A5101888673- Stress Responses and Cortisol
- Exercise and Physiological Responses
- Thermoregulation and physiological responses
- Dermatology and Skin Diseases
- Neuroendocrine regulation and behavior
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Asthma and respiratory diseases
- Hormonal and reproductive studies
- Early Childhood Education and Development
- Inhalation and Respiratory Drug Delivery
- Tryptophan and brain disorders
- Pediatric Pain Management Techniques
- Surgical Simulation and Training
- Simulation-Based Education in Healthcare
- Adrenal Hormones and Disorders
- Innovations in Medical Education
- Eating Disorders and Behaviors
- Palliative Care and End-of-Life Issues
- Acoustic Wave Phenomena Research
- Child Abuse and Trauma
- Nursing Diagnosis and Documentation
- Vehicle Noise and Vibration Control
- Musculoskeletal pain and rehabilitation
- Infection Control and Ventilation
- Optimism, Hope, and Well-being
Queen's University
2017-2021
Western University
2012-2020
Transnational Press London
2020
University of Winnipeg
2020
Hair cortisol analysis has been shown to be an effective measure of chronic stress. Cortisol is assumed incorporate into hair via serum, sebum, and sweat sources; however, the extent which contributes content unknown.Sweat saliva samples were collected from 17 subjects after a period intensive exercise analyzed by salivary enzyme-linked immunosorbent assay (ELISA). Subsequently, in vitro test on exposure hydrocortisone was conducted. Residual immersed 50-ng/mL solution for periods lasting 15...
The importance of hair cortisol as a long-term retrospective measure systemic exposure is being increasingly recognized, and over recent years, the field analysis has seen rapid expansion with laboratories around globe, integrating into their study designs. These use different methods analysis, presently, no attempt been made to compare them. To move toward clinical utilization this novel method, international benchmark reference values must be established. For that end, 4 leading in testing...
Neonatal pain-related stress is associated with elevated salivary cortisol levels to age 18 months in children born very preterm, compared full-term, suggesting early programming effects. Importantly, interactions between immune/inflammatory and neuroendocrine systems may underlie We examined whether changes persist school age, if common genetic variants the promoter region of NFKBIA gene involved regulation immune inflammatory responses, modify association experience later life as indexed...
A pooled database from diverse community samples was used to examine the associations of hair cortisol concentration (HCC) with self-reported stress and stress-linked mental health measures, including depression, anxiety, alcohol drug use, disability experiences aggression. As part innovative research using a mobile laboratory study health, data were five sub-studies: random sample general population (n = 70), people who had received treatment for and/or substance use problem 78), family...
Hair cortisol concentrations (HCC) are receiving increased attention as a novel biomarker of psychophysiological responses to chronic stress, with potential relevance for psychopathology risk research. We examined the validity HCC marker psychosocial stress in mother (M(age) = 37.87 years)-daughter 7.62 years) dyads characterized by higher (n 30) or lower maternal stress. Additionally, we whether early care moderated similarity levels within dyads. Higher-stress mothers had significantly...
Stress is a well-known predictor of smoking relapse, and cortisol primary biomarker stress. The current pilot study examined changes in levels hair within the context two time-intensity matched behavioral cessation treatments: mindfulness training for smokers cognitive-behavioral comparison group.Eighteen participants were recruited from larger randomized controlled trial cessation.Hair samples (3 cm) obtained 1 month after quit attempt, allowing retrospective analysis at preintervention...
The current study was the first to assess stress reactions associated with wind turbine noise (WTN) exposure using self-reported and objective measures. Randomly selected participants, aged 18–79 yr (606 males; 632 females), living between 0.25 11.22 km from turbines, were exposed outdoor calculated WTN levels up 46 dBA (response rate 78.9%). Multiple regression modeling left great majority (77%–89%) of variance in perceived scale (PSS) scores, hair cortisol concentrations, resting blood...
The analysis of hair cortisol concentrations (HCC) is a promising new biomarker for retrospective measurement chronic stress. effect basic military training (BMT) on stress has not yet been reported. aim this study was to investigate the 10-week BMT HCC, while further exploring role known and novel covariates. Young healthy male recruits Swiss Army participated twice, 10 weeks apart, in data collection (1st examination: n = 177; 2nd 105). On two occasions, we assessed perceived different...
Purpose: Recently, hair cortisol has become a topic of global interest as biomarker chronic stress. Different research groups have been using different methods for extraction and analysis, making it difficult to compare results across studies. A critical examination the reported analytical is important facilitate standardization allow uniform interpretation. Methods: This study qualitatively compared four published procedures from laboratories in Germany, Netherlands, USA Canada. Multiple...
Stress is known to contribute overall health status. Many individuals in sub-Saharan Africa are believed be stressed about their employment, income, and health. This study aimed investigate hair cortisol as a biomarker of chronic stress settlement communities Kenya. Hair samples were collected from 108 volunteers An enzyme-linked immunosorbent assay technique was used measure concentrations. In parallel, survey completed. The mean ± SD for the concentration Naivasha 639 300 ng/g, which...
There is a substantial body of research that utilizes saliva cortisol levels to examine wartime stress; however, there paucity literature hair levels, which allows for long-term assessment chronic stress, investigate the stress war. The present study aimed evaluate changes in concentrations before, during, and after 2011 Libyan war.This examined young adult women who were living Tripoli, Libya during participants recruited at campus Tripoli University. Participants needed have least 24 cm...
The mechanisms underlying the development of persistent posttraumatic pain and disability remain elusive. Recent evidence suggests that disordered stress-system pathway (hypothalamic-pituitary-adrenal axis) activity may be responsible for genesis maintenance long-term sensory emotional problems. However, confidence in current is limited by necessarily retrospective collection data. Hair cortisol can serve as a calendar HPA axis going back several months prior to injury. purposes this pilot...
Healthy individuals tend to consume available rewards like food and sex. This tendency is attenuated or amplified in most stress-related psychiatric conditions, so we asked if it depends on endogenous levels of the 'canonical stress hormone' cortisol. We unobtrusively quantified how hard healthy heterosexual men would work erotic images women versus also measured their exposure cortisol prior two months. used linear models predict strength sexual preference from level, after accounting for...
Simulation is becoming a popular educational modality for physician continuing professional development (CPD). This study sought to characterize how simulation-based CPD (SBCPD) being used in Canada and what academic emergency physicians (AEPs) desire an SBCPD program.Two national surveys were conducted from March June 2018. First, the Needs Assessment Survey was administered online all full-time AEPs across 9 Canadian medicine (EM) sites. Second, Status by telephone department...
Introduction: Some patients with end-stage disease who may neither want nor benefit from aggressive resuscitation receive such treatment if they cannot communicate in an emergency. Timely access to patients' current wishes, or "code status," should be a key metric of electronic health records (EHR). We sought determine what percentage cohort present the emergency department (ED) have accessible, code status documents, and for those do, how quickly can this documentation retrieved.Methods: In...
Hypothalamic-Pituitary-Adrenal (HPA) axis activity is related to negative mental health outcomes, including depression. Most developmental research uses salivary cortisol index HPA activity; however, hair concentrations (HCCs) reflect production over extended periods of time. While HCCs have been linked adult depression, their relationship the development children’s depressive symptoms unclear. We assessed in 60 seven-year-old community-dwelling girls who were followed up one year later. In...