A5032741202- Esophageal and GI Pathology
- Esophageal Cancer Research and Treatment
- MXene and MAX Phase Materials
- Proteoglycans and glycosaminoglycans research
- Carbon Nanotubes in Composites
- Tracheal and airway disorders
- Protease and Inhibitor Mechanisms
- Peptidase Inhibition and Analysis
- Gastroesophageal reflux and treatments
- Polish Historical and Cultural Studies
- Cancer, Hypoxia, and Metabolism
- Advanced Sensor and Energy Harvesting Materials
- Congenital Diaphragmatic Hernia Studies
- Gastric Cancer Management and Outcomes
- Fibroblast Growth Factor Research
- Angiogenesis and VEGF in Cancer
- Ultrasonics and Acoustic Wave Propagation
- Polish socio-economic development
- Pancreatitis Pathology and Treatment
- Education and Cultural Studies
- Geophysical Methods and Applications
- Dysphagia Assessment and Management
- Metastasis and carcinoma case studies
- Glycosylation and Glycoproteins Research
- Urban Development and Cultural Heritage
AGH University of Krakow
2014-2024
Jagiellonian University
2024
Wroclaw Medical University
2010-2023
Weatherford College
2023
Krakow Cardiovascular Research Institute
2020-2021
War Studies Academy
2019
University of Wrocław
2006-2018
University of Łódź
2013
Państwowa Wyższa Szkoła Zawodowa we Włocławku
2012
Niepubliczna Wyższa Szkoła Medyczna
1997
Tumor progression is associated with cell migration, invasion and metastasis. These processes are accompanied by the activation of specific proteases that either linked to cellular membranes or secreted into extracellular spaces. TNF-α known play an important role in various aspects tumor progression. The aim this work was assess effect on migration breast cancer cells and, addition, its association location membrane-associated lipid rafts. Wound scratch healing Transwell assays were used...
Background: Accurate outcome prediction in gastroesophageal malignancies is challenging. Acute-phase response proteins (APRPs) have been claimed to be independent prognosticators, although the basis for their association with prognosis remains unexplained. We hypothesized that, similarly pancreatic and lung cancers, changes APRPs are associated cachexia accelerated angiogenesis.
The aim of the study was investigation relationship between cachexia syndrome and serum resistin, adiponectin, apelin in patients with gastroesophageal cancer (GEC). Adipocytokines concentrations were measured sera 85 GEC 60 healthy controls. They also evaluated tumor tissue appropriate normal mucosa 38 operated patients. Resistin significantly higher than highest resistin levels found cachectic distant metastasis. Serum adiponectin decreased regional Apelin positively correlated hsCRP...
Circulating tumor cells (CTCs) are important targets for treatment and critical surrogate markers when evaluating cancer prognosis therapeutic response. A sensitive methodology detecting CTCs in gastric (GC) patients is needed. In this study we demonstrate a device enrichment cultivation of CTCs. total, 22 with GC, all candidates surgery, were enrolled the study. Peripheral blood samples collected before re-evaluated within operation divided into two groups: resectable non-resectable GC. new...
Background. Stimulation of toll-like receptors (TLRs) has been linked to the development esophageal and gastric cancers.Objectives. The aim study was evaluate clinical significance tissue expression serum concentration TLR-2, TLR-4, TLR-7 TLR-9 in patients with squamous cell carcinoma gastro-esophageal junction adenocarcinoma.Material Methods. group consisted 97 individuals: 32 carcinoma, 27 cancer, 38 ageand gender-matched controls. mRNA protein TLRs tissues sera were measured by reverse...
MXenes are a family of two-dimensional nanomaterials. Titanium carbide MXene (Ti3C2Tx-MXene), reported in 2011, is the first inorganic compound among family. In present work, we report on study composition and various physical properties Ti3C2Tx-MXene nanomaterial, as well their temperature evolution, to consider for space applications. X-ray diffraction, thermal analysis mass spectroscopy measurements confirmed structure terminating groups surface, revealing predominant single OH layer...
Matrix metalloproteinases (MMPs), especially MMP-2 and MMP-9, play an important role in tumor invasion metastasis. This study aimed to determine the serum levels of MMP-2, 130- 225-kDa gelatinolytic bands conventional markers, carcinoembryonic antigen (CEA) cancer (CA) 19-9, patients with gastrointestinal cancers. The relationship between these parameters clinicopathological factors was also studied.Sera from controls (n=19), colorectal (n=47) gastric (n=34) were collected prospectively....
Lymph node metastasis (LNM) is a key factor for selection of treatment method and patients' prognosis in oesophageal squamous cell carcinoma (ESCC). However, no biomarkers able to support the clinical detection LNM have been reported. Recently, vascular endothelial growth C (VEGF-C) was found be more accurate marker lung cancer than computed tomography. Midkine multifunctional cytokine involved development. We investigated circulating midkine levels ESCC patients (n=73) compared with those...
The purpose of this retrospective study is to show that transcervical diverticulectomy (TD) in treatment Zenker diverticulum (ZD) can still be a first choice procedure selected patients and experienced hands its safety might compared the minimally invasive endoscopic diverticulostomy. cohort consisted 44 (18 male, 26 female) operated for (ZD). All underwent open diverticulectomy. decision choose surgical repair depended on risk, age patient, size diverticular septum (the distance between top...
MXenes (Titanium Carbide, Ti3C2-MXene) are two-dimensional nanomaterials that known for their conductivity, film-forming ability, and elasticity. Though literature reports the possibility of usage Ti3C2-MXenes sensor development, material properties response need be studied in detail designing sensors to measure dynamic variables like force, displacement, etc., a environment. due good electro-mechanical can used manufacturing sensing elements engineering biomedical applications. This paper...
The purpose of this study was to evaluate midkine, multipotential cytokine, and growth factor in colorectal cancer (CRC) stratified by tumor location.Midkine assessed immunoenzymatically paired cancerous noncancerous tissues from 53 CRCs referred CRC stage, location, size, circulating cytokine levels.Midkine higher versus tissue 98 % cases (424.2 vs. 31.1 pg/mg, p < 0.0001). Mean fold increase 30.1; 72.5 %, the relative over fivefold. Midkine upregulation more pronounced colon than rectum...
In this work, the deformation behavior of MXene-based polymer composites with bioinspired brick and mortar structures is analyzed. MXene/Polymer nanocomposites are modeled at microscale for configurations nacre-mimetic brick-and-mortar assembly structure. MXenes (brick) matrix (mortar) using classical analytical methods numerical based on finite elements (FE). The provide less accurate estimation elastic properties compared to one. MXene nanocomposite models analyzed FE method estimates...