- Endodontics and Root Canal Treatments
- Dental materials and restorations
- Dental Trauma and Treatments
- Oral microbiology and periodontitis research
- Dental Radiography and Imaging
- Orthopedic Infections and Treatments
- Bone and Joint Diseases
- Osteomyelitis and Bone Disorders Research
- Bone health and treatments
- Oral and Maxillofacial Pathology
- dental development and anomalies
- Trigeminal Neuralgia and Treatments
- Plant-based Medicinal Research
- Ophthalmology and Eye Disorders
- Oral and gingival health research
- Bone Tumor Diagnosis and Treatments
- Infectious Diseases and Tuberculosis
- Neurological Complications and Syndromes
- Facial Nerve Paralysis Treatment and Research
- Dental Research and COVID-19
- 3D Printing in Biomedical Research
- Temporomandibular Joint Disorders
- Pediatric health and respiratory diseases
- Periodontal Regeneration and Treatments
- Sarcoidosis and Beryllium Toxicity Research
Indiana University – Purdue University Indianapolis
2013-2022
American Association of Endodontists
1985-2018
University School
2014-2016
Indiana University
2014-2016
Indianapolis Zoo
2007
Lafayette School Corporation
2004
Merrill (United States)
2004
Morgantown High School
2004
Here we report the synthesis, materials characterization, antimicrobial capacity, and cytocompatibility of novel antibiotic-containing scaffolds. Metronidazole (MET) or Ciprofloxacin/(CIP) was mixed with a polydioxanone (PDS)polymer solution at 5 25 wt% processed into fibers. PDS fibers served as control. Scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), tensile testing, high-performance liquid chromatography (HPLC) were used to assess fiber morphology,...
An electrospun nanocomposite fibrous material holds promise as a scaffold, well drug-delivery device to aid in root maturogenesis and the regeneration of pulp–dentine complex. A novel three-dimensional (3D) scaffold composed polydioxanone (PDS II®) halloysite nanotubes (HNTs) was designed fabricated by electrospinning. Morphology, structure, mechanical properties cell compatibility studies were carried out evaluate effects HNTs incorporation (0.5–10 wt% relative PDS w/w). Overall, 3D porous...
We investigated the effects of triple antibiotic paste (TAP) and modified (MTAP) concentrations on microhardness chemical structure radicular dentine. Human root cylinders were instrumented randomized into four treatment groups an untreated control group. Two received 1 g/mL TAP or MTAP, other two mg/mL methylcellulose-based MTAP. Cylinders stored at 100% relative humidity for 4 weeks. Each cylinder was subjected to a test before after treatment. Different sets dentine specimens treated as...
Abstract Evoked bleeding (EB) clinical procedure, comprising a disinfection step followed by periapical tissue laceration to induce the ingrowth of undifferentiated stem cells from periodontal ligament and alveolar bone, is currently only regenerative‐based therapeutic approach treating pulp necrosis in undeveloped (immature) permanent teeth approved United States. Yet, using antibiotic‐based pastes leads cytotoxic, warranting biocompatible strategy promote root canal with no or minimal...
This study explored the effects of dentine treated with two concentrations double antibiotic paste (DAP) and ethylenediaminetetraacetic acid (EDTA) on attachment proliferation dental pulp stem cells (DPSCs).Radicular samples were prepared identical dimensions randomized into six groups (n = 4). Four at 500 mg ml(-1) or 1 without EDTA. The other EDTA only received no treatment. DPSCs seeded each sample (10 000 per sample). Lactate dehydrogenase activity assays used to calculate attached after...
The aim of this study was to evaluate clinical features that might be related success rates autotransplantation molars with complete root formation.A group 60 patients completely formed third autotransplanted a different molar socket followed for medium period 5 years and months. Extreme care used in order preserve the vitality periodontal ligament cells. same technique applied all teeth despite anatomies. Descriptive statistics performed. association various factors failures assessed by...
We examined 30 male chronic hemodialysis patients and 18 controls without known bone or renal disease to determine the utility of maxillomandibular, non-dominant hand, shoulder pelvis films in evaluation osteodystrophy. used panoramic periapical radiographs examine maxilla mandible sensitive rapid processing for pelvis. Films were evaluated by experienced personnel knowledge patients. There significant differences between creatinine, urea nitrogen, total protein, albumin, alkaline...
We investigated the direct and indirect (residual) antibacterial effects of various concentrations triple antibiotic paste (TAP) loaded into a methylcellulose system. Enterococcus faecalis (E. faecalis) was grown on sterilized dentin blocks (n = 60) treated with clinically used TAP (1,000 mg/mL), low methylcellulose-based (100, 10, 1 placebo paste, or 1.5% NaOCl 10). The pastes were then removed, biofilm disruption assays performed. Additional 120) pretreated same experimental groups 20)....
Previous investigations have identified focal areas of alveolar bone tenderness, increased mucosal temperature, abnormal anesthetic response, radiographic abnormality, radioisotope uptake on scans, and marrow within the quadrant pain in patients with chronic, idiopathic facial pain. The present case reports a 53-year-old man multiple debilitating, "idiopathic" chronic pains, including trigeminal neuralgia atypical neuralgia. At necropsy he was found to numerous separate distinct ischemic...