A5000351611- Lipid Membrane Structure and Behavior
- Synthesis and biological activity
- Erythrocyte Function and Pathophysiology
- Computational Drug Discovery Methods
- Analytical chemistry methods development
- Synthesis and Biological Evaluation
- Advancements in Solid Oxide Fuel Cells
- Arsenic contamination and mitigation
- RNA Interference and Gene Delivery
- Antimicrobial Peptides and Activities
- Public Policy and Governance
- Environmental Toxicology and Ecotoxicology
- Marine Biology and Environmental Chemistry
- Surfactants and Colloidal Systems
- Molecular Sensors and Ion Detection
- Phytochemicals and Antioxidant Activities
- Sphingolipid Metabolism and Signaling
- Aquaculture disease management and microbiota
- Alzheimer's disease research and treatments
- Advanced biosensing and bioanalysis techniques
- Mexican Socioeconomic and Environmental Dynamics
- Protein Interaction Studies and Fluorescence Analysis
- Cholinesterase and Neurodegenerative Diseases
- Social Sciences and Policies
- Bioactive Compounds and Antitumor Agents
Pontificia Universidad Católica de Valparaíso
2015-2024
Universidad Externado de Colombia
2020
University of Concepción
2020
Universidad Independiente
2019
University of Nariño
2017
El Colegio de México
1996-2012
Universidad Católica del Norte
2005-2011
University of Valparaíso
1998-2009
Georgia Institute of Technology
2004-2006
Hospital Quirón Teknon
2002
Changes in the cholesterol (Chol) content of biological membranes are known to alter physicochemical properties lipid lamella and consequently function membrane-associated enzymes. To characterize these changes, we used steady-state time resolved fluorescence spectroscopy two photon-excitation microscopy techniques. The membrane systems were chosen according techniques that used: large unilamellar vesicles (LUVs) for cuvette giant (GUVs) measurements; they prepared from dipalmitoyl...
Monoamine oxidases (MAOs) are attractive targets in drug design. The inhibition of one the isoforms (A or B) is responsible for modulating levels different neurotransmitters central nervous system, as well production reactive oxygen species. Molecules that act selectively on MAO have been studied deeply, and coumarin has described a promising scaffold. In current manuscript we describe comparative study between 3-phenylcoumarin (endo coumarin-resveratrol-inspired hybrid)...
Solid oxide fuel cells (SOFCs) that were capable of running on sour natural gas fabricated and tested. The electrolyte the SOFCs was yttria-stabilized zirconia (YSZ), anode material a strontium-doped lanthanum vanadate with nominal composition (LSV), cathode porous composite (LSM) YSZ. observed peak power density at 950°C when mixture used as ambient air oxidant. Analysis effluent from SOFC indicated that, apart being oxidized electrochemically to sulfur , significant portion transformed...
Ephedra chilensis K Presl, known locally as pingo-pingo, is a Chilean endemic plant used in traditional medicine an anti-inflammatory and other treatments. However, unlike for the species, there have been no reports on antioxidant cytotoxic effects of this plant. The present study aims to explore potential applications E. extract agent against vitro cancer cell lines relationship between activity.Total anthraquinone, flavonoid, phenolic contents, well activity (DPPH, FRAP, TRAP assays)...
This study examined sulfur tolerant materials for solid oxide fuel cells (SOFCs) operating on and containing fuels, focusing the stability electrochemical performance of perovskite-type in a atmosphere under SOFC conditions atm, Preliminary results indicate anodes general form are stable active toward oxidation In particular, an using as anode has shown good at levels 10%, over 5000 times greater than tolerance level contemporary Ni-based systems. The promising due to drastic improvement...
Cholesterol is known to affect the activity of membrane-bound enzymes, including Na+/K+-ATPase. To gain insight into mechanism cholesterol's effect, we have used various hydrophobic fluorescent probes which insert different regions membrane bilayer and report on degree hydration their environment. Specifially, measured generalized polarization Laurdan lifetime DPH derivatives inserted membranes from pig kidneys enriched in Spectral measurements were also carried out these after modification...
We assessed the reactivity of Sb(V) in human blood. was determined using an HPLC-HG-AFS hyphenated system. partially reduced to Sb(III) blood incubation experiments; however, a highly unstable species. The addition 0.1 mol L−1 EDTA prevented oxidation, thus enabling detection reduction Sb(III). transformation whole because may likely generate redox side effects. Our results indicate that glutathione reducing agent this reaction and significantly decreased GSH/GSSG ratio from 0.32±0.09...
Massive mortalities in farmed larvae of the scallop Argopecten purpuratus have been associated with pathogenic Vibrio outbreaks. An energetic trade-off between development-associated demands and immune capacity has observed. Given that highly unsaturated fatty acids (HUFAs) are essential nutrients for larval development, we evaluated effect diets based on microalgae low high HUFAs (LH HH, respectively) condition response larvae. The results showed HH diet increased cellular membrane fluidity...