A5032890392- Reproductive Health and Technologies
- Childhood Cancer Survivors' Quality of Life
- Air Quality and Health Impacts
- Demographic Trends and Gender Preferences
- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Acute Lymphoblastic Leukemia research
- Family Support in Illness
- Economic and Financial Impacts of Cancer
- Sperm and Testicular Function
- Birth, Development, and Health
- Sexual Differentiation and Disorders
- Air Quality Monitoring and Forecasting
- Cancer survivorship and care
- Male Reproductive Health Studies
- Adolescent and Pediatric Healthcare
- BRCA gene mutations in cancer
- Palliative Care and End-of-Life Issues
- Cervical Cancer and HPV Research
- Head and Neck Cancer Studies
- Vehicle emissions and performance
- Reproductive Health and Contraception
- Climate Change and Health Impacts
- Hormonal and reproductive studies
- Energy and Environment Impacts
University of Utah
2018-2025
Huntsman Cancer Institute
2018-2025
Scientific Systems (United States)
2023
Social and Scientific Systems (United States)
2023
Rocky Mountain University of Health Professions
2019
National Cancer Institute
2019
Division of Cancer Epidemiology and Genetics
2019
University of Washington
2017
Abstract STUDY QUESTION Can we simultaneously assess risk for multiple cancers to identify familial multicancer patterns in families of azoospermic and severely oligozoospermic men? SUMMARY ANSWER Distinct cancer were observed the azoospermia severe oligozoospermia cohorts, suggesting heterogeneity by both type subfertility within type. WHAT IS KNOWN ALREADY Subfertile men their relatives show increased certain including testicular, thyroid, pediatric. DESIGN, SIZE, DURATION A retrospective...
We investigated insurance coverage among adolescents and young adults (AYA) with cancer before during the COVID-19 pandemic. AYAs diagnosed 15-39 years of age were identified using Utah Cancer Registry records linked University electronic health records. Poisson models calculated incidence rate ratios (IRRs) pre-pandemic (11/4/2017-3/5/2020; n = 2,140) pandemic (3/6/2020-7/6/2022; 1,894) periods. Prior to pandemic, gaps higher (pre-pandemic 16.40%, 13.73%; IRR 0.84, 95%CI 0.71-0.98); more...
Nonobstructive azoospermia (NOA) and primary ovarian insufficiency (POI) have common genetics that may also predispose patients to cancer risk. We hypothesized NOA or severe oligozoospermia the risk of male cancers would be higher in families women with POI. Women POI were identified using International Classification Disease codes electronic medical records (1995-2021) from 2 major healthcare systems Utah reviewed for accuracy. Using genealogy information Population Database, (n = 392)...
Air pollution is a carcinogen and causes pulmonary cardiac complications. We examined the association of fine particulate matter (PM2.5) mortality from cancer all among pediatric, adolescent, young adult (AYA) patients with in Utah, state considerable variation PM2.5.We followed 2,444 pediatric (diagnosed ages 0-14) 13,459 AYA 15-39) diagnosed 1986-2015 diagnosis to 5 10 years postdiagnosis, death, or emigration. measured average monthly PM2.5 by ZIP code during follow-up. Separate...
Abstract The study objective was to identify sociodemographic and coronavirus disease 2019 (COVID-19) factors that are associated with COVID-19 vaccine hesitancy among adolescent young adult (AYA) cancer survivors. Eligible participants were 18 years or older diagnosed as an AYA (ages 15-39 years) received services through program. A total of 342 completed a cross-sectional survey. Our primary outcome—COVID-19 hesitancy—was surveyed 5-point Likert scale operationalized binary outcome (agree...
Abstract Male infertility is associated with elevated rates of aneuploidy and DNA breaks in spermatozoa germline precursors. This common condition not well understood poor individual familial somatic health relative to fertile men. To further understand the extent source genome instability, we used error-corrected duplex sequencing test whether impaired spermatogenesis relatively poorer oligozoospermic men are linked single nucleotide de novo mutation frequencies their sperm blood,...
Purpose: To explore the experiences and perspectives of adolescent young adult (AYA) cancer survivors regarding patient–provider relationships their preferences surrounding type healthcare provider for follow-up care. Methods: We recruited AYA who were diagnosed between ages 15 39 using Utah Cancer Registry. Twenty-eight participated in six focus groups held March May 2015 Salt Lake City St. George, Utah. This analysis focuses on how survivors' about may influence transition into,...
Some chemotherapies that treat childhood cancers have pulmonary-toxic properties increase risk for adverse respiratory-health outcomes. PM2.5 causes similar outcomes but its effect among pulmonary compromised cancer survivors is unknown. This case-crossover study identified the PM2.5-associated odds primary-respiratory hospitalizations and emergency department visits in Utah. We compared chemotherapy-treated to a cancer-free sample. calculated 3-day-average by ZIP code county event control...
Childhood cancer survivors are at higher risk of human papillomavirus (HPV)-related second cancers than adolescents without cancer, yet their HPV vaccination uptake is lower. Using a statewide sample, we evaluated whether missed opportunities for concomitant vaccination.
We investigated the viability of particle bound 1-nitropyrene (1-NP) air concentration measurements as a surrogate diesel exhaust (DE) exposure, compared with industry-standard elemental carbon (EC) and total (TC) measurements. Personal exposures are reported for 18 employees at large underground metal mine during four different monitoring campaigns. Full-shift personal exposure sampling was conducted using Mine Safety Health Administration (MSHA) compliant particulate matter (DPM) impactor...
Financial burden is a major concern for survivors of adolescent and young adult (AYA) cancers. We identified if employment disruptions during the COVID-19 pandemic affected AYA survivors' financial burden.
Adolescents and young adults (AYA, age 15-39 years) with cancer may be at elevated risk for late morbidity following their treatment, but few studies have quantified the excess burden of severe disease in this population. Using population-based data from Utah, we examined inpatient hospitalizations among AYA survivors compared siblings general population.Survivors who were ≥2 years diagnosis diagnosed 1994 to 2015 (N = 6,330), 12,924), an age- sex-matched comparison cohort 18,171) identified...
Human papillomavirus (HPV) vaccinations can reduce pediatric, adolescent, and young adult (PAYA) cancer survivors’ susceptibility to HPV-related subsequent cancers. We examined differences in HPV vaccination initiation completion among a Utah-based cohort of PAYA survivors cancer-free population sample. Participants received primary care at 1 2 health systems during study follow-up: 2006-2016. Vaccination records were identified from these systems, statewide records, an all-payer claims...
Abstract Introduction Sex hormone profile evaluation is commonly used in male infertility assessment to identify potential hormonal imbalances and underlying issues that can impact sperm production, quality, or reproductive organ function. Objective To evaluate the likelihood of having a child subfertile infertile men within five years based on their serum levels initial encounter for evaluation/treatment. Methods We identified retrospective cohort from Subfertility, Health, Assisted...