A5101975938- Autophagy in Disease and Therapy
- CRISPR and Genetic Engineering
- Salmonella and Campylobacter epidemiology
- Genomics and Chromatin Dynamics
- Infant Development and Preterm Care
- Viral gastroenteritis research and epidemiology
- Animal Virus Infections Studies
- Family Dynamics and Relationships
- Bacterial Genetics and Biotechnology
- Sirtuins and Resveratrol in Medicine
- Child and Adolescent Health
- Calcium signaling and nucleotide metabolism
- Intergenerational Family Dynamics and Caregiving
- Neonatal Respiratory Health Research
- Invertebrate Immune Response Mechanisms
- Animal Disease Management and Epidemiology
- Maternal Mental Health During Pregnancy and Postpartum
- Neurobiology and Insect Physiology Research
China University of Geosciences
2024
Shanghai East Hospital
2018
First Hospital of Jilin University
2012-2018
Jilin University
2012-2018
Peking University First Hospital
2017
Peking University
2017
Yangzhou University
2012
Resveratrol, known as phytoalexin, is a natural compound. Clinical studies have revealed that resveratrol has variety of effects including anti‑inflammatory, antivirus and tumor suppressor activities. It been reported it may serve an important role in renal cell carcinoma (RCC) however, the molecular mechanism underlying resveratrol‑induced apoptosis RCC still unclear. The aim present study was to determine whether could suppress progression. Analysis demonstrated act dose‑ time‑dependent...
Histone modifications are critical in regulating neuronal processes. However, the impacts of individual histone on learning and memory elusive. Here, we investigated contributions H3 lysine to Drosophila by using lysine-to-alanine mutants. Behavioural analysis indicated that compared H3WT group, mutants overexpressing H3K23A displayed impaired courtship learning. Chromatin immunoprecipitation showed H3K23 acetylation (H3K23ac) levels were decreased learning-related genes. Knockdown...
Classical swine fever virus (CSFV) can utilize diverse host signaling pathways for its replication; however, the cross talk between mammalian target of rapamycin (mTOR) and CSFV remains unknown. Here, we describe potential role mTOR complex 1 (mTORC1) in promoting replication via virus-induced hypophosphorylation Akt/mTORC1/S6 pathway, especially at an early stage viral infection. Conversely, activation mTORC1 inhibited CSFV. Furthermore, revealed underlying mechanisms pathway mediating...
ABSTRACT Recombinant attenuated Salmonella vaccines have been extensively studied, with a focus on eliciting specific immune responses against foreign antigens. However, very little is known about the innate responses, particularly role of flagellin, in induction immunity triggered by recombinant chickens. In present report, we describe two enterica serovar Typhimurium vaccine strains, wild-type (WT) or flagellin-deficient ( flhD ) , both expressing fusion protein (F) gene Newcastle disease...
1Department of Neonatology, The First Hospital Jilin University, China, 2Department Nursing, China