Paracetamol and piroxicam are non-steroidal anti-inflammatory drugs (NSAIDs), widely used in pain inflammatory diseases.The present study aimed to evaluate the impact of biofield treatment on spectral properties paracetamol piroxicam.The was performed two groups (control treatment) each drug.The control remained as untreated, given groups.Subsequently, both before after were characterized using FT-IR UV-Vis spectroscopic techniques.FT-IR data showed N-H amide II bending peak treated...

Curcumin, a prominent constituent of the rhizome Curcuma longa L., possesses versatile biological properties, which is evidenced from extensive research during last half century. Curcumin has been shown to exhibit antioxidant, anti-inflammatory, antiviral, antibacterial, antifungal, and anticancer activities thus potential against various malignant diseases, such as allergies, arthritis, Alzheimer's disease, other chronic illnesses. In decade it much explored synthetic analogues have...

Raloxifene (RX) in the presence of liver microsomes and glutathione (GSH) has shown oxidative bioactivation to reactive intermediates that are conjugated by GSH. L-Ergothioneine (ET) is a naturally occurring sulfhydryl amino acid, similar GSH, derived from dietary sources with antioxidant properties reported accumulate high concentrations animals humans. We hypothesized ET may have detoxification/conjugation Using rat human mouse, rat, dog, monkey, hepatocytes, novel ergothioneine conjugate...

2-Methyltetrahydrofuran (MTHF) improved separation efficiency, sample loading, and purification, reducing solvent use by 87% process time 89%. It enhanced loading capacity solubility, offering a sustainable, cost-effective solution.

Five new (2, 3, 5, 7, and 9) four known rotenoids (1, 4, 6, 8) were isolated from a methanol extract of Boerhaavia diffusa roots. The structures the elucidated by spectroscopic data interpretation. 70% ethanol extract, rotenoid-rich fraction, all evaluated for their COX-1 COX-2 inhibitory activities. Among tested, compound 7 showed most potent inhibition, with IC50 values 21.7 ± 0.5 25.5 0.6 μM, respectively. Boeravinone B (6) exhibited significant anti-inflammatory activity (56.6% at 50...

The oleo-gum-resin of Boswellia serrata Roxb. (Burseraceae) is widely used for the treatment inflammatory diseases such as osteoarthritis, rheumatoid arthritis and cancer. Anti-inflammatory activity 11-keto-β-boswellic acid (KBA) impeded by poor oral bioavailability due to its high lipid solubility, rapid phase-1 metabolism intestinal permeability.This study developed a poly-dl-lactide-co-glycolide-based nanoparticle formulation KBA improve in vivo anti-inflammatory activity.KBA was isolated...

A series of pyrazolylbenzyltriazoles as celecoxib analogues having a 1,5-diaryl relationship potential leads for the development molecular probes imaging COX-2 expression was prepared by reaction appropriate trifluoromethyl-β-diketones (12a–12i) with 1-[(4-hydrazinophen-1-yl)methyl]-1H-1,2,4-triazole hydrochloride in refluxing ethanol. All compounds were screened vitro cyclooxygenase (COX) assays to determine COX-1 and inhibitory potency. Moreover, anti-inflammatory activity selected...

Boerhavia diffusa L. (Nyctaginaceae) roots are used in Ayurveda for treating inflammatory diseases. Generally poor oral bioavailability is a major problem associated with herbal drugs.To develop phospholipid complex of rotenoid-rich fraction (RRF) and evaluate its vivo anti-inflammatory activity pharmacokinetic study.RRF was prepared from 70% ethanol extract B. roots. This RRF complexed phosphatidylcholine by refluxing ethanol. In RRF-PC determined using the carrageenan-induced rat paw edema...

Abstract Objectives 3-Acetyl-11-keto-β-boswellic acid (AKBA) is a potent anti-inflammatory compound of Boswellia serrata. However, activity AKBA impeded by poor oral bioavailability due to its aqueous solubility. In this context, we aimed develop poly lactic-co-glycolic (PLGA)-based nanoparticle formulation (AKBA-NPs) in order improve and in-vivo rats. Methods AKBA-NPs were prepared characterised analysing particle size zeta potential using sizer, surface morphology scanning electron...

The Murashige and Skoog medium (MS media) is a chemically defined widely used as growth for plant tissue culture techniques. present study was attempted to evaluate the impact of biofield energy treatment on physical, thermal, spectral properties MS media. performed in two groups; one kept control while another subjected Mr. Trivedi’s coded treated group. Afterward, both samples were analyzed using various analytical X-ray diffraction (XRD) analysis showed 19.92% decrease crystallite size...

Boerhaavia diffusa is a perennial herb belonging to Nyctaginaceae. Various classes of chemical constituents such as phenolics (boeravinones), terpenoids and organic acids have been reported in B. roots. As boeravinones proposed putative active for the anti-cancer, spasmolytic anti-inflammatory activities exhibited by extracts, it worthwhile developing validating an ultra-performance liquid chromatography (UPLC) method analysis roots.To develop validate simple, accurate, robust rapid UPLC...

SFRE 199-1 medium (SFRE-M) is important mammalian cell culture medium, used for the of primary cells mammals such as baboon kidney cells. The present study was attempted to evaluate impact biofield energy treatment on physical, thermal and spectral properties SFRE-M. accomplished in two groups; one set control while another subjected Mr. Trivedi’s coded treated group. Subsequently, samples were analyzed using various analytical techniques. CHNO analysis showed about 2.16, 4.87, 5.89%...

Shigella sonnei (S. sonnei) is a non-motile, rod shape, clinically significant, Gram-negative bacterium. It commonly associated with dysentery (shigellosis). Recently, resistance to third and fourth generation cephalosporins fluoroquinolones has been reported in S. sonnei. In the present study, we assessed effect of biofield treatment on phenotyping genotyping characteristic (ATCC 9290). The lyophilized samples were divided three groups (G): G-I (control, revived), G-II (treatment, G-III...

The leaves of Vitex negundo have been reported to contain various bioactive constituents including iridoids and flavonoids. This is the first report on simultaneous determination flavonoids by HPLC in three different samples V. collected from regions India. Separation was accomplished further elaborated for their quantification using a C-18 column with detection at 254 330 nm, respectively. developed method showed good linearity (r2 > or = 0.999), high precision (RSD < 5%) recovery...

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to Rotenoids from Boerhaavia diffusa as Potential Anti-inflammatory AgentsKhemraj Bairwa, Ishwari N. Singh, Somendu K. Roy, Jagdeep Grover, Amit Srivastava, and Sanjay M. Jachak*Cite this: J. Nat. Prod. 2013, 76, 12, 2364Publication Date (Web):November 18, 2013Publication History Published online18 November 2013Published inissue 27 December...

Protose is the enzyme digest of mixed proteins that recommended for culture media, bulk production enzymes, antibiotics, toxins, veterinary preparations, <i>etc.</i> This study was proposed to evaluate effect biofield energy treatment on physicochemical and spectroscopic properties protose. The achieved in two groups <i>i.e.</i> control treated. group remained as untreated, while treated received Mr. Trivedi’s treatment. Finally, both samples were evaluated using various analytical...