A5078916876- Viral-associated cancers and disorders
- Cholesterol and Lipid Metabolism
- Biochemical Analysis and Sensing Techniques
- Virology and Viral Diseases
- Genomics and Phylogenetic Studies
- Cancer-related molecular mechanisms research
- Viral Infectious Diseases and Gene Expression in Insects
- Biofuel production and bioconversion
- Microbial Community Ecology and Physiology
- Identification and Quantification in Food
- Phytochemistry and Bioactive Compounds
- Leptospirosis research and findings
- Peptidase Inhibition and Analysis
- Alkaloids: synthesis and pharmacology
- MicroRNA in disease regulation
- Fatty Acid Research and Health
- RNA and protein synthesis mechanisms
- Food Waste Reduction and Sustainability
- Metabolomics and Mass Spectrometry Studies
- Antioxidant Activity and Oxidative Stress
- Influenza Virus Research Studies
- Circular RNAs in diseases
- Genetic diversity and population structure
- Lymphoma Diagnosis and Treatment
- Wildlife Ecology and Conservation
University of Malaya
2012-2023
Universiti Putra Malaysia
2004
The agricultural sector generates approximately 1300 million tonnes of waste annually, where up to 50% comprising raw material are discarded without treatment. Economic development and rising living standards have increased the quantity complexity generated resulting in environmental, health economic issues. This calls for a greener management system such as valorization or recovery into products. For successful implementation, social acceptance is an essential component with involvement all...
Nasopharyngeal carcinoma (NPC) is originated from the epithelial cells of nasopharynx, Epstein–Barr virus (EBV)‐associated and has highest incidence mortality rates in Southeast Asia. Late presentation a common issue early detection could be key to reduce disease burden. Sensitivity plasma EBV DNA, an established NPC biomarker, for Stage I controversial. Most newly reported biomarkers have neither been externally validated nor compared ones. This causes difficulty planning cost‐effective...
This study determined the potential risk factors that may contribute to seropositivity among dogs and dog handlers from working shelter institutions. Data was collected (n = 266) 161) using a standardised guided questionnaire. Serum obtained tested microscopic agglutination test (MAT). A logistic regression analysis used predict leptospiral of based on factors. total 22.2% 21.7% were seropositive. The significant predictors for dogs' presence rats (OR 4.61 (95% CI: 1.05, 20.33), p 0.043)...
Abstract Arthrobacter alpinus R3.8 is a psychrotolerant bacterial strain isolated from soil sample obtained at Rothera Point, Adelaide Island, close to the Antarctic Peninsula. Strain was sequenced in order help discover potential cold active enzymes with biotechnological applications. Genome analysis identified various adaptation genes including some coding for anti-freeze proteins and cold-shock proteins, involved bioremediation of xenobiotic compounds naphthalene, chitinolytic N...
Two iboga-vobasine bisindoles, 16'-decarbomethoxyvoacamine (1: ) and its 19,20-dihydro derivative, 16'-decarbomethoxydihydrovoacamine (2: from Tabernaemontana corymbosa exhibited potent cytotoxicity against the human colorectal adenocarcinoma HT-29 cells in our previous studies. Bisindoles 1: 2: selectively inhibited growth of without significant to normal colon fibroblasts CCD-18Co. Treatment with bisindoles suppressed formation colonies via G0/G1 cell cycle arrest induction mitochondrial...
Influenza virus is estimated to cause 3-5 million severe complications and about 250-500 thousand deaths per year. Different kinds of anti-influenza drugs have been developed. However, the emergence drug resistant strains has presented a big challenge for efficient antiviral therapy. Indole derivatives shown exhibit both anti-inflammatory activities. In this study, we adopted cell-based system screen potential anti-IAV agents. Four indole (named 525A, 526A, 527A 528A) were subjected...
Rebaudioside A is one of the major diterpene glycosides found in Stevia had been reported to possess anti-hyperlipidemic effects. In this study, we explore potential cholesterol-regulating mechanisms human hepatoma (HepG2) cell line comparison with simvastatin.Cells were incubated at several concentrations (0-10 µM) determine cytotoxicity by MTT assay. Cells treated selected dosage (1 and 5 further experiments. Total cellular lipid was extracted Bligh Dyer method subjected quantitative...
The Malayan pangolin (Manis javanica) is a placental mammal and listed as Critically Endangered on the IUCN Red List of Threatened Species. Most previous attempts to breed pangolins in captivity have met with little success because dietary issues, infections, other complications, although study reported breeding third generation. In our genome sequencing data analysis, we obtained considerable amount bacterial DNA from pregnant female (named "UM3"), which was likely infected by...
Early detection of feline hepatic lipidosis (FHL) with appropriate treatment can increase prognosis significantly. This study looks into the serum biochemistry and lipid composition liver samples in a group stray cats (N=18) collected from pounds Klang Valley, Malaysia. Alanine aminotransferase (ALT) blood was used to detect for damage possibly due FHL, confirmed through light microscopy, (triglyceride, cholesterol, creatinine, urea), triglyceride cholesterol concentrations, RNA expression...