Tingting Zhang

ORCID: 0000-0002-6074-0321
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About
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Research Areas
  • Plant Virus Research Studies
  • Vibrio bacteria research studies
  • Plant and Fungal Interactions Research
  • Aquaculture disease management and microbiota
  • Bacterial biofilms and quorum sensing
  • Plant Disease Management Techniques
  • Bacteriophages and microbial interactions
  • Antibiotic Resistance in Bacteria
  • Plant Disease Resistance and Genetics
  • Microbial infections and disease research
  • Legionella and Acanthamoeba research
  • Microbial Community Ecology and Physiology
  • Marine Sponges and Natural Products
  • Adipose Tissue and Metabolism
  • Natural product bioactivities and synthesis
  • Plant-Microbe Interactions and Immunity
  • Pharmacological Effects of Natural Compounds
  • Mitochondrial Function and Pathology
  • Salmonella and Campylobacter epidemiology
  • Escherichia coli research studies
  • Bacterial Identification and Susceptibility Testing
  • Microbial Natural Products and Biosynthesis
  • Legume Nitrogen Fixing Symbiosis
  • Nematode management and characterization studies
  • Streptococcal Infections and Treatments

Guiyang Medical University
2018-2025

Nantong University
2022-2024

Shanghai Public Health Clinical Center
2021-2024

Affiliated Hospital of Nantong University
2022-2024

Huazhong University of Science and Technology
2024

Zhengzhou University
2023

Liaoning University of Traditional Chinese Medicine
2021

Anhui Normal University
2015

General Hospital of Shenyang Military Region
2015

Jinzhou Medical University
2015

Mature biofilm formation by Vibrio parahaemolyticus requires exopolysaccharide (EPS), type IV pili, and capsular polysaccharide (CPS). Production of each is strictly regulated various control pathways including quorum sensing (QS) bis-(3′–5′)-cyclic di-GMP (c-di-GMP). QsvR, an AraC-type regulator, integrates into the QS regulatory cascade via direct transcription master regulators, AphA OpaR. Deletion qsvR in wild-type or opaR mutant backgrounds altered V. , suggesting that QsvR may...

10.3389/fmicb.2023.1079653 article EN cc-by Frontiers in Microbiology 2023-02-09

Vibrio parahaemolyticus isolates are generally very sensitive to chloramphenicol. However, it is usually necessary transfer a plasmid carrying chloramphenicol resistance gene into V. investigate the function of specific gene, and effects on bacterial physiology have not been investigated. In this work, sublethal dose were investigated by combined utilization various phenotypic assays RNA sequencing (RNA-seq). The results showed that growth rate, biofilm formation capcity, c-di-GMP synthesis,...

10.3389/fmicb.2023.1275441 article EN cc-by Frontiers in Microbiology 2023-09-26

The L-arabinose inducible pBAD vectors are commonly used to turn on and off the expression of specific genes in bacteria. utilization certain carbohydrates can influence bacterial growth, virulence factor production, biofilm formation. Vibrio parahaemolyticus, causative agent seafood-associated gastroenteritis, grow media with as sole carbon source. However, effects V. parahaemolyticus physiology have not been investigated. In this study, we show that growth rate, formation capacity,...

10.1128/jb.00100-23 article EN Journal of Bacteriology 2023-09-01

The increasing demands for crop production have become a great challenge while people also realizing the significance of reductions in synthetic chemical fertilizer use. Plant growth-promoting rhizobacteria (PGPR) are proven biofertilizers yields by promoting plant growth via various direct or indirect mechanisms. Siderophilic bacteria, as an important type PGPR, can secrete siderophores to chelate unusable Fe3+ soil growth. bacteria been shown play vital roles preventing diseases and...

10.3389/fmicb.2022.870413 article EN cc-by Frontiers in Microbiology 2022-05-09

Parasitic and symbiotic plant-fungus relationships have existed for millions of years, phylogenetic analyses certain virus families indicate transmission between plants fungi. A group tobamo-like viruses from various fungi has recently been identified. Tobamo-like are homologous to plant the Tobamovirus genus in Virgaviridae family, but it was unknown whether they form typical particles can replicate exhibit cell-to-cell movement plants. Here, a novel virus, Nigrospora aurantiaca 1 (NaTLV1),...

10.1128/jvi.02102-24 article EN PubMed 2025-03-31

We showed that Vibrio parahaemolyticus was able to naturally and reversibly switch between wrinkly smooth phenotypes disclosed the gene expression profiles related wrinkly-smooth switching, showing significantly differentially expressed genes two colony morphology were involved in various biological behaviors, including virulence factor production, biofilm formation, metabolism, adaptation, colonization.

10.1128/spectrum.02188-22 article EN cc-by Microbiology Spectrum 2022-09-13

Vibrio parahaemolyticus, a Gram-negative, halophilic bacterium, is leading cause of acute gastroenteritis in humans. AphA and OpaR are the master quorum sensing (QS) regulators operating at low cell density (LCD) high (HCD), respectively. QsvR an AraC-type protein that integrates into QS system to control gene expression by directly controlling transcription aphA opaR. However, regulation itself remains unclear date. In this study, we show vpa0607 qsvR transcribed as operon, vpa0607-qsvR....

10.3389/fmicb.2023.1123524 article EN cc-by Frontiers in Microbiology 2023-01-19

In this study, we describe a novel mycovirus isolated from Ustilaginoidea virens, which was designated virens nonsegmented virus 1 (UvNV-1). The sequence analysis revealed that UvNV-1 has two open reading frames (ORFs). ORF1 encodes an unknown protein, is similar to the hypothetical protein BN7_5177 of Wickerhamomyces ciferrii. ORF2 putative RNA-dependent RNA polymerase (RdRp), most closely related Bryopsis mitochondria-associated dsRNA (BDRM) and likely expressed by +1 ribosomal frameshift...

10.1016/j.virol.2014.06.003 article EN cc-by Virology 2014-07-05

Ustilaginoidea virens is the causal agent of a serious disease rice. Here, we report presence five dsRNA bands ranging from about 1.2, 1.5, 1.7, and 1.8 to 5.6 kb in an isolate this fungus China complete sequence largest segment, putatively representing genome novel virus, designated as RNA virus 1 (UvRV1), UvRV1, which has length 5567 bp two consecutive open reading frames (ORFs) with five-nucleotide overlap. Phylogenetic analysis showed that UvRV1 belongs genus Victorivirus family Totiviridae.

10.1007/s00705-013-1615-9 article EN cc-by Archives of Virology 2013-02-05

Vibrio vulnificus is usually transmitted by consumption of raw or undercooked seafood exposure to seawater and can causes gastroenteritis, wound infection, even sepsis. However, atypical unclear sources V. infection have been reported. Here, we report a case presenting as septicemia in 53-year-old man with hepatitis B virus-associated cirrhosis. The source remained the patient reported no contact seawater. Treatment antibiotics was initiated prior confirmation infection. This provides an...

10.1016/j.heliyon.2023.e18905 article EN cc-by-nc-nd Heliyon 2023-08-01

To date, complete genome sequences of 14 double-stranded RNA (dsRNA) phages are available, and studies have shown that the host range dsRNA is limited. The hosts most belong to genus

10.1128/spectrum.01467-24 article EN cc-by Microbiology Spectrum 2024-10-22

Bacteriophages are considered the most abundant entities on earth. However, there merely seven sequenced double-stranded RNA (dsRNA) phages, compared to thousands of DNA (dsDNA) phages. Interestingly, dsRNA viruses quite common in fungi and usually have a lifestyle commensalism or mutualism. Thus, classical protocol using double-layer agar plates characterize phage plaques might be significantly biased isolation phages beyond strictly lytic lifestyles. we applied for isolating fungal...

10.1128/jvi.00399-21 article EN Journal of Virology 2021-06-16

Two new dihydroisocoumarins (1 and 2), together with six known compounds (3–8), were isolated from the fungus Penicillium sp. XR046 collected Xinren coal area of Guizhou province in China. Their structures elucidated on basis spectroscopic analysis. The absolute configurations C-3 1 2 established by comparison their CD data those compounds. Compounds 1–6 showed anti-microbial activities MIC values range 50∼100 μg/mL against Candida albicans, Staphylococcus epidermidis, Bacillus subtilis,...

10.1080/14786419.2019.1655019 article EN Natural Product Research 2019-08-28
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