A5012891688- Gut microbiota and health
- Kidney Stones and Urolithiasis Treatments
- Probiotics and Fermented Foods
- Genomics and Phylogenetic Studies
- Urinary Tract Infections Management
- Enzyme Production and Characterization
- Microbial Metabolism and Applications
- Pediatric Urology and Nephrology Studies
- Microbial Community Ecology and Physiology
- Microbial bioremediation and biosurfactants
- Fermentation and Sensory Analysis
- Porphyrin Metabolism and Disorders
- Clostridium difficile and Clostridium perfringens research
- Microbial Metabolites in Food Biotechnology
- Pelvic floor disorders treatments
- Bladder and Urothelial Cancer Treatments
- Oral microbiology and periodontitis research
- Biochemical and biochemical processes
- Plant pathogens and resistance mechanisms
- Urinary Bladder and Prostate Research
- Pharmacological Effects of Natural Compounds
- Cancer Research and Treatments
- Food composition and properties
- Sexual function and dysfunction studies
- Q Methodology Applications
Cleveland Clinic
2024-2025
Cleveland Clinic Lerner College of Medicine
2022-2025
National Centre for Cell Science
2015-2024
Yenepoya University
2017-2023
ORCID
2020
Sikkim University
2018-2019
Savitribai Phule Pune University
2016
Diabetes in India has distinct genetic, nutritional, developmental and socio-economic aspects; owing to the fact that changes gut microbiota are associated with diabetes, we employed semiconductor-based sequencing characterize of diabetic subjects from this region. We suggest consolidated dysbiosis eubacterial, archaeal eukaryotic components newly diagnosed (New-DMs) long-standing (Known-DMs) compared healthy (NGTs). Increased abundance phylum Firmicutes (p=0.010) Operational Taxonomic Units...
Abstract Hyperoxaluria due to endogenously synthesized and exogenously ingested oxalates is a leading cause of recurrent oxalate stone formations. Even though, humans largely rely on gut microbiota for homeostasis, hyperoxaluria associated features remain unknown. Based 16S rRNA gene amplicons, targeted metagenomic sequencing formyl-CoA transferase ( frc ) qPCR assay, we demonstrate selective enrichment Oxalate Metabolizing Bacterial Species (OMBS) in condition. Interestingly, higher than...
The early growth phase is a critical period for the development of chicken gut microbiome. In this study, spatiotemporal diversity gastrointestinal microbiota, shifts in taxonomic composition, and relative abundances main bacterial taxa were characterized Kadaknath, high-value indigenous Indian breed, using sequencing V3–V4 region 16S rRNA gene. To assess microbiome composition abundance shifts, three chickens per (3, 28, 35 days) sampled, with microbiota analyzed from regions (crop, small...
Abstract Bats are crucial for proper functioning of an ecosystem. They provide various important services to ecosystem and environment. While, bats well-known carrier pathogenic viruses, their possible role as a potential bacteria is under-explored. Here, using culture-based approach, employing multiple bacteriological media, over thousand were cultivated identified from Rousettus leschenaultii (a frugivorous bat species), the majority which family Enterobacteriaceae putative pathogens....
Chowan, dawdim, humao, hamei, khekhrii, and phut are sun-dried starters used for preparation of alcoholic beverages in North East regions India. We attempted to profile the mycobiome community these by high-throughput sequencing (HTS) method. All fungal populations were found be restricted Ascomycota (67-99%), Zygomycota (0.7-29%), Basidiomycota (0.03-7%), Chytridiomycota (0.0003%). 45 core operational taxonomic units (OTUs) which universally present further weighed 41 genera level 22...
Marcha, thiat, dawdim, hamei, humao, khekhrii, chowan and phut are traditionally prepared amylolytic starters use for production of various ethnic alcoholic beverages in North East states India. The surveillance mycobiome associated with from India have been revealed by using phenotypic molecular tools. We identified Wickerhamomyces anomalus, Pichia anomala, Saccharomycopsis fibuligera, terricola, kudriavzevii, Candida glabrata ITS-PCR. diversity yeasts molds all forty samples was also...
In this study, the probiotic potential of B. velezensis FCW2, isolated from naturally fermented coconut water, was investigated by in vitro and genomic characterization. Our findings highlight key features bacterium which includes, antibacterial activity, high adhesive potential, aggregation capacity, production nutrient secondary metabolites. vivo safety assessment revealed no adverse effects on zebrafish. WGS data FCW2 a complete circular genome 4,147,426 nucleotides GC content 45.87%. We...
Decades of research have made clear that host-associated microbiomes touch all facets health. However, effective therapies target the microbiome been elusive given its inherent complexity. Here, we experimentally examined diet-microbe- host interactions through a complex systems framework, centered on dietary oxalate. Using multiple, independent molecular, animal, and in vitro experimental models, found composition influenced multiple oxalate-microbe-host interfaces. Importantly,...
Decades of research have made clear that host-associated microbiomes touch all facets health. However, effective therapies target the microbiome been elusive given its inherent complexity. Here, we experimentally examined diet-microbe- host interactions through a complex systems framework, centered on dietary oxalate. Using multiple, independent molecular, animal, and in vitro experimental models, found composition influenced multiple oxalate-microbe-host interfaces. Importantly,...
Abstract Background The insulin-like growth factor 2 (IGF2) gene, a paternally imprinted gene inactive in oocytes, plays vital role early embryo development. While five IGF2 variants have been described, the specific expressed human spermatozoa compared to granulosa cells (GCs) remain unclear. Objective To characterize quantity and of transcripts spermatozoa. Methods Post-gradient sperm samples were collected from two healthy, fertile men with normal semen parameters, while GCs isolated...
Idli, a naturally fermented Indian food, is prepared from mixture of rice and black gram (lentil). To understand its microbial community during fermentation, detailed analysis the structural functional dynamics idli microbiome was performed by culture-dependent -independent approaches. The bacterial diversity succession were assessed at different times fermentation 16S rRNA amplicon sequencing. Results highlighted that most microbiota belonged to phylum Firmicutes (70%) Proteobacteria (22%)....