A5071323350- Heavy Metal Exposure and Toxicity
- Trace Elements in Health
- Electromagnetic Fields and Biological Effects
- Human Health and Disease
- Hydrogen's biological and therapeutic effects
- Mercury impact and mitigation studies
- Helicobacter pylori-related gastroenterology studies
- Selenium in Biological Systems
- Bariatric Surgery and Outcomes
- Oral and Maxillofacial Pathology
- Nutrition and Health in Aging
- Bone Tumor Diagnosis and Treatments
- Magnesium in Health and Disease
- Heavy metals in environment
- Bone health and treatments
- Intestinal and Peritoneal Adhesions
- Hepatocellular Carcinoma Treatment and Prognosis
- Workplace Violence and Bullying
- Sodium Intake and Health
- Medical and Biological Ozone Research
- Adipose Tissue and Metabolism
- Biochemical Analysis and Sensing Techniques
- Blood properties and coagulation
- Heart Rate Variability and Autonomic Control
- Gastroesophageal reflux and treatments
Istanbul Aydın University
2018-2024
Istanbul Technical University
2022
Istanbul University-Cerrahpaşa
2020-2022
Istanbul University
2014-2016
Ministry of Health
2013
Hypoxia induces cell death through excessive production of reactive oxygen species (ROS) and calcium (Ca2+) influx in cells TRPM2 cation channel is activated by oxidative stress. Zinc (Zn), selenium (Se), glutathione (GSH) have antioxidant properties several hypoxia-induced activity, ROS may be inhibited the Zn, Se, GSH treatments. We investigated effects on lipid peroxidation (LPO), cytotoxicity inhibition activity transfected HEK293 exposed to hypoxia defined as deficiency.We induced four...
Cigarette smoking deteriorates human health via vascular disorders, cancer and especially respiratory diseases. The aim of this study is to investigate effects cigarette on hemorheologic parameters, plasma osmolality lung function in individuals without diagnosis chronic obstructive pulmonary disease (COPD).Patients diagnosed COPD utilizing test were enrolled the with three groups, ex-smokers (n = 21), current-smokers 35) never-smokers 43). Hemorheologic parameters measured hemorheology...
Background: Methotrexate (MTX) displayed cytotoxic properties against some cancer cells. However, there is very limited data about the possible anti-tumoral potential of them in breast (BC) We aimed to determine effects MTX, which widely used clinical practice, on cell viability, Hypoxia-inducible factor (HIF) -1α, HIF-2α and prolyl 4-hydroxylase-transmembrane (P4H-TM) BC cells (MCF-7) health (HTERT-HME1) treated with MTX. Methods: Human healthy MTX for 24 h, 48h, 72 viability. Results: The...
In the present study, we want to demonstrate correlation between obstructive sleep apnea syndrome (OSAS) whose independent effect on carotid artery intima-media thickness (IMT) was demonstrated, with Framingham risk score (FRS) showing overall cardiovascular risk.IMT of measured ultrasonography and 10-year coronary heart disease (CHD) defined FRS in 90 consecutive patients referred our clinic who underwent polysomnography (PSG), vascular factors without a clinical atherosclerotic disease.IMT...
Background and aims: Ankaferd Blood Stopper (ABS) is a herbal extract obtained from five different plants.It has therapeutic potential for the management of external hemorrhage controlling gastrointestinal bleeding.However, ABS's effects are not unknown on systems.The aim this study was to assess effect short-and long-term systemic exposure safety following oral administration high-dose ABS in rats.Methods: Eighteen healthy adult male rats were included into study.The divided 4 groups: group...
Although there are numerous studies on the health impacts of electromagnetic field (EMF) mobile phone operation frequency 2100 MHz, published works present contradicting results. Long-term exposure to frequencies has unclear hazards. Therefore, it is important investigate molecular mechanism possible biological effects in and determine corresponding markers. Towards this end, study was designed assess effect 200 nM selenium (Se) cell viability% [trypan blue], cycle biomarker [cyclin D1]...
The use of mobile phones is becoming widespread with the development technology, and as a result, its effects on human health are more important every day. Studies have reported that electromagnetic field (EMF) emitted by may adverse biological systems. In order to evaluate effect zinc (Zn) C3H cancer fibroblast cells exposed 2100 MHz EMF, we analyzed cell viability%, nuclear factor kappa b (NF-κB) DNA methyltransferase (DNMT) activities. Cells were divided following groups: Control, sham...
Introduction: Pollution is a deformation of the natural condition earth with physical, chemical, and biological factors. Environmental pollution suppresses life balance has negative effect on living ecosystem its effects food chain. Toxic metal easily enters to chain accumulates in body. Marine species are intensely exposed toxic metals, because habitats feeding habits, metals accumulate their Case: A 56-year-old obese male patient attended Ortakent-Yahsi Family Health Center (Bodrum,...
Son yıllarda yapılan çalışmalar bor bileşiklerinin biyolojik önemi ve insan sağlığı üzerine olası yararlı etkilerini vurgulamaktadır. Bunun yanında yüksek miktarda maruziyetinin olumsuz etkileri olabileceği bildirilmektedir. Borun tümör hücrelerinde anti-kanser anti-proliferatif etkiler gösterebileceği ile ilgili bilgiler bulunmakta, ancak bu etkilerin normal hücreleri nasıl etkileyebileceği henüz tam olarak bilinmemektedir. Çalışmamızda borik asidin (BA) hücre canlılığı/sitotoksisite...
Introduction: Hereditery multiple exostoses (HME) is a rarely autosomal dominant bone tumoral disorder; which characterized by abnormal ossification especially at long bones. The common symptoms are pain, joint movement limitation, malign degeneration, vessel and neuron impression asymmetry of extremities. Material Methods: A 26-year-old male patient (weight 60 kg, height 170 cm) who admitted to Department Orthopedics Out-patient Clinic Cerrahpasa Medical Faculty in July 2013 had been...
This study aimed to determine the correlation between selected electrocardiogram (ECG) parameters (recorded at admission) and mortality in non-cardiac, non-COVID-19 intensive care unit (ICU) patients, sensitivity specificity of a novel admission ECG score (AD-ECG) for predicting mortality. Additionally, AD-ECG Acute Physiology Chronic Health Evaluation II (APACHE II) scores ICU were compared.Clinical laboratory data, compared survivors non-survivors. (the QTc Tpe intervals, Tpe/QT Tpe/QTc...
high charge mobility (200,000 cm 2 V -1 •S ), Young's modulus (~1.0 TPa), thermal conductivity (~5000 Wm •K ) and optical transmittance (~97.7%)have unique thermal, electrical mechanical properties (2-4).Because of these properties, the use graphene-based materials in various biomedical applications, including tissue engineering, biosensing, gene delivery cancer therapy, is increasing day by (1,5).