- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Transplantation: Methods and Outcomes
- Cardiac Arrest and Resuscitation
- Fuel Cells and Related Materials
- Nuclear Physics and Applications
- Cardiac pacing and defibrillation studies
- Underwater Vehicles and Communication Systems
- Viral Infections and Immunology Research
- Tissue Engineering and Regenerative Medicine
- Cardiac Valve Diseases and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Renal Transplantation Outcomes and Treatments
- X-ray Spectroscopy and Fluorescence Analysis
- Radiation Detection and Scintillator Technologies
- Heart Failure Treatment and Management
- Congenital Heart Disease Studies
- Organ Transplantation Techniques and Outcomes
- Organ and Tissue Transplantation Research
- Mesenchymal stem cell research
- Maritime Navigation and Safety
- Electron and X-Ray Spectroscopy Techniques
- Crystallography and Radiation Phenomena
- Cardiovascular Function and Risk Factors
- Advanced X-ray Imaging Techniques
Japan Agency for Marine-Earth Science and Technology
2012-2024
Nippon Paper Industries (Japan)
2016-2024
Municipal Hirakata City Hospital
2023
National Institutes for Quantum Science and Technology
2022
Osaka Police Hospital
2011-2022
National Cerebral and Cardiovascular Center
2012-2021
Osaka University
2003-2021
Osaka International University
2017-2021
Japan Proton Accelerator Research Complex
2012-2021
Osaka Prefectural Government
2021
The endoplasmic reticulum (ER) is recognized as an organelle that participates in folding secretory and membrane proteins. ER responds to stress by upregulating chaperones, but prolonged and/or excess leads apoptosis. However, the potential role of pathophysiological hearts remains unclear.Mice were subjected transverse aortic constriction (TAC) or sham operation. Echocardiographic analysis demonstrated mice 1 4 weeks after TAC had cardiac hypertrophy failure, respectively. Cardiac...
Background: In April 2020, the Japanese government declared a state of emergency due to COVID-19 pandemic, and infection control measures, including requests work from home stay-at-home restrictions, were introduced. This study examined changes in smoking behavior during emergency.
Aims The clinical outcome of severe acute myocarditis patients with cardiogenic shock who require circulatory support devices is not well known. We studied the survival and courses fulminant supported by percutaneous extracorporeal membrane oxygenation (ECMO) compared them those non-fulminant myocarditis. Methods results Patients were divided into following two groups. Fourteen required ECMO for defined as having (F group), whereas 13 had an onset symptoms, but did have compromised, (NF...
We report the current status of software development for chopper spectrometers at Materials and Life Science Facility (MLF), Japan Proton Accelerator Research Complex (J-PARC). Our software, named "Utsusemi", has already been utilized in actual users measurements, while we are proceeding with developments more effective use high flux neutrons event-recording methods.
AMATERAS is a new disk-chopper-type spectrometer installed at Materials and Life Science Experimental Facility (MLF) of J-PARC. equipped with an extra chopper for pulse shaping the upstream position, in addition to monochromating chopper, which conventional spectrometers pulsed source have. Owing use these choppers high peak intensity from coupled moderator MLF, design realizes high-intensity high-energy-resolution measurements quasielastic inelastic neutron scattering experiments. The had...
The short-term clinical benefits of bone marrow mononuclear cell transplantation have been shown in patients with critical limb ischemia. purpose this study was to assess the long-term safety and efficacy thromboangiitis obliterans.Eleven limbs (3 rest pain 8 an ischemic ulcer) were treated by transplantation. followed up for events a mean 684+/-549 days (range 103 1466 days). At 4 weeks, improvement observed all 11 limbs, complete relief (36%). Pain scale (visual analog scale) score...
4SEASONS is a Fermi chopper spectrometer in operation at the Materials and Life Science Experimental Facility (MLF) Japan Proton Accelerator Research Complex (J-PARC). expected to facilitate high-efficiency measurements of weak inelastic signals on novel spin lattice dynamics using thermal neutrons. The equipped with coupled moderator sophisticated components such as an elliptical converging neutron guide high-critical-angle supermirrors, long (2.5 m) position-sensitive detectors,...
The energy-resolved neutron imaging system, RADEN, has been installed at the pulsed source in Materials and Life Science Experimental Facility of Japan Proton Accelerator Research Complex. In addition to conventional radiography tomography, world's first beam-line a source, provides three main options for new, quantitative techniques: Bragg-edge visualize spatial distribution crystallographic information, resonance absorption elemental composition temperature polarized magnetic field...
We report on the excellent performance of a newly constructed soft x-ray helical undulator beamline BL25SU SPring-8 for photon energies 500–1800 eV. The full was designed to perform very high resolution spectroscopy solids with using brilliance, highly circularly polarized radiation. grazing incidence monochromator employs varied-line-spacing plane gratings which operate in convergent light from spherical mirror and focuses monochromatic onto exit slit. A resolving power excess 15 000...
The time-of-flight (TOF) type near-backscattering spectrometer (n-BSS), DNA, with Si crystal analyzers was built and started operation in 2012 at the Materials Life Science Experimental Facility (MLF) of Japan Proton Accelerator Research Complex (J-PARC). DNA is first n-BSS pulse shaping chopper installed a spallation pulsed neutron source. It offers currently highest energy-resolution about 2.4 micro eV by operating double-disk 225 Hz whose phase optimized to narrowest slit 10 mm width....
A new pulsed-neutron instrument, named the Energy-Resolved Neutron Imaging System "RADEN", has been constructed at beam line of BL22 in Materials and Life Science Experimental Facility (MLF) J-PARC. The primary purpose this instrument is to perform energy-resolved neutron imaging experiments through effective utilization pulsed nature beam, making world's first dedicated experiments. RADEN was designed cover a broad energy range: from cold neutrons with down 1.05 meV (or wavelength up 8.8 Å)...
Inappropriate activation of neutrophils plays a pathological role in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). The aim this study was to investigate the functions semaphorin 4D (SEMA4D) regulation neutrophil activation, and its involvement AAV pathogenesis.Serum levels soluble SEMA4D were evaluated by ELISA. Blood cell-surface expression membrane flow cytometry. To determine functional interactions between endothelial plexin B2, wild-type SEMA4D-/- mice cultured...