics and deep learning features derived from computed tomography (CT) images classify histological subtypes of non-small cell lung cancer (NSCLC). We analyzed CT 235 patients with NSCLC, including 110 adenocarcinoma (ADC) 112 squamous carcinoma (SCC). The dataset was split into training set (75%) test (25%). External validation conducted using the NSCLC-Radiomics database, comprising 24 each ADC SCC. A total 1409 8192 underwent...
To evaluate the patterns of tumor shape and to compare volume derived from simple diameter-based ellipsoid measurement with that tracing entire contour using region interest (ROI)-based 3D volumetry respect prediction outcome in cervical cancer patients treated concurrent chemotherapy radiotherapy.Magnetic resonance imaging was performed 98 (stage IB-IIIB). The classified into two categories: non-ellipsoid shape. ROI-based each magnetic slice on work station. For surrogate "ellipsoid...
Abstract Medium chain fatty acid (MCFA) escapes the formation of chylomicrons in small intestine, resulting energy expenditure through beta‐oxidation. Diacylglycerol (DAG) is susceptible to oxidation rather than being stored adipose tissue. This study was conducted verify effect MCE‐DAG oil on body fat mass vivo . Male C57BL/6 mice were randomly assigned four groups ( n = 12) as follows: (1) normal diet (18% kcal from fat), (2) canola a control (40% oil), (3) MCE‐DAG10 (10% + 30% and (4)...
We investigated the prognostic significance of changes in primary tumor volume and serum squamous cell carcinoma antigen (SCC-ag) levels during radiation therapy (RT) patients with cervical cancer.We conducted a review 40 treated RT. All received external beam RT intracavitary brachytherapy. The were measured pre-RT mid-RT. Overall survival (OS) progression free (PFS) estimated, possible factors for analyzed.The correlation coefficient between reduction rate (pTVRR) all was 0.550 (P <...
We report our experience with Cyberknife to deliver hypofractionated stereotactic body radiotherapy (SBRT) boost combined whole pelvis (WPRT) patients intermediate- high-risk prostate cancer.From March 2008 July 2014, 39 newly diagnosed, and (National Comprehensive Cancer Network definition) localized cancer were treated WPRT SBRT boost. The dose was 45 Gy (25 fractions of 1.8 Gy) the 21 (3 7 Gy). No one received androgen deprivation therapy before biochemical relapse. acute late toxicities...
This study aims to evaluate the usage of brain metastases (BM) tumor volume and sphericity as prognostic factors in local control (LC) after stereotactic radiosurgery (SRS) for limited number (1-4) BM from nonsmall cell lung cancer (NSCLC).We retrospectively reviewed 80 patients, with 141 BM, who were treated SRS 2012 2017. Local failure was defined an increase lesion size SRS. LC overall survival (OS) estimated using Kaplan-Meier method. The Cox proportional hazards model used univariate...
Stereotactic body radiotherapy (SBRT) has emerged as an effective treatment for localized prostate cancer. However, prostate-specific antigen (PSA) kinetics after SBRT not been well characterized. The purpose of the current study is to assess PSA low- and intermediate-risk cancer patients treated with using Cyberknife both monotherapy boost whole pelvic (WPRT) in absence androgen deprivation therapy.A total 61 intermediated-risk (36.25 Gy 5 fractions 32 patients) (21 3 29 combined WPRT (45...
Aim Stereotactic body radiotherapy (SBRT) has emerged as an effective treatment for localized prostate cancer. However, specific antigen (PSA) kinetics after SBRT not been well characterized. The objective of the current study is to analyze rate PSA decline and nadir following boost whole pelvis (WPRT) in intermediate- high-risk Methods From March 2008 July 2014, 42 patients newly diagnosed, (NCCN definition) cancer were treated with using Cyberknife WPRT. dose was 45 Gy (25 fractions 1.8...
Purpose Stereotactic body radiotherapy (SBRT) takes advantage of low α/β ratio prostate cancer to deliver a large dose in few fractions. We examined clinical outcomes SBRT using CyberKnife for the treatment low- and intermediate-risk cancer. Materials Methods This study was based on retrospective analysis 33 patients treated with localized (27.3% low-risk 72.7% intermediate-risk). Total 36.25 Gy 5 fractions 7.25 were administered. The acute late toxicities recorded Radiation Therapy Oncology...
The purpose of this study was to compare the prostate-specific antigen (PSA) kinetics between stereotactic body radiotherapy (SBRT) using Cyberknife and conventionally fractionated external beam (CF-EBRT) in low- intermediate-risk prostate cancer.A total 69 patients with cancer were enrolled. Thirty-four treated SBRT (36.25 Gy five fractions) 35 CF-EBRT (70.2-75.6 39-42 fractions). PSA nadir, rate decline biochemical failure (BCF) free survival calculated compared.With a median follow-up...
Abstract Aim: The aim is to evaluate the prognostic value of tumor diameter, volume and pelvic lymph node status assessed by magnetic resonance imaging (MRI) in patients with uterine cervical carcinoma treated concurrent chemotherapy radiotherapy. Methods: Ninety‐eight diagnosed stage IB IIIB were entered into study. Tumor diameter was evaluated T2‐weighted image. calculated equation (volume = width × length height π/6) as an ellipsoid approximation. Univariate multivariate analyses...
The prognostic value of metabolic parameters using 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) has not been established for early non-small cell lung cancer (NSCLC). Accordingly, the authors investigated in terms failure patterns patients with NSCLC who underwent stereotactic body radiation therapy (SBRT).Data from 35 Stage I SBRT CyberKnife and received pretreatment FDG PET/CT between 2008 2016 were retrospectively reviewed. Maximum standardized...
Stereotactic body radiotherapy (SBRT) has emerged as an effective treatment for localized prostate cancer. The purpose of this study was to compare the prostate-specific antigen (PSA) kinetics between conventionally fractionated external beam (CF-EBRT) and SBRT boost after whole pelvis EBRT (WP-EBRT) in A total 77 patients with cancer [T-stage, T1–T3; Gleason score (GS) 5–9; PSA < 20 ng/mL] were enrolled. 35 treated (21 Gy 3 fractions) WP-EBRT 42 CF-EBRT (45 25.2–30.6 1.8-Gy fractions)....
We analyzed clinical results of CyberKnife (CK)-based stereotactic radiosurgery (SRS) or fractionated radiotherapy (FSRT) in older patients (age ≥65 years) affected by brain metastases (BM) from non-small cell lung cancer (NSCLC). Forty-three with 92 BM were treated CK-based SRS/FSRT at our institution between 2009 and 2019. The end-point was overall survival (OS). Univariate multivariate analyses performed to identify the prognostic factors influencing OS. in-field local control (IFLC)...
We conducted a prospective phase II study on whether extended-field irradiation (EFI) confers survival benefits depending hypoxic markers in locally advanced uterine cervical cancer (LAUCC). RNA-seq was performed to identify immune and gene signatures. A total of 288 patients were randomized either EFI or pelvic radiotherapy (PRT). All completed chemoradiotherapy. Overall, significantly higher 5-year para-aortic recurrence free (PARFS) rate occurred (97.6%) than PRT group (87.2%), with...
Accelerated partial breast irradiation (APBI) is a new treatment delivery technique that decreases overall time by using higher fractional doses than conventional fractionation. Here, quantitative analysis study of CyberKnife-based APBI was performed on 10 patients with left-sided cancer who had already finished at the Inha University Hospital. Dosimetric parameters for four kinds plans (3D-CRT, IMRT, VMAT, and CyberKnife) were analyzed compared constraints in NSABP B39/RTOG 0413 protocol...
Purpose This study was designed to evaluate the dosimetric performance of Mobius3D by comparison with an aSi-based electronic portal imaging device (EPID) and Octavius 4D, which are conventionally used for patient-specific prescription dose verification. Methods The conducted using nine patients who were treated volumetric modulated arc therapy. To feasibility verification, we compared QA results EPID 4D verification methods. first phantom dose, second gamma index analysis. Results...
Stereotactic radiosurgery (SRS) or fractionated stereotactic radiotherapy (FSRT) are increasingly used as initial therapies for brain metastases (BM).We aimed to assess the outcomes of SRS/FSRT in patients aged 65 years who had 1-10 BM from non-small cell lung cancer (NSCLC). Materials and MethodsWe retrospectively reviewed 91 elderly NSCLC with 222 were treated at two institutions between 2010 2020.The primary endpoint was overall survival (OS) after SRS/FSRT.In addition, in-field local...
Introduction: The goal of this study was to evaluate the efficacy and safety high-dose stereotactic body radiation therapy (SBRT) with an extended (48 h or more) interfraction interval for hepatocellular carcinoma (HCC) ≤5 cm in size after incomplete response transarterial chemoembolization (TACE). Methods: This multicenter prospective included 54 patients inoperable HCC between July 2012 June 2015. A total SBRT dose 60 Gy 3 fractions administered within 14 days ≥48-h who showed 1–5 sessions...
The dosimetry of very small fields is challenging for several reasons including a lack lateral electronic equilibrium, large dose gradients, and the size detector in respect to field size. objective this work was evaluate suitability new commercial synthetic diamond detector, namely, PTW 60019 microDiamond, cyberknife photon beams 6 different collimator (from 5 mm 30 mm). Measurements included linearity, rate dependence, output factors (OF), percentage depth doses (PDD) off center ratio...