A5011872258- Glaucoma and retinal disorders
- Antimicrobial agents and applications
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Chemistry and Chemical Engineering
- Hepatitis Viruses Studies and Epidemiology
- Environmental Chemistry and Analysis
- Liver Disease and Transplantation
- Phenothiazines and Benzothiazines Synthesis and Activities
- Tuberculosis Research and Epidemiology
- Cholinesterase and Neurodegenerative Diseases
- COVID-19 Pandemic Impacts
- Odor and Emission Control Technologies
- Bacterial biofilms and quorum sensing
- Systemic Lupus Erythematosus Research
- Digestive system and related health
- Lipid metabolism and disorders
- COVID-19 and Mental Health
- Medicine and Dermatology Studies History
- RNA modifications and cancer
- Mycobacterium research and diagnosis
- COVID-19 epidemiological studies
- Pediatric health and respiratory diseases
- Chemical Reaction Mechanisms
Yaroslav-the-Wise Novgorod State University
2024
University Hospital Hradec Králové
2020-2024
University of South Bohemia in České Budějovice
2024
Medizinische Hochschule Hannover
2011-2023
Essen University Hospital
2023
University of Defence
2020-2021
An increasing microbial resistance to known antibiotics raises a demand for new antimicrobials. In this study the antimicrobial properties of series N-Alkylpyridinium quaternary ammonium compounds (QACs) with varying alkyl chain lengths were evaluated several nosocomial pathogens. The chemical identities QACs determined by NMR, LC-MS, and HRMS. All planktonic bacteria tested susceptible as MIC MBC assays. effect was most pronounced against Staphylococcus aureus clinical isolates. Live/dead...
Benzoxonium chloride belongs to the group of quaternary ammonium salts, which have been widely used for decades as disinfectants because their high efficacy, low toxicity, and thermal stability. In this study, we prepared C10-C18 set benzoxonium-like salts evaluate effect chemical biological decontamination capabilities. particular, biocidal activity against a panel bacterial strains including Staphylococcus aureus in biofilm form was screened. addition, most promising compounds were...
TLR are known as the main receptors on surface of innate immune cells and involved in training these cells. A plasmid containing agonist gene, HSPA14, was obtained to create recombinant mycobacterial strains expressing trained immunity activators. Mycobacteria were transformed by this plasmid, cell lysates analyzed using western blot.
Many biological agents are epidemic or pandemic in nature (Ebola 2013, Spanish influenza 1918, Russian 1989, SARS-CoV-2 2019).Recognising the onset of spread epidemics and pandemics remains a major challenge even 21 st century despite technologies scientific knowledge at our disposal, as is successful management such situations.The reason concerns existence diversity laws that govern it, which very difficult to predict virtually uncontrollable.It gradually becoming apparent current causes...
qHBsAg has been show to predict response interferon alfa but may also be useful dissect the phase of HBV-infection. The aim this study was analyze if is for prediction HBsAg loss during NUC therapy. quantified in 126 patients with chronic 95 received therapy NUCs and were followed 6–107 months. 31 not receiving observed 36–48 We further analyzed serum cytokines by CBA find additional markers loss. Six on achieved Patients had higher baseline ALT IP-10 levels suggesting ongoing immune...
ЦЕЛЬ: оценить результаты проведенных молекулярно-генетических исследований (МГИ) у детей с кли-
 ническими данными, указывающими на возможные моногенные формы сахарного диабета (СД).
 МАТЕРИАЛЫ И МЕТОДЫ: выполнен ретроспективный анализ клинического материала 10 осо-
 бенностями манифестации и течения СД, которые позволили заподозрить моногенную форму заболевания.
 Основанием для проведения МГИ в одном случае был дебют СД неонатальном периоде; один пациент
 имел...
Einleitung und Ziele Die Leberzirrhose kann zu einer portalen Hypertension assoziierten Komplikationen, wie der Bildung von Aszites Varizen(-blutungen), führen. Einschränkungen körperlichen mentalen Gesundheit beeinflussen die Patient:innen empfundene Lebensqualität. Ein transjugulärer intrahepatischer portosystemischer Shunt (TIPS) den Druck effektiv senken. In dieser Beobachtungsstudie ist es unser Ziel, Auswirkungen eines TIPS auf Lebensqualität (Quality of Life; QoL) untersuchen.
PURPOSE: To study efficacy and safety of endoscopic laser cycloplasty in treatment patients with angle-closure glaucoma plateau iris. METHODS: The included 15 (23 eyes) iris, 13 women, 2 men. Mild was diagnosed 24.7% cases; moderate — 34.8 %; advanced 30.4 %. Mean age 69.1±8.7 years. Intraocular pressure (IOP) level before surgery medical therapy ranged from 17 to 30 mm Hg (mean 22±3.4 Hg). number hypotensive instillations used by the 3.1±1.8. During postoperative period all underwent...
The article is a review of Russian and foreign literature on the problem angle-closure glaucoma with plateau iris, methods its diagnostics treatment. More than 80 sources about problems treatment (PACG) iris were analyzed. There are differences in classification this disease practice, namely differentiation configuration syndrome, which influences choice analysis pointed out specifics form glaucoma. prevailing majority authors note that patients PACG have an average depth anterior chamber....
<p><strong>Introduction:</strong> An increasing microbial resistance to known antibiotics raises the demand for new antimicrobials. New antibacterial agent should have a good activity against planktonic as well biofilm bacteria. Quaternary ammonium compounds (QACs), are widely used in medicine, proven antimicrobial properties, and low toxic irritating. In this study QACs were evaluated their eradication efficiency irrigants combination with Er:YAG...