A5100448319- Dental materials and restorations
- Oral microbiology and periodontitis research
- Dental Implant Techniques and Outcomes
- Microbial Natural Products and Biosynthesis
- Dental Research and COVID-19
- Oral Health Pathology and Treatment
- Marine Sponges and Natural Products
- Dental Health and Care Utilization
- Salivary Gland Disorders and Functions
- Fungal Biology and Applications
- Dental Erosion and Treatment
- Dental Radiography and Imaging
- Endodontics and Root Canal Treatments
- Composting and Vermicomposting Techniques
- Gut microbiota and health
- Mycorrhizal Fungi and Plant Interactions
- Skin Protection and Aging
- Antimicrobial Peptides and Activities
- Additive Manufacturing and 3D Printing Technologies
- Retinoids in leukemia and cellular processes
- Synthetic Organic Chemistry Methods
- Essential Oils and Antimicrobial Activity
- Orthodontics and Dentofacial Orthopedics
- Plant-derived Lignans Synthesis and Bioactivity
- Constructed Wetlands for Wastewater Treatment
The University of Melbourne
2025
Research Center for Eco-Environmental Sciences
2021-2024
University of Chinese Academy of Sciences
2009-2024
China Medical University
2023-2024
University at Buffalo, State University of New York
2014-2024
First Affiliated Hospital of Zhengzhou University
2024
Shanghai Ninth People's Hospital
2024
Hainan University
2024
Chinese Academy of Sciences
2007-2022
Guiyang Medical University
2019-2021
Oral disease patterns change over time and it is important to conduct epidemiological surveillance population surveys regularly monitor the situation. The overall objectives of present survey were: (1) describe oral health status Chinese children adults in 2015-2016 4th National Health Survey; (2) investigate knowledge, attitudes, behaviours among adults; (3) explore association sociodemographic characteristics, behaviours, adults. A national was conducted a representative sample Local...
Abstract Periodontitis is a chronic inflammation caused by bacterial infection and intimately associated with an overactive immune response. Biomaterials are being utilized more frequently in periodontal therapy due to their designability unique drug delivery system. However, local systemic response reactions driven the implantation of biomaterials could result inflammation, tissue damage, fibrosis, which end up failure implantation. Therefore, immunological adjustment through precise design...
Abstract Background Microbial communities inhabiting human mouth are associated with oral health and disease. Previous studies have indicated the general prevalence of adult gingivitis in China to be high. The aim this study was characterize depth microbiota Chinese adults or without gingivitis, by defining microbial phylogenetic diversity community-structure using highly paralleled pyrosequencing. Methods Six non-smoking Chinese, three (age range 21-39 years, 4 females 2 males) were...
Oral rinses containing chemotherapeutic agents, such as cetylpyridinium chloride (CPC), can alleviate plaque-induced gingival infections, but how oral microbiota respond to these treatments in human population remains poorly understood. Via a double-blinded, randomised controlled trial of 91 subjects, the impact CPC-containing on supragingival plaque was investigated experimental gingivitis, where after 21-day period dental prophylaxis achieve healthy gingivae, received either CPC or water...
A gene cluster (pol) essential for the biosynthesis of polyoxin, a nucleoside antibiotic widely used control phytopathogenic fungi, was cloned from Streptomyces cacaoi. 46,066-bp region sequenced, and 20 39 putative open reading frames were defined as necessary polyoxin evidenced by its production in heterologous host, lividans TK24. The role PolO PolA synthesis demonstrated vivo experiments, their functions unambiguously characterized O-carbamoyltransferase UMP-enolpyruvyltransferase,...
Plaque-induced gingivitis can be alleviated by various treatment regimens. To probe the impacts of anti-gingivitis treatments on plaque microflora, here a double blinded, randomized controlled trial 91 adults with moderate was designed two regimens: brush-alone and brush-plus-rinse treatment. In later group, more reduction in both Plaque Index (TMQHI) Gingival (mean MGI) at Day 3, 11 27 evident, dramatic changes were found between baseline other time points for supragingival microbiota...
Abstract Objectives To compare the effectiveness of using a 0.454% stannous fluoride-containing dentifrice twice daily in relieving dentinal hypersensitivity (DH) Chinese population. Materials and methods This was single-centre, randomized, controlled, examiner-blind, three-treatment-arm, parallel-group study participants with clinically diagnosed DH. Subjects who met inclusion criteria (n = 197) were randomly allocated into 3 groups: test group 66)—using daily; positive control 64)—using...
Single molecule, real-time (SMRT) sequencing was used to characterize mitochondrial (mt) genome of Ophiocordycpes sinensis and analyze the mt genome-wide pattern epigenetic DNA modification. The complete O. sinensis, with a size 157,539 bp, is fourth largest Ascomycota sequenced date. It contained 14 conserved protein-coding genes (PCGs), 1 intronic protein rps3, 27 tRNAs 2 rRNA subunits, which are common characteristics known genomes in Hypocreales. A phylogenetic tree inferred from PCGs...
Despite the oral health risks associated with e-cigarette use (i.e., vaping) and importance of cessation, research exploring experiences views practitioners in relation to e-cigarettes delivering cessation counselling is limited. This study investigated practitioners' (i) effects use, (ii) knowledge perceptions e-cigarettes, (iii) confidence providing advice patients. We also explored desired support preferences for training education related e-cigarettes. A cross-sectional online survey was...
To better understand the microbial basis of oral malodor development in humans, we used a cross-sectional and longitudinal study design pyrosequencing approach to track compare tongue microbiota associated with 29 Chinese adults who underwent consecutive three-day evaluation for amount H 2 S excreted orally. Three levels state (healthy, malodor, severe malodor) were defined based on level. Community structure plaques was more sensitive changes than interpersonal variations or differences...
The polyoxin (POL) biosynthetic gene cluster ( pol ) was recently cloned from Streptomyces cacaoi subsp. asoensis . A 3.3 kb DNA fragment carrying an obvious open reading frame polR ), whose deduced product shows sequence similarity to SanG of ansochromogenes and PimR natalensis , revealed within the cluster. Disruption abolished POL production, which could be complemented by integration a single copy into chromosome non-producing mutant. introduction extra in wild-type strain resulted...
polY, a transcriptional regulatory gene in the polyoxin biosynthetic cluster of Streptomyces cacaoi, was analysed, and its deduced product (PolY) showed amino acid sequence homology to AfsR from coelicolor A3(2). PolY contains an OmpR-like DNA binding domain at N-terminal ATPase middle protein. Disruption polY abolished biosynthesis, which could be restored by integration single copy into chromosome disruption mutant. Transcription polR, pathway-specific controlled polY. Electrophoretic...
Abstract Human skin is exposed daily to environmental stressors, which cause acute damage and inflammation. Over time, this leads morphological visual appearance changes associated with premature ageing. Topical vitamin A derivatives such as retinol (ROL), retinyl palmitate (RPalm) propionate (RP) have been used reverse these improve the of skin. This study investigated a stoichiometric comparison retinoids using in vitro ex vivo models. Skin biopsies were treated topically compare...
Streptomyces ansochromogenes SanG is a pathway-specific regulator that mainly controls the transcription of two transcriptional units involved in nikkomycin biosynthesis. consists three major functional domains: an N-terminal antibiotic regulatory protein (SARP) domain, central ATPase and C-terminal half homologous to guanylate cyclases belonging LuxR family. was expressed Escherichia coli as C-terminally His 6 -tagged protein. The purified SanG-His shown be dimer solution by dynamic light...
Abstract Purpose To evaluate the impact of fabrication technique on marginal fit and resistance lithium disilicate crowns. Materials Methods Twelve ivorine molars were prepared to receive The preparations digitally recorded using an intraoral scanner, crowns designed following anatomy unprepared tooth a design software. fabricated 3 techniques: (1) milling from blocks 3‐axis machine (3XM), (2) 5‐axis (5XM), (3) resin‐wax billet machine, followed by heat‐pressing pattern into (5XWP). For...
Purpose: The skin has evolved a system to prevent pathogenic microorganism colonization and infection. This study examined the role of natural moisturizing factors (NMFs) pH on Staphylococcus aureus ( S. ) growth human stratum corneum (SC). Study Population Methods: A survey with 82 female participants was performed. Participants maintained their daily hygiene routine, except for refraining from using leave-on products forearms day test. Skin sampling performed adhesive tapes. An ex vivo...
Abstract Purpose To compare the fracture strength of three‐unit provisional partial fixed dental prostheses (FDPs) fabricated by an indirect‐direct technique from poly(methylmethacrylate) (PMMA) through digital and conventional workflows, FDPs a direct using Bisacryl (BisA) externally reinforced BisA. Materials Methods Forty partially edentulous typodonts with missing mandibular left first molar standard preparations on second premolar were used to fabricate FDPs. Two materials two...