A5013311297- Organ Transplantation Techniques and Outcomes
- Cardiac Arrest and Resuscitation
- Organ Donation and Transplantation
- Liver Disease and Transplantation
- Emergency and Acute Care Studies
- Transplantation: Methods and Outcomes
- Central Venous Catheters and Hemodialysis
- Antibiotic Resistance in Bacteria
- Healthcare Systems and Practices
- Renal Transplantation Outcomes and Treatments
- Pleural and Pulmonary Diseases
- Respiratory Support and Mechanisms
- Nosocomial Infections in ICU
- Sepsis Diagnosis and Treatment
- Health, Medicine and Society
- Trauma and Emergency Care Studies
- Antibiotics Pharmacokinetics and Efficacy
- Vibrio bacteria research studies
- Diphtheria, Corynebacterium, and Tetanus
- Cardiac Ischemia and Reperfusion
- Ureteral procedures and complications
- Pneumothorax, Barotrauma, Emphysema
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Dialysis and Renal Disease Management
- Restraint-Related Deaths
Centre Hospitalier Universitaire de Rennes
2018-2021
Centre Hospitalier Universitaire de Poitiers
2007-2020
Université de Poitiers
2013-2016
Inserm
2014-2015
Laboratoire de Génétique Cellulaire
2010
Centre Jean Bernard
2006
Centre Médical de La Teppe
2002
Société de Réanimation de Langue Française
1998
Centre Hospitalier Universitaire d'Angers
1996
Circulatory failure during brain death organ donor resuscitation is a problem that compromises recovery of organs. Combined administration steroid, thyroxine and vasopressin has been proposed to optimize the management deceased donors before However single hydrocortisone not rigorously evaluated in any trial.In this prospective multicenter cluster study, 259 subjects were included. Administration low-dose steroids composed steroid group (n = 102).Although there more patients who received...
Gentamicin is a widely used antibiotic in the intensive care unit (ICU). Its dosage difficult to adapt hemodialyzed ICU patients. The FDA-approved regimen consists of administration 1 1.7 mg/kg gentamicin at end each dialysis session. Better pharmacokinetic management could be obtained if were administered just before We performed Monte Carlo simulations (MCS) determine best profile (high peak and low trough concentrations). Then, 6 was infused into 10 patients over period 30 min. A 4-h-long...
Extracorporeal membranous oxygenation is proposed for abdominal organ procurement from donation after circulatory determination of death (DCD). In France, the national Agency Biomedicine supervises kidneys DCD, specifying durations tolerated warm and cold ischemia. However, no study has determined optimal conditions this technique. The aim work was to develop a preclinical model DCD using normothermic oxygenated recirculation (ANOR). short, our objectives are characterize mechanisms involved...
The current organ shortage in hepatic transplantation leads to increased use of marginal livers. New sources are needed, and deceased after circulatory death (DCD) donors present an interesting possibility. However, many unknown remains on these their pathophysiology regarding ischemia reperfusion injury (IRI). Our hypothesis was that DCD combined with abdominal normothermic regional recirculation (ANOR) is not inferior brain (DBD) donors. We performed a mechanistic comparison between livers...
Le constat qu’une part importante de l’activité réanimation est consacrée à la prise en charge patients ne nécessitant surveillance attentive et nécessité d’une rationalisation du fonctionnement ces unités conduit mise place d’unités intermédiaires entre les soins standards réanimation. Si le concept preuve efficacité structures remonte une vingtaine d’années outre-atlantique, leurs ouvertures France récente, dans cadre des derniers schémas régionaux d’organisation sanitaire. L’organisation...