- Healthcare Decision-Making and Restraints
- Poisoning and overdose treatments
- Handwritten Text Recognition Techniques
- Text and Document Classification Technologies
- Data Quality and Management
- Dementia and Cognitive Impairment Research
- Palliative Care and End-of-Life Issues
- Histone Deacetylase Inhibitors Research
- Topic Modeling
- Potassium and Related Disorders
- Peptidase Inhibition and Analysis
- Chemical Synthesis and Analysis
- Traumatic Ocular and Foreign Body Injuries
- Child Abuse and Related Trauma
- Ethics in medical practice
- Computational Geometry and Mesh Generation
- Geriatric Care and Nursing Homes
- Restraint-Related Deaths
- Family and Patient Care in Intensive Care Units
- Family Caregiving in Mental Illness
- Infectious Encephalopathies and Encephalitis
- Tryptophan and brain disorders
- Skin Diseases and Diabetes
- Whipple's Disease and Interleukins
- Brain Metastases and Treatment
University of Cologne
1924-2023
Fraunhofer Institute for Intelligent Analysis and Information Systems
2016-2022
Deutsche Alzheimer Gesellschaft
2020
German Center for Neurodegenerative Diseases
2018
Sankt-Antonius-Hospital Eschweiler
2014
RWTH Aachen University
2012
Central Institute of Mental Health
2012
Philipps University of Marburg
1996
Robert Koch Institute
1970
Universitäts Frauenklinik
1950
Background: Caregivers providing informal care for people with dementia (PwD) often report unmet needs, burden, and health impairments. Optimal support family caregivers will likely benefit from better understanding assessment of the prevalence types caregivers’ needs associated socio-demographic clinical characteristics. Objective: The present study investigates 1) number 2) characteristics both PwD caregivers, 3) burden health-related outcomes that are related to needs. Methods: analyses...
Abstract Background Although there are a number of support services accessible for most family dementia caregivers, many caregivers reject available and affordable support. Previous research suggests that rejections may result from insufficient fit with caregivers’ unmet needs lack acknowledgement associated services. The present study investigates (a) the number, proportion types rejection on recommended tailored support, (b) socio-demographic clinical determinants caregiver’s both people...
We analyze the mechanism that determines boundary of stability in Taylor–Couette flow. By simple physical argument we derive an analytic expression to approximate line for all radius ratios and speed ratios, co- counterrotating cylinders. The includes viscosity so generalizes Rayleigh’s criterion. achieve agreement with linear theory experiments whole parameter space. Explicit formulae are given limiting cases.
The high number of failed pre-clinical and clinical studies for compounds targeting Alzheimer disease (AD) has demonstrated that there is a need to reassess existing strategies. Here, we pursue holistic, mechanism-centric drug repurposing approach combining computational analytics experimental screening data. Based on this integrative workflow, identified 77 druggable modifiers tau phosphorylation (pTau). One the upstream modulators pTau, HDAC6, was screened with 5,632 drugs in tau-specific...
Abstract Extracting information from documents containing quantitative data in tabular format is an important but still unsolved task due to the heterogeneity of document layouts. This work aims take a step toward developing solution this problem. paper proposes flexible, hybrid table extraction system consisting deep learning-based detection module, heuristic-based structure recognition method, and graph-based semantic interpretation component. The proposed modular supports most frequent...
In this paper, the user requirements, along with methodology adopted towards their identification within i-PROGNOSIS framework (www.i-prognosis.eu), are presented. The latter placed concept of active and healthy ageing (AHA), focusing on case Parkinson's Disease (PD) patients' support. bases for requirements were face-to-face sessions, focus groups a large scale Web-survey. Towards efficient components development, exemplified usage scenarios related business processes stakeholders can...