Frédéric Borges

ORCID: 0000-0002-6159-5509
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About
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Research Areas
  • Probiotics and Fermented Foods
  • Genomics and Phylogenetic Studies
  • Streptococcal Infections and Treatments
  • Proteins in Food Systems
  • Neonatal and Maternal Infections
  • Gut microbiota and health
  • Microbial Metabolites in Food Biotechnology
  • Microbial Community Ecology and Physiology
  • Animal Nutrition and Physiology
  • Microbial Inactivation Methods
  • Bacterial Genetics and Biotechnology
  • Enzyme Production and Characterization
  • Microbial Metabolism and Applications
  • Microbial Natural Products and Biosynthesis
  • Identification and Quantification in Food
  • Microbial Metabolic Engineering and Bioproduction
  • Meat and Animal Product Quality
  • Protein Hydrolysis and Bioactive Peptides
  • Biochemical and Structural Characterization
  • Listeria monocytogenes in Food Safety
  • Antimicrobial Peptides and Activities
  • Plant Pathogenic Bacteria Studies
  • Biochemical Analysis and Sensing Techniques
  • Infant Nutrition and Health
  • Antimicrobial Resistance in Staphylococcus

Université de Lorraine
2015-2024

Laboratoire des Biomolécules
2014-2024

Laboratoire d'Ingénierie des Biomolécules
2004-2023

Délégation Centre-Est
2017-2020

Universität Ulm
2006-2011

Laboratoire de Chimie Physique et Microbiologie pour l'Environnement
2003-2009

Laboratoire Sols et Environnement
2009

Dynamique des Génomes et Adaptation Microbienne
2005

Laboratoire de Microbiologie et Génétique Moléculaires
2005

Universidade Federal de Lavras
2003

Streptococcus agalactiae is frequently the cause of bacterial sepsis and meningitis in neonates. In addition, it a commensal bacterium that colonizes mammalian gastrointestinal tract. During its pathogenic lifestyles, S. invades number host compartments, thereby interacting with different proteins. present study, serine-rich repeat protein Srr-1 from was functionally investigated. Immunofluorescence microscopy showed localized on surface streptococcal cells. The shown to interact 62-kDa...

10.1128/iai.00717-07 article EN Infection and Immunity 2007-08-21

Toxic metals (such as lead, cadmium, and, to a lesser extent, aluminum) are detrimental health when ingested in food or water inhaled. By interacting with heavy metals, gut and food-derived microbes can actively and/or passively modulate (by adsorption sequestration) the bioavailability of these toxins inside gut. This “intestinal bioremediation” involves selection safe specifically able immobilize metals. We used inductively coupled plasma mass spectrometry investigate vitro ability 225...

10.3390/microorganisms9020456 article EN cc-by Microorganisms 2021-02-22

Spray drying (SD) is extensively used to encapsulate lactic acid bacteria in large-scale industrial applications; however, combat several harms that reduce their viability. In this study, a novel technique called electrostatic spray (ESD) was explore the benefits and disadvantages of using charge lower temperatures system. Freeze (FD) as reference. The effect different encapsulation agents, like maltodextrin, arabic gum, skim milk, on viability Lacticaseibacillus rhamnosus GG (LGG)...

10.3390/foods12163117 article EN cc-by Foods 2023-08-19

ABSTRACT To better understand the defense mechanism of Streptococcus thermophilus against superoxide stress, molecular analysis 10 menadione-sensitive mutants, obtained by insertional mutagenesis, was undertaken. This allowed identification genes that, with respect to their putative functions, were classified into five categories: (i) those involved in cell wall metabolism, (ii) exopolysaccharide translocation, (iii) RNA modification, (iv) iron homeostasis, and (v) whose functions are still...

10.1128/aem.70.4.2220-2229.2004 article EN cc-by Applied and Environmental Microbiology 2004-04-01

Lactic Acid Bacteria (LAB) differ in their ability to colonize food and animal-associated habitats: while some species are specialized a limited number of habitats, other generalist able multiple animal-linked habitats. In the current study, Carnobacterium was used as model genus elucidate genetic basis these colonization differences. Analyses 16S rRNA gene meta-barcoding data showed that C. maltaromaticum followed by divergens most prevalent foods derived from animals (meat, fish, dairy...

10.3389/fmicb.2017.00357 article EN cc-by Frontiers in Microbiology 2017-03-08

Cell separation is dependent on cell wall hydrolases that cleave the peptidoglycan shared between daughter cells. In Streptococcus thermophilus, this step performed by Cse protein whose depletion resulted in formation of extremely long chains Cse, a natural chimeric enzyme created domain shuffling, carries at least two important domains for its activity: LysM expected to be responsible wall-binding and CHAP predicted contain active centre. Accordingly, localization S. thermophilus surface...

10.1111/j.1365-2958.2009.06595.x article EN Molecular Microbiology 2009-01-23

Abstract We engineered P. putida for the production of isobutanol from glucose by preventing product and precursor degradation, inactivation soluble transhydrogenase SthA, overexpression native ilvC ilvD genes, implementation feedback‐resistant acetolactate synthase AlsS Bacillus subtilis , ketoacid decarboxylase KivD Lactococcus lactis aldehyde dehydrogenase YqhD Escherichia coli . The resulting strain Iso2 produced with a substrate specific yield ( Y Iso/S ) 22 ± 2 mg per gram under...

10.1002/elsc.201900151 article EN cc-by Engineering in Life Sciences 2020-02-18

Abstract Background Microbial communities harbor important biotechnological potential in diverse domains, however, the engineering and propagation of such still face both knowledge know-how gaps. More specifically, culturing tools are needed to propagate shape microbial communities, obtain desired properties, exploit them. Previous work suggested that micro-confinement segregation microorganisms using invert (water-in-oil, w/o) emulsion broth can during propagation, by alleviating biotic...

10.1186/s12934-024-02322-3 article EN cc-by Microbial Cell Factories 2024-02-14

Dairy products are colonized with three main classes of lactic acid bacteria (LAB): opportunistic bacteria, traditional starters, and industrial starters. Most the population structure studies were previously performed LAB species belonging to these give interesting knowledge about at stage where they already industrialized. However, little information prior their use as an starter. Carnobacterium maltaromaticum is a colonizing diverse environments, including dairy products. Since this...

10.1128/aem.00681-14 article EN Applied and Environmental Microbiology 2014-04-19

Complementary microscopy techniques were used to highlight the importance of matrix formulation on lactic acid bacteria delivery system efficiency.

10.1039/c6fo01737a article EN Food & Function 2017-01-01

Within the lactic acid bacterium genus Carnobacterium, Carnobacterium maltaromaticum is one of most frequently isolated species from natural environments and food. It potentially plays a major role in food product biopreservation. We report here on 3.649-Mb chromosome sequence C. LMA 28, which was ripened soft cheese.

10.1128/genomea.00115-12 article EN Genome Announcements 2013-02-01
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