A5087432546- Cancer Genomics and Diagnostics
- Otitis Media and Relapsing Polychondritis
- Ear Surgery and Otitis Media
- RNA modifications and cancer
- Radiomics and Machine Learning in Medical Imaging
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Epigenetics and DNA Methylation
- Respiratory and Cough-Related Research
- Genomic variations and chromosomal abnormalities
Shaanxi Provincial People's Hospital
2025
Shanxi Medical University
2025
Shanghai Jiao Tong University
2017-2024
Shanghai Ninth People's Hospital
2024
Shanghai Children's Hospital
2023
Shanghai Chest Hospital
2017
The prevention and precise treatment of early-stage lung adenocarcinoma (LUAD) characterized by small nodules (stage IA) remains a significant challenge for clinicians, which is due largely to the limited understanding oncogenic mechanisms spanning from preneoplasia invasive adenocarcinoma. Our study highlights pivotal role cancer cells exhibiting high expression centromere protein F (CENPF), driven TP53 mutations, become increasingly prevalent during transition LUAD. Biologically, (CENPF+)...
Oral leukoplakia (OLK) is a common type of potentially malignant disorder. Early identification the malignancy potential leads to better management OLK and prediction development oral squamous cell carcinoma (OSCC). However, there has been no effective biomarker assess risk in OLK. Genomic copy number alteration (CNA) complex chromosomal structural variation genome identified as multiple cancers. This study aimed develop predictive model for transformation by analysis. A total 431 samples...