A5052647121- Oral microbiology and periodontitis research
- Gut microbiota and health
- Plant and animal studies
- Light effects on plants
- Insect and Arachnid Ecology and Behavior
- Salivary Gland Disorders and Functions
- Oral Health Pathology and Treatment
- Plant Molecular Biology Research
- Traditional Chinese Medicine Analysis
- Plant Gene Expression Analysis
- Insect-Plant Interactions and Control
- Microbial Metabolic Engineering and Bioproduction
- Insect and Pesticide Research
- Metabolomics and Mass Spectrometry Studies
- Chromatography in Natural Products
- Plant Parasitism and Resistance
- Photosynthetic Processes and Mechanisms
- Dental Health and Care Utilization
- Oral and gingival health research
- Viral Infectious Diseases and Gene Expression in Insects
- Advanced Chemical Sensor Technologies
- Genomics and Phylogenetic Studies
- Traditional Chinese Medicine Studies
- Olfactory and Sensory Function Studies
- CRISPR and Genetic Engineering
National Vaccine and Serum Institute
2022
Center for Excellence in Molecular Plant Sciences
2019-2021
Institute of Botany
2019-2021
University of Chinese Academy of Sciences
2019-2021
Chinese Academy of Sciences
2014-2021
Qingdao Institute of Bioenergy and Bioprocess Technology
2013-2016
Although Traditional Chinese Medicine (TCM) preparations have long history with successful applications, the scientific and systematic quality assessment of TCM mainly focuses on chemical constituents is far from comprehensive. There are currently only few primitive studies biological ingredients in preparations. Here, we proposed a method, M-TCM, for based high-throughput sequencing metagenomic analysis. We tested this method Liuwei Dihuang Wan (LDW), whose been well-defined. Our results...
Oral rinses containing chemotherapeutic agents, such as cetylpyridinium chloride (CPC), can alleviate plaque-induced gingival infections, but how oral microbiota respond to these treatments in human population remains poorly understood. Via a double-blinded, randomised controlled trial of 91 subjects, the impact CPC-containing on supragingival plaque was investigated experimental gingivitis, where after 21-day period dental prophylaxis achieve healthy gingivae, received either CPC or water...
Abstract Leaf senescence can be triggered by multiple abiotic stresses including darkness, nutrient limitation, salinity, and drought. Recently, heatwaves have been occurring more frequently, they dramatically affect plant growth development. However, the underlying molecular networks of heat stress-induced leaf remain largely uncharacterized. Here we showed that PHYTOCHROME INTERACTING FACTOR 4 (PIF4) PIF5 proteins could efficiently promote in Arabidopsis. Transcriptomic profiling analysis...
Plaque-induced gingivitis can be alleviated by various treatment regimens. To probe the impacts of anti-gingivitis treatments on plaque microflora, here a double blinded, randomized controlled trial 91 adults with moderate was designed two regimens: brush-alone and brush-plus-rinse treatment. In later group, more reduction in both Plaque Index (TMQHI) Gingival (mean MGI) at Day 3, 11 27 evident, dramatic changes were found between baseline other time points for supragingival microbiota...
To better understand the microbial basis of oral malodor development in humans, we used a cross-sectional and longitudinal study design pyrosequencing approach to track compare tongue microbiota associated with 29 Chinese adults who underwent consecutive three-day evaluation for amount H 2 S excreted orally. Three levels state (healthy, malodor, severe malodor) were defined based on level. Community structure plaques was more sensitive changes than interpersonal variations or differences...
Abstract Termites are considered among the most efficient bioreactors, with high capacities for lignocellulose degradation and utilization. Recently, several studies have characterized gut microbiota of diverse termites. However, temporal dynamics within a given termite dietary diversity poorly understood. Here, we employed 16S rDNA barcoded pyrosequencing analysis to investigate changes in bacterial richness wood‐feeding higher Mironasutitermes shangchengensis under three content‐based...
Abstract Traditional Chinese medicine (TCM) preparations are widely used for healthcare and clinical practice. So far, the methods commonly quality evaluation of TCM mainly focused on chemical ingredients. The biological ingredient analysis is also important because usually contain both plant animal ingredients, which often include some mis-identified herbal materials, adulterants or even contaminants. For analysis, efficiency DNA extraction an factor might affect accuracy reliability...
Molecular bases of eukaryotic circadian clocks mainly rely on transcriptional-translational feedback loops (TTFLs), while epigenetic codes also play critical roles in fine-tuning rhythms. However, unlike histone modification that extensive and well-known the regulation clocks, whether DNA methylation (5mC) can affect clock, associated underlying molecular mechanisms, remains largely unexplored many organisms. Here we demonstrate global genome hypomethylation significantly lengthen period...
Abstract Bioreactors are one of the most important, basic pieces equipment in biopharmaceutical industry. Understanding effects mechanical damage and other factors on physiological state cells during cell matrix culture is basis for continuously achieving greater efficiency higher product quality. In this study, Vero were used as a model apoptosis, senescence, transcriptomics, proteomics, metabolomics carried out analysis at cellular molecular levels. The results showed that compared with...