The oxidative stress biomarker of urinary 8-hydroxy-2′-deoxyguanosine (8-OHdG) was reported to be changed in patients with allergic diseases. Measurement products is noninvasive. However, correlations between the severity levels atopic diseases and remain unclear. This study aimed investigate association among 8-OHdG, dermatitis (AD), phenotypes children. In a nested case-control study, participants kindergarten children were enrolled from Childhood Environment Allergic Diseases Study...

The coronavirus disease (COVID-19) is the global public health challenge currently persisting at a grand scale. A method that meets rapid quantitative detection of antibodies to assess body's immune response from natural COVID-19 illness or vaccines' effects urgently needed. In present study, an attempt was made integrate newly designed spectrometer test strip procedure; this augmentation provides capacity lateral flow immunoassay (LFIA). Optical interpretation results by α index, rather...

To examine the effect of ascent rate on induction acute mountain sickness (AMS) in young adults during a climb to Jiaming Lake (3350 m) Taiwan.Prospective, nonrandomized.Climb from 2370 3350 m.Young (aged 18 26 years) (N = 91) chose participate either fast (3 days; n 43) or slow (4 48) group (1 and 2).Two criteria were used define AMS. A Louise score ≥3 [in setting recent gain altitude, presence headache at least 1 gastrointestinal discomfort (anorexia, nausea, vomiting), fatigue weakness,...

Cerebral Small Vessel Disease (CSVD) frequently affects the elderly, with inflammation playing a crucial role in related health complications, including dementia, stroke, and SVD. Studies, animal experiments, indicate strong link between SVD progression. The Neutrophil-Lymphocyte Ratio (NLR) serves as possible biomarker for ongoing inflammatory risks. A total of 720 adults aged 50 years or older from community-based I-Lan Longitudinal Aging Study were included this study. General linear...

Contrast-enhanced computed tomographic venography (CTV) or magnetic resonance (MRV) are usually used to detect May-Thurner syndrome (MTS). However, both associated with contrast-induced nephrotoxicity. For patients who cannot receive contrast media, non-contrast-enhanced MRV using three-dimensional (3D) turbo spin-echo (TSE) is considered an alternative. We report a case of MTS describe its clinical utility and advantages.A 49-year-old male experienced isolated left leg swelling pain for...

BACKGROUND:The COVID-19 pandemic has spread globally in a short period of time. It is known that antibody (nAb) level can effectively predict vaccine efficacy, which leads to the exploration trials for efficacy assessment. Thus, current study aimed develop platform quantify nAb levels faster, at lower cost, and with better efficiency. MATERIAL AND METHODS:A total 69 sera samples were collected research, 28 from unvaccinated participants. The other 27 remaining 14 participants who had...

The lateral flow immunoassay (LFIA) is a paper-based platform with extensive application in point-of-care (POC) testing and many fields. However, its clinical severely limited due to the lack of quantitative ability standard LFIA tests; this augmentation provides system quantifying signal from magenta-colored AuNPs. To address issue, we proposed an ultra-compact optical that allowed LFIAs be performed more accurately objectively. experimental setup consisted multiple accessories manufactured...

Abstract Background Aortic dissection is a life-threatening syndrome that sometimes requires emergency intervention, and endovascular aortic aneurysm repair (EVAR) treatment option. Long-term image follow-up also required for patients after EVAR due to possible complications. Case presentation We present the case of 73-year-old male with underlying chronic renal disease diagnosed type A who underwent EVAR. Four-dimensional (three spatial dimensions combined time) phase-contrast magnetic...

Although venous duplex ultrasonography (USG) is reliable for diagnosing lower extremity disease (LEVD), cross-sectional imaging studies were usually required before intervention or surgery. Patients of LEVD with renal insufficiency restrict the use contrast-enhanced modalities. In seeking an alternative solution these patients, we explore clinical utility triggered angiography non-contrast-enhanced magnetic resonance (TRANCE-MRI) in assessment LEVD.We collected data from patients presenting...

Lower extremity venous disease (LEVD) is a complex disorder, and determining the etiology of LEVD paramount for treatment selection. Two-dimensional phase-contrast magnetic resonance imaging (2D PC-MRI) can provide an objective measure hemodynamic status may help differentiate between different etiologies LEVD. A total 271 participants, including 256 symptomatic patients with lower 15 healthy volunteers, were collected in this cohort study.It single-center prospective observational study...

This study examines the predictive value of elevated N-terminal-pro brain natriuretic peptide (NT-pro BNP) levels for mortality among patients with end-stage renal disease (ESRD). Data from 768 ESRD patients, excluding those cancer or lost follow-up, were analyzed using Kaplan–Meier curves and Cox proportional hazards models over three years. Results indicated that very high NT-pro BNP had shorter average survival times a significantly higher risk (hazard ratio 1.43). Advanced age, ICU...

The association between short-term changes in serum magnesium level and risk of in-hospital mortality was investigated patients with acute myocardial infarction (AMI). In this retrospective cohort study, data 2,716 AMI were extracted from the Medical Information Mart for Intensive Care (MIMIC-III MIMIC-IV) database 2001-2012. Univariate multivariate Cox proportional hazards models used to explore change AMI. addition, subgroups according age, gender, Sequential Organ Failure Assessment...

Background: Acute myocardial infarction (AMI) is one of a leading cause death. The clinical presentations and outcomes between adults elderly were still not well established. Methods: We conducted prospective study to evaluate the manifestations AMI at emergency department in Taiwan. Patients with unstable angina excluded. primary endpoint was all-cause mortality. inpatient days, discharge activities, complications collected for comparisons. Results: Overall 210 consecutive cases acute...

Background: Indoor air pollution is a constant problem in the current society, especially emergency department (ED). Dirty and polluted hospitals will reduce work efficiency of healthcare staff could ultimately cause diseases illness; some serious acute respiratory are liable to become epidemics hospital. A solution organize medical working environment prevent underlying threat nosocomial infection becoming an increasingly important issue; therefore, research project designed study quality...

A 40‑year‑old male with a history of alcohol and drug addiction presented fever for 1 day in the emergency room. He reported abuse drugs via intravenous injection consumed excessively. Upon arrival to room, his body temperature was 39.4˚C. physical examination, generalized skin gangrene over trunk four limbs were found. Laboratory tests revealed thrombocytopenia (platelets, 67,000/µl) elevated C‑reactive protein (30.4 mg/dl), creatine kinase (>20,000 IU/l), D‑Dimer (>10,000 ng/ml)...

Background: Discrimination of mental illness has formed obstacles to the development public health system. More and more evidence shows that many psychiatric patients say much discrimination in life comes from medical Medical caregivers may also exhibit a discriminatory attitude, resulting decline quality care. Many studies explored whether staff different attitude towards mentally ill general public. However, staff’s working years their social distance are still unclear rare. The...

Video S1 The video that demonstrates the three-dimensional rotating projection of affected extremity showing femoral vein aplasia and extensive venous malformations.

Background: Early detection and isolation of pulmonary tuberculosis (PTB) patients are the key stones in controlling disease. The objective study was to investigate characteristics PTB non-PTB emergent department (ED) room help us early diagnosis recognition suspected ED. Design: Retrospective chart review. Methods: From January 1, 2005, through December 31, 127 adult admitted ED were enrolled under suspicion infection. Medical records including demographic data, results sputum stain...

Abstract: Bezoars are defined as indigestible foreign materials impacting in the gastrointestinal tract, which classified according to what they composed of. Small intestinal obstruction caused by bezoar impaction was a rare disease. However, it has become more and recognized since gastrectomy with truncal vagotomy introduced into treatment of peptic ulcer Computerized tomography (“CT”) is still imaging modality choice preoperative diagnosis small bowel bezoars. Although ultrasound less...

The lateral flow immunoassay (LFIA) is a paper-based platform that has extensive application in point-of-care (POC) testing and many fields. However, its clinical severely limited due to unsatisfactory sensitivity. To address this issue, we proposed an ultra-compact optical system allowed LFIAs be performed more accurately objectively. experimental setup consisted of multiple accessories manufactured by 3D printing (STEP files were included). A high-resolution printer was used print out...

Coronavirus disease (COVID-19) is the current grand global public health challenge. To assess body's immune response from natural COVID-19 or effects of vaccines, it necessary to have a method that meets rapid quantitative detection antibodies. We integrated newly designed spectrochip our test strip procedures provide sensitive, capacity lateral flow immunoassay (LFIA). Optical interpretation results by α index was taken, rather than visual qualification. This can quickly produce in 6...

Video 1 The video demonstrates the 3-dimensional non-contrast magnetic resonance venography of lower limb venous malformation.