A5103121890- Neutropenia and Cancer Infections
- Palliative Care and End-of-Life Issues
- Health, Medicine and Society
- Intraperitoneal and Appendiceal Malignancies
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Nosocomial Infections in ICU
- Patient-Provider Communication in Healthcare
- Healthcare Systems and Practices
- Hematological disorders and diagnostics
- Bacterial Identification and Susceptibility Testing
- Ethics in medical practice
- Intensive Care Unit Cognitive Disorders
- Mycobacterium research and diagnosis
- Airway Management and Intubation Techniques
- Family and Patient Care in Intensive Care Units
- Childhood Cancer Survivors' Quality of Life
- Pneumonia and Respiratory Infections
- Chemotherapy-related skin toxicity
- Pneumocystis jirovecii pneumonia detection and treatment
- Central Venous Catheters and Hemodialysis
- Appendicitis Diagnosis and Management
- Health Systems, Economic Evaluations, Quality of Life
- Hematopoietic Stem Cell Transplantation
- Blood disorders and treatments
Renal Association
2024
Institut de la Vision
2023
Institut Gustave Roussy
2013-2023
Université Paris-Saclay
2018-2023
Université Paris Cité
2005-2017
Sorbonne Paris Cité
2017
Maternité Port Royal
2017
Assistance Publique – Hôpitaux de Paris
2001-2017
Hôpital Cochin
2005
Délégation Paris 7
2005
BACKGROUND Peritoneal carcinomatosis (PC) is fatal, despite standard systemic chemotherapy. A new approach that combines maximal surgery with regional chemotherapy has potential to cure selected patients who have colorectal PC. The authors reported the oncologic results of this combined treatment. METHODS performed a retrospective study 64 had PC arising from adenocarcinomas, 19 (29.6%) whom also other metastases. These were treated by complete resection all detectable tumors and 5-day...
Because the overall outcome of critically ill hematologic patients has improved, we evaluated short-term and long-term outcomes poor risk subgroup allogeneic hematopoietic stem-cell transplantation (HSCT) recipients requiring admission to intensive care unit (ICU).This was a retrospective multicenter study HSCT admitted ICU between 1997 2003.Two hundred nine were included in study. Admission occurred during engraftment period (< or = 30 days after transplantation) for 70 139 patients. The...
Ventilator-associated pneumonia (VAP) is difficult to detect and often unsuspected during adult respiratory distress syndrome (ARDS). We prospectively evaluated lower tract (LRT) colonization infection in 30 patients with severe ARDS (PaO2/FIO2 ratio < 150 mm Hg), using repeated quantitative cultures of plugged telescopic catheter (PTC) specimens taken blindly via the endotracheal tube every 48 72 h after onset ARDS. All except one were receiving antibiotics. When VAP was suspected on...
Except for bronchoalveolar lavage, the value of Gram stain examination respiratory tract samples diagnosis hospital-acquired pneumonia (HAP) and their potential impact on empiric antibiotic treatment have rarely been assessed. During a 14-mo period, both plugged telescoping catheter (PTC) endotracheal aspirate (EA) were performed when an HAP was suspected in mechanically ventilated patients. The results examinations cultures previous subsequent prospectively recorded. Two criteria...
To use three severity of illness scores to estimate the probability hospital mortality among patients with cancer and neutropenia; compare performance these scores, calculated at admission an intensive care unit (ICU); test improvement in estimation obtained by taking into account first 72-hr period.Collection data for every neutropenic patient hospitalized ICU during a 4-yr period.A comprehensive center.Ninety-four were admission. Their vital status was measured discharge.The new Simplified...
Although patients with advanced or metastatic lung cancer have poor prognosis, admission to the ICU for management of life-threatening complications has increased over years. Patients newly diagnosed appear as good candidates admission, but more robust information assist decisions is lacking. The aim our study was evaluate prognosis unresectable patients.A retrospective multicentric analyzed outcome admitted a (diagnosis within month) between 2010 and 2013.Out 100 patients, 30 had small cell...
Anxiety results from the anticipation of a threat and might be associated with poor outcome in critically ill. This study aims at showing that anxiety admission ill patients is new organ failure over first 7 days ICU hospitalization independently baseline admission.Prospective multicenter cohort study.Three mixed April 2014 to December 2017.Coma-, delirium-, invasive mechanical ventilation-free admitted were included.None."State anxiety" was assessed using state component State-Trait...
The COVID-19 pandemic has aggressively reached the most vulnerable, not only elderly but also patients with chronic conditions such as cancer. In this study, we present outlines of ethical thinking and measures implemented to try respect our basic values care, in specific environment an oncology hospital.Our ethics committee created watch system based on 24/7 shifts assist practitioners their daily decisions. We discuss challenges faced by cancer during pandemic, access critical care...
Objective To assess the prognostic value of two severity illness scores, commonly used for critically ill patients, Simplified Acute Physiology Score (SAPS II) and Organ Dysfunctions Infection (ODIN), in predicting mortality febrile neutropenic patients hematology wards. Design A 2-month prospective multicenter study. Setting Thirty-six hematologic and/or stem cell transplant units France. Patients All adult with a first episode (polymorphonuclear cells <500/mm3) were included. Interventions...
A novel coronavirus, SARS-CoV-2, was first reported as a respiratory illness in December 2019 Wuhan, China. Since then, the World Health Organization (WHO) Emergency Committee declared global health. COVID-19 has now spread worldwide and is responsible of more than 472,216 persons, out 9,100,090 officially diagnosed since 23 June. In context cancer patients, severe impact, regarding pulmonary infection but also treatments this fragile immunocompromised population, ICU admission for patients...