Marco C. Bottino

ORCID: 0000-0001-8740-2464
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About
Contact & Profiles
Research Areas
  • Dental materials and restorations
  • Endodontics and Root Canal Treatments
  • Bone Tissue Engineering Materials
  • Dental Implant Techniques and Outcomes
  • Electrospun Nanofibers in Biomedical Applications
  • Periodontal Regeneration and Treatments
  • Oral microbiology and periodontitis research
  • 3D Printing in Biomedical Research
  • Dental Erosion and Treatment
  • Dental Trauma and Treatments
  • Dental Anxiety and Anesthesia Techniques
  • Dental Radiography and Imaging
  • Dental Research and COVID-19
  • Orthopaedic implants and arthroplasty
  • Additive Manufacturing and 3D Printing Technologies
  • Tissue Engineering and Regenerative Medicine
  • Graphene and Nanomaterials Applications
  • Wound Healing and Treatments
  • Titanium Alloys Microstructure and Properties
  • Orthopedic Infections and Treatments
  • Bone and Dental Protein Studies
  • Recycling and utilization of industrial and municipal waste in materials production
  • Orthodontics and Dentofacial Orthopedics
  • Material Properties and Applications
  • Advanced ceramic materials synthesis

University of Michigan
2017-2025

Michigan United
2022-2023

John Wiley & Sons (United States)
2016-2022

American Dental Education Association
2022

Faculty of 1000 (United States)
2017-2021

American Association of Endodontists
2020

Ann Arbor Center for Independent Living
2020

Smith College
2016-2020

Syracuse University
2016-2020

University of Rochester
2020

Customization and the production of patient-specific devices, tailoring unique anatomy each patient's jaw facial structures, are new frontiers in dentistry maxillofacial surgery. As a technological advancement, additive manufacturing has been applied to produce customized objects based on 3D computerized models. Therefore, this paper presents advances strategies for devices diverse dental specialties.

10.1016/j.dental.2024.02.006 article EN cc-by Dental Materials 2024-02-24

The quest for finding a suitable scaffold system that supports cell survival and function and, ultimately, the regeneration of pulp–dentin complex remains challenging. Herein, we hypothesized dental pulp stem cells (DPSCs) encapsulated in collagen-based hydrogel with varying stiffness would regenerate functional dentin when concentrically injected into tooth slices. Collagen hydrogels concentrations 3 mg/mL (Col3) 10 (Col10) were prepared, their microstructure assessed using rheometer...

10.1177/00220345241226649 article EN other-oa Journal of Dental Research 2024-02-27

Purpose: The aim of this study was to evaluate the effect two surface conditioning methods on microtensile bond strength a resin cement three high-strength core ceramics: high alumina-based (In-Ceram Alumina, Procera AllCeram) and zirconia-reinforced (in-Ceram Zirconia) ceramics. Materials Methods: Ten blocks (5 x 6 8 mm) In-Ceram Alumina (AL), Zirconia (ZR), (PR) ceramics were fabricated according each manufacturer's instructions duplicated in composite. specimens assigned one following...

10.3290/j.jad.a11226 article EN 2006-06-01

Here we report the synthesis, materials characterization, antimicrobial capacity, and cytocompatibility of novel antibiotic-containing scaffolds. Metronidazole (MET) or Ciprofloxacin/(CIP) was mixed with a polydioxanone (PDS)polymer solution at 5 25 wt% processed into fibers. PDS fibers served as control. Scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), tensile testing, high-performance liquid chromatography (HPLC) were used to assess fiber morphology,...

10.1177/0022034513505770 article EN Journal of Dental Research 2013-09-20

Bioprinting, a promising field in regenerative medicine, holds great potential to create three-dimensional, defect-specific vascularized bones with tremendous opportunities address unmet craniomaxillofacial reconstructive challenges. A cytocompatible bioink is critical prerequisite successfully regenerate functional bone tissue. Synthetic self-assembling peptides have nanofibrous structure resembling the native extracellular matrix (ECM), making them an excellent component. Amorphous...

10.1021/acsami.0c05311 article EN ACS Applied Materials & Interfaces 2020-04-30

A photocrosslinkable gelatin methacryloyl (GelMA) hydrogel has been widely examined in regenerative engineering because of its good cell–tissue affinity and degradability the presence matrix metalloproteinases. halloysite aluminosilicate nanotube (HNT) is a known reservoir for loading sustained delivery therapeutics. Here, we formulate injectable chlorhexidine (CHX)-loaded nanotube-modified GelMA that cytocompatible biodegradable provides release CHX infection ablation while displaying...

10.1021/acsami.9b22964 article EN ACS Applied Materials & Interfaces 2020-03-17

Periodontitis is a chronic inflammatory condition that often causes serious damage to tooth-supporting tissues. The limited successful outcomes of clinically available approaches underscore the need for therapeutics cannot only provide structural guidance cells but can also modulate local immune response. Here, three-dimensional melt electrowritten (

10.1016/j.bioactmat.2022.04.013 article EN cc-by-nc-nd Bioactive Materials 2022-04-22

Major advances in the field of periodontal tissue engineering have favored fabrication biodegradable membranes with tunable physical and biological properties for guided bone regeneration (GBR). Herein, we engineered innovative nanoscale beta-tricalcium phosphate (β-TCP)-laden gelatin methacryloyl/polycaprolactone (GelMA/PCL-TCP) photocrosslinkable composite fibrous via electrospinning. Chemo-morphological findings showed that microfibers had a uniform porous network β-TCP particles...

10.1021/acsami.3c03059 article EN ACS Applied Materials & Interfaces 2023-06-26

An electrospun nanocomposite fibrous material holds promise as a scaffold, well drug-delivery device to aid in root maturogenesis and the regeneration of pulp–dentine complex. A novel three-dimensional (3D) scaffold composed polydioxanone (PDS II®) halloysite nanotubes (HNTs) was designed fabricated by electrospinning. Morphology, structure, mechanical properties cell compatibility studies were carried out evaluate effects HNTs incorporation (0.5–10 wt% relative PDS w/w). Overall, 3D porous...

10.1002/term.1712 article EN Journal of Tissue Engineering and Regenerative Medicine 2013-03-08

10.1016/j.jmbbm.2014.12.009 article EN Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials 2014-12-25
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