A5071120659- Protein Interaction Studies and Fluorescence Analysis
- Heavy metals in environment
- Environmental Toxicology and Ecotoxicology
- Mercury impact and mitigation studies
- Quantum Dots Synthesis And Properties
- Toxic Organic Pollutants Impact
- Heavy Metal Exposure and Toxicity
- Nanoparticle-Based Drug Delivery
- Plant Pathogens and Fungal Diseases
- Traditional Chinese Medicine Analysis
- Air Quality and Health Impacts
- Nanoparticles: synthesis and applications
- Chemical Analysis and Environmental Impact
- Environmental and Agricultural Sciences
- Water Treatment and Disinfection
- Trace Elements in Health
- Nanocluster Synthesis and Applications
- Environmental Chemistry and Analysis
- Plant Pathogens and Resistance
- Natural product bioactivities and synthesis
- Supercapacitor Materials and Fabrication
- Effects and risks of endocrine disrupting chemicals
- Language, Metaphor, and Cognition
- Advanced battery technologies research
- Fungal Biology and Applications
Yantai University
2016-2025
Beijing Sanbo Brain Hospital
2024
Capital Medical University
2021-2024
Chinese Academy of Geological Sciences
2024
Ministry of Natural Resources
2021-2024
University of Electronic Science and Technology of China
2021-2024
Institute of Optics and Electronics, Chinese Academy of Sciences
2024
Beijing Normal University
2021-2024
Guizhou Institute of Biology
2024
Land Consolidation and Rehabilitation Center
2024
The tumor stromal microenvironments (TSM) including cells and extracellular matrix (ECM) form an abominable barrier hampering nanoparticles accessibility to cancer cells, significantly compromising their antitumor effects. Herein, we report a bioinspired lipoprotein (bLP) that can induce efficient photothermia remodel TSM improve second bLP for therapy. multiple ECM components in are remarkably disrupted by bLP-mediated photothermal effects, which cause 4.27-fold enhancement of accumulation...
The aim of the present study was to investigate and compare anti‑inflammatory activities curcumin its three metabolites, tetrahydrocurcumin, hexahydrocurcumin octahydrocurcumin in lipopolysaccharide (LPS)‑stimulated RAW 264.7 macrophage cells. results demonstrated that overproduction nitric oxide (NO) potently inhibited following treatment with metabolites. In addition, tetrahydrocurcumin significantly release prominent cytokines, including tumor necrosis factor‑α (TNF‑α) interleukin‑6...
In the present study, in vivo anti-inflammatory activity of Agrimonia pilosa Ledeb (AP) ethanol extract was confirmed experimental animal models, including xylene-induced ear edema mice and carrageenan-induced paw rats. Tiliroside, major component AP extract, isolated purified by high-performance liquid chromatography. The mechanism tiliroside then examined using lipopolysaccharide (LPS)-activated RAW 264.7 macrophage cells. An MTT assay used to determine cytotoxicity a Griess nitric oxide...
The objective of the current study is to evaluate effects dietary supplementation with arginine (ARG), N-carbamylglutamate (NCG), and glutamine (GLN) on rat intestinal morphology antioxidant status under oxidative stress. Rats were fed for 30 d one following iso-nitrogenous diets: basal diet (BD), BD plus 1% ARG, 0.1% NCG, GLN. On day 28, half rats intraperitoneally injected 12 mg/kg body weight diquat (DT; i.e., DT group) other was sterile solution (i.e., control group). groups + GLN [DT...
This study investigated the adverse effects of sodium dodecylbenzenesulfonates (SDBS) on mouse primary hepatocytes by conducting cell viability, intracellular oxidative stress level, and catalase (CAT) activity assays. It was shown that SDBS altered CAT activities, triggered stress, thus exhibited cytotoxicity to hepatocytes. Both stimulation production inhibition molecular contributed change. Molecular mechanisms underlying structural changes were explored isothermal titration calorimetry,...
ABSTRACT Emerging resistance to current antibiotics raises the need for new microbial drug targets. We show that targeting branched-chain amino acid (BCAA) biosynthesis using sulfonylurea herbicides, which inhibit BCAA biosynthetic enzyme acetohydroxyacid synthase (AHAS), can exert bacteriostatic effects on several pathogenic bacteria, including Burkholderia pseudomallei , Pseudomonas aeruginosa and Acinetobacter baumannii . Our results suggest enzymes like AHAS, are lacking in humans, could...