- Financial Risk and Volatility Modeling
- Stochastic processes and financial applications
- Monetary Policy and Economic Impact
- Oral microbiology and periodontitis research
- Gastroesophageal reflux and treatments
- Dental Anxiety and Anesthesia Techniques
- Statistical Methods and Inference
- Dental Health and Care Utilization
- Dental Erosion and Treatment
- Market Dynamics and Volatility
- Dental Implant Techniques and Outcomes
- Acute Kidney Injury Research
- Health Systems, Economic Evaluations, Quality of Life
- Dental Education, Practice, Research
- Probability and Risk Models
- Chronic Kidney Disease and Diabetes
- Blood disorders and treatments
- Insurance, Mortality, Demography, Risk Management
- Orthodontics and Dentofacial Orthopedics
- Platelet Disorders and Treatments
- Blood groups and transfusion
- Dental materials and restorations
- Kidney Stones and Urolithiasis Treatments
CSL (Switzerland)
2019
University of Bern
2014-2017
Institute of Mathematical Statistics
2015
Dental erosion is a complication of gastro-oesophageal reflux disease (GORD) according to the Montreal consensus statement. However, GORD has not been comprehensively characterized in patients with dental erosions and pH-impedance measures have reported.Characterize using 24-h multichannel intraluminal measurements (pH-MII) endoscopy.This single-centre study investigated successive presenting dentists pH-MII endoscopy.Of 374 patients, 298 (80%) reported symptoms <2 per week, 72 (19%) had...
Approximately 60% of patients presenting to dentists with erosive tooth wear have significant gastroesophageal reflux (GERD), despite minor symptoms. No longitudinal studies reflux-associated and characteristics been reported date. The aim this study was characterize the course GERD associated wear, as well factors predictive its progression, in a large group patients.Seventy-two clinically increased esophageal acid exposure by 24-h multichannel intraluminal pH-impedance measurement (MII-pH)...
Objectives To determine whether early acute kidney injury affects mid‐term renal function, to identify risk factors for impaired and highlight the evolution of plasma creatinine estimated glomerular filtration rate in first 12 months after cystectomy urinary diversion. Methods We conducted a single‐center retrospective observational cohort study from 2000 2019. included 900 consecutive patients undergoing Patients with incomplete data preoperative hemodialysis were excluded. Early was...
Isoagglutinins present in intravenous immunoglobulin (IVIG) products have been linked to haemolysis. Therefore, accurately assessing isoagglutinin content IVIG is important. The standard European Pharmacopoeia (Ph.Eur.) direct assay limited by low precision. Here, we describe the development of a fluorescence-activated cell sorting (FACS) method for levels. Serially diluted samples were incubated with red blood cells (RBCs), RBC-bound anti-A and anti-B antibodies detected using...
More than 740 million people worldwide are affected by periodontal disease and at higher risk of secondary damage such as cardiovascular type 2 diabetes, which place a considerable financial burden on healthcare systems. The aim this study was to use computer simulation estimate the direct indirect costs prevention treatment gingivitis, periodontitis related in Swiss population, paid both out pocket (OOP) from social welfare (SW).
 For three different scenarios, iterations with 200,000...
In 1975 James Pickands III showed that the excesses over a high threshold are approximatly Generalized Pareto distributed. Since then, variety of estimators for parameters this cdf have been studied, but always assuming underlying data to be independent. paper we consider special case where arises from linear process with regularly varying (i.e. heavy-tailed) innovations. Using setup, then show likelihood moment introduced by Zhang (2007) consistent distribution.
A variety of estimators for the parameters Generalized Pareto distribution, approximating distribution excesses over a high threshold, have been proposed, always assuming underlying data to be independent. We recently proved that likelihood moment are consistent case where arises from (stationary) linear process with heavy-tailed innovations. In this paper we derive bivariate asymptotic normality under some additional assumptions and give an explicit example on how check these conditions by...