A5000952549- Neuropeptides and Animal Physiology
- Receptor Mechanisms and Signaling
- Neuroscience and Neuropharmacology Research
- Gut microbiota and health
- Technology Use by Older Adults
- Probiotics and Fermented Foods
- Neurotransmitter Receptor Influence on Behavior
- Smart Cities and Technologies
- Innovative Approaches in Technology and Social Development
- Regulation of Appetite and Obesity
- Pain Mechanisms and Treatments
- Infant Nutrition and Health
- Microbial Metabolites in Food Biotechnology
- Polyamine Metabolism and Applications
- Parkinson's Disease Mechanisms and Treatments
- Dental Erosion and Treatment
- Neurological disorders and treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Muscle metabolism and nutrition
- Dental Anxiety and Anesthesia Techniques
- Child Nutrition and Feeding Issues
- Biochemical effects in animals
- Retinal Development and Disorders
- Amino Acid Enzymes and Metabolism
- Ion channel regulation and function
Clasado BioSciences (United Kingdom)
2022
Link Campus University
2015-2020
Interaction Design (United Kingdom)
2020
University of Reading
2016-2019
Istituto Nazionale per l'Assicurazione Contro gli Infortuni sul Lavoro
2017
Higher Institute for Artistic Industries Roma
2015
Sapienza University of Rome
2007-2011
Novartis (Switzerland)
1999
University of Modena and Reggio Emilia
1985-1997
Karolinska Institutet
1984-1989
Different dietary approaches, such as gluten and casein free diets, or the use of probiotics prebiotics have been suggested in autistic spectrum disorders order to reduce gastrointestinal (GI) disturbances. GI symptoms are particular interest this population due prevalence correlation with severity behavioural traits. Nowadays, there is lack strong evidence about effect interventions on these problems, particularly prebiotics. Therefore, we assessed impact exclusion diets a 6-week Bimuno®...
Children with autism spectrum disorders (ASD) often suffer gastrointestinal problems consistent imbalances in the gut microbial population. Treatment antibiotics or pro/prebiotics has been postulated to regulate microbiota and improve symptoms, but there is a lack of evidence for such approaches, especially prebiotics. This study assessed influence prebiotic galactooligosaccharide (B-GOS) on ecology metabolic function using faecal samples from autistic non-autistic children an vitro model...
Article abstract-Cabergoline is a potent D<sub>2</sub> receptor agonist with half-life of 65 hours that may provide continuous dopaminergic stimulation administered once daily. In this study, we randomized de novo Parkinson9s disease (PD) patients to treatment increasing doses cabergoline (0.25 4 mg/d) or levodopa (100 600 up the optimal maximum tolerated dose. Decreases >30% in motor disability (Unified Disease Rating Scale Factor III) versus baseline were considered indicative clinical...
There is substantial demand for gut health products incorporating probiotics and prebiotics. They are being delivered as ingredients in an increasing range of different product formulations. While new delivery matrices assessed their potential impact on cell viability prebiotic degradation, it unknown whether they should be expected to independently alter the clinical effect a given probiotic prebiotic. We provide overview preclinical data examine degree which efficacy may altered by...
The superoxide dismutase (SOD) activities in cerebral cortex of rat during aging are reported. specific activity cytosol SOD (Cu/Zn dismutase) decreases progressively from the 1st to 30th month postnatal life, whereas mitochondrial increases with age. alterations two enzymatic forms may be due separate regulation mechanisms.
Abstract Objectives To compare the effectiveness of using a 0.454% stannous fluoride-containing dentifrice twice daily in relieving dentinal hypersensitivity (DH) Chinese population. Materials and methods This was single-centre, randomized, controlled, examiner-blind, three-treatment-arm, parallel-group study participants with clinically diagnosed DH. Subjects who met inclusion criteria (n = 197) were randomly allocated into 3 groups: test group 66)—using daily; positive control 64)—using...
To evaluate the impact of an anti-sensitivity toothpaste on oral-health-related quality life (OHrQoL) in a real-world (RW) setting. This was decentralised, prospective, 24-week, open-label study participants with self-reported dentine hypersensitivity (DH). A total 655 enrolled used 5% potassium nitrate per label instructions and completed Dentine Hypersensitivity Experience Questionnaire (DHEQ) Numerical Pain Rating Scale (NPRS) monthly for 24 weeks numerical scale satisfaction...
Abstract Prebiotic oligosaccharides have the ability to generate important changes in gut microbiota composition that may confer health benefits host. Reducing impurities prebiotic mixtures could expand their applications food industries and improve selectivity effect on potential beneficial bacteria such as bifidobacteria lactobacilli. This study aimed determine vitro fermentation properties of a 65 % galacto-oligosaccharide (GOS) content Bimuno ® GOS (B-GOS) metabolites. Fermentation B-GOS...
The biological activities of dietary bioactive polysaccharides have been largely explored. Studies on the immunomodulating effects oligosaccharides and shown that they are able to modulate innate immunity. Prebiotics a class poorly digested carbohydrates mainly produced from fibers, which carbohydrate polymers with ten or more monomeric units as defined by Codex Alimentarius Commission in 2009. Considering capacity prebiotics reducing gut inflammation, aim this study was investigate...
The apparently cooperative binding of 8-(5-thioacetamidofluorescein)-cGMP (SAF-cGMP) to cGMP-binding sites the rod outer segments is regulated by Ca2+ in 0.1-1 microM activity range. High reduces, and low increases affinity SAF-cGMP binding. This regulation involves only intrinsic membrane components. It proposed that an allosteric cGMP can contribute photoreceptor potential adaptation.
Background and Purpose The striatum is one of the regions most sensitive to transient forebrain ischemia. After 30-minute ischemia, areas massive neuronal degeneration are clearly detectable a few hours after insult attain their maximal extension 24 insult. However, for cellular neurochemical parameters it not known whether some recovery occurs at later times. We examined certain cell populations in caudate putamen different times Methods Adult male Sprague-Dawley rats were subjected...
Heat stress exacerbates post-exercise hypotension (PEH) and cardiovascular disturbances from elevated body temperature may contribute to exertion-related incapacity. Mast cell degranulation muscle mass are possible modifiers, though these hypotheses lack practical evidence. This study had three aims: (1) characterise pre-post-responses in histamine mast tryptase (MCT), (2) investigate relationships between whole (WBMM) changes blood pressure post-marathon, (3) identify any differences...