First results of endoscopic applications optical coherence tomography for in vivo studies human mucosa respiratory, gastrointestinal, urinary and genital tracts are presented. A novel OCT (EOCT) system has been created that is based on the integration a sampling arm an all-optical-fiber interferometer into standard devices using their biopsy channel to transmit low-coherence radiation investigated tissue. We have studied mucous membranes esophagus, larynx, stomach, bladder, uterine cervix...

We report results of application our endoscopic optical coherence tomography (EOCT) system in clinical experiments to image human internal organs. Based on the experience studying more than 100 patients, we make first general conclusions place and capabilities this method diagnosing mucous membranes. It is demonstrated that EOCT can serve for several purposes such as performing directed biopsy, monitoring functional states body, guiding surgical other treatments post-operative recovery...

Abstract Background and Objective The goal of this study is to apply a new bioimaging modality, the Optical Coherence Tomography (OCT), for intraoperative control in laser surgery laryngeal carcinoma. Study Design/Materials Methods We studied 26 patients with carcinoma situ T 1 , 2 stage. used an endoscopic OCT device imaging at wavelength 0.83 μm acquisition rate approximately 0.5 frames/s single (200 × 200 pixel) tomogram. All were operated surgical YAG:Nd two switchable wavelengths 1.44...

Employment of chlorin-based photosensitizers (PSs) provides additional advantages to photodynamic therapy (PDT) due absorption peak around 405 nm allowing for superficial impact and efficient antimicrobial therapy. We report on the morphological clinical study efficiency PDT at employing PS. Numerical studies demonstrated difference in distribution absorbed dose comparison with traditionally employed wavelength 660 in-depth skin mucous tissues. Morphological was performed inner surface...

Abstract The object of the study was to demonstrate abilities optical coherence tomography (OCT) technique in diagnostics inflammatory processes ear, nose, and throat (ENT). When used nose pharynx, OCT facilitates differential rhinitis enabling differentiation between normal state, two stages allergic rhinitis, vasomotor atrophic pharyngitis. This paper also demonstrates ability monitor changes pharynx induced by cryotherapy. In tympanic cavity differentiate different chronic otitis...

We present a laser resection technique to be used when biotissue is heated by radiation the temperature of material softening and then moved apart lateral edge optical fiber with strongly absorbing tip. The tip allows decrease in power effective cutting scalpel at wavelength 0.97 μm. And it changes speed as well characteristics damage tissues adjacent incision experiments on model media experimental animals.

The usability of time-domain optical coherence tomography equipped with a flexible endoscopic probe for detecting effusion in the tympanic cavity is shown clinical environment. possibility assessing dynamic properties effusion, particularly its contained scatterers' mobility, real cases. A method comparative assessment mobility proposed.

Background . Atopic bronchial asthma (BA) in children is associated with upper airways pathology (UAP). Among them, a combination of allergic rhinitis (AR) and nasal obstructive disorders (NOD), including hypertrophy the pharyngeal tonsil (HPT) anomalies intranasal structures (AINS), abundant. In such patients, anterior active rhinomanometry (AARM) an important method examining patency. However, NOD can influence AARM parameters BA symptoms, this effect must be taken into account clinical...

Acute and chronic infectious inflammatory diseases of the upper respiratory tract occupy one leading places in structure morbidity population world remain most frequent cause patients seeking medical care. The prevalence frequency make a significant contribution to causes temporary disability, which entails negative socio-economic consequences. Specific attention current epidemic season is attracted by change traditional pathogens associated with several strict anti-epidemic measures during...

The aim of the investigation was to assess nasal videoendoscopy capabilities in diagnostics pharyngeal tonsil condition children with atopic bronchial asthma (BA).Materials and Methods.We studied 116 patients aged from 3 17 years (mean age 9.7±4.3years), BA various severity complaining breathing problems, using rigid rhinoscopes (Кarl Storz, Germany), 2.7 4.0 mm diameter, viewing angle being 0 30°, laryngoscope 90° (Atmos, flexible nasopharyngoscope, 3.2 mm, video camera Germany).Control...

The aim of the investigation was to evaluate cutting properties a laser scalpel by applying heavily absorbing coatings (HAC) on an operating silica fiber end.Materials and Methods.In we used with wavelength 0.97 µm output power 3 7 W. Tissue incised without coating coated carbon layer or graphite-based HAC.Results.The assessment ex vivo tissue incision rate showed HAC tip provide maximum rate.Moreover, mode characterized minimum coagulation area.Incision width is slightly less than that...

Bronchial asthma (BA) is often associated with chronic inflammatory processes in the nasal mucosa; these give rise to allergic rhinitis, rhinosinusitis, adenoiditis, and polypous rhinosinusitis.Due their multiple symptoms, diseases of upper respiratory tract, especially are difficult verify patients asthma.The aim study was evaluate diagnostic potential endonasal IR thermometry BA suspected rhinitis.Materials Methods.Fifty children diagnosed both rhinitis 15 healthy children, matched by...

Summary. The aim of the study was to investigate nose and paranasal sinuses pathology in children with atopic bronchial asthma (BA). Nasal cavities were examined 29 BA 10 healthy using nasal videoendoscopy combined ultrasonic scanning maxillary sinusis. Allergic rhinitis (AR) diagnosed all BA. Apart AR, other diseases cavity, pharyngeal lymphatic ring 90 % children. These facts should be considered when treatment rehabilitation programs are being developed.

Chronic nonspecific pharyngitis (CNP) is an extremely common pathology, but there are no consensus documents regulating the diagnosis and treatment of CNP. We compiled a questionnaire with list questions on problem CNF, distributed google form among practitioners conducted survey subsequent analysis answers. Then, search scientific works this topic was carried out platforms PubMed, eLibrary.Ru , CyberLeninka, as well in other open Internet sources. The data specialists compared results...

There is a lack of information about the relationship between age and gender nasal sinonasal symptoms in patients with combined bronchial asthma (BA) allergic rhinosinusitis (ARS) childhood adolescence current bibliographical data. The purpose this research was to study influence factors on children adolescents asthma, rhinitis (AR) and/or ARS. Materials methods used: single-center observational cross-sectional pilot atopic aged 5 17 y/o performed, median 12.0 [9.0; 15.0] years, 73.1%...

Clinical studies using OCT involved 2000 patients in various fields of medicine such as gastroenterology, urology, laryngology, gynecology, dermatology, stomatology, etc. Layered high-contrast images were typical for benign epithelial conditions. distinguish mucosae: epithelium, connective tissue layer, and smooth-muscle layer. Various processes occurring mucosa manifest changes the height, scattering properties course basement membrane. Lack layered structural pattern is main criterion...

The preliminary results of the project devoted to use optical coherence tomography technique evaluate middle ear effusion condition are presented. method estimation viscosity using Fourier analysis OCT data is proposed. provides possibility distinguish areas filled by water and in situ. on especially-developed SD system reported.

The article presents a description and scientific substantiation of cytological aspects confirmation stages otitis media with effusion (OME). pathophysiological mechanisms leading to the formation exudate in middle ear cavity are presented. nature cellular landscape accordance current stage disease is substantiated. Based on study, cytograms were analyzed that reflect specific disease. Each type cytogram allows you reliably assess degree degenerative changes mucous membrane tympanic cavity....

Otitis media with effusion (OME) accounts for 15-17% of the total number recorded diseases middle ear. Surgical methods have become much more common. One factors affecting tactics and effectiveness treatment OME is degree viscosity effusion. Modern diagnostic do not allow to reliably identify cases high viscosity.To study possibilities optical coherence tomography (OCT) in diagnosis a non-invasive viscosity.An analysis results examination 29 patients who underwent surgical - tympanostomy. A...