A5100459323- Diet, Metabolism, and Disease
- Hip and Femur Fractures
- Liver Disease Diagnosis and Treatment
- Pelvic and Acetabular Injuries
- Cancer-related molecular mechanisms research
- Adipose Tissue and Metabolism
- MicroRNA in disease regulation
- Immune Cell Function and Interaction
- Bladder and Urothelial Cancer Treatments
- Nutritional Studies and Diet
- Insect and Pesticide Research
- Phytoestrogen effects and research
- Cancer, Lipids, and Metabolism
- Ferroptosis and cancer prognosis
- Bone health and treatments
- Lipid metabolism and biosynthesis
- Acute Myeloid Leukemia Research
- Inflammatory Biomarkers in Disease Prognosis
- RNA modifications and cancer
- Cancer Immunotherapy and Biomarkers
- Plant and animal studies
- Cytokine Signaling Pathways and Interactions
- Consumer Market Behavior and Pricing
- Insect-Plant Interactions and Control
- Autoimmune and Inflammatory Disorders Research
Shanghai East Hospital
2021-2025
Chongqing Medical University
2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2025
University of Alberta
2025
Changchun University of Chinese Medicine
2025
China Medical University
2013-2024
Xi'an Jiaotong University
2023-2024
Cotton Research Institute
2019-2024
Zhengzhou University
2024
Endometriosis
2024
Carbapenem-resistant organisms (CRO) have emerged as a significant worldwide issue. However, the availability of efficacious antibiotics for treating CRO infections remains limited. Polymyxins, including colistin sulfate, represent last-line therapeutic option against infections. This study aims to retrospectively evaluate clinical effectiveness and safety sulfate in managing among patients with hematological diseases. Between April 2022 January 2023, total 118 diagnosed infection were...
Background: Beta-blockers are antihypertensive drugs and have shown potential in cancer prognosis. However, this benefit has not been well defined due to inconsistent results from the published studies. Methods: To investigate association between administration of beta-blocker prognosis, we performed a meta-analysis. A literature search PubMed, Embase, Cochrane Library, Web Science was conducted identify all relevant studies up September 1, 2017. Thirty-six involving 319,006 patients were...
Abstract Background Fos-related antigen 2 ( FOSL2 ) plays a facilitative role in fibrotic disease; however, its renal fibrosis remains unclear. This study aimed to clarify the and underlying mechanisms of fibrosis. Methods Upregulated genes unilateral ureteral obstruction (UUO)-injured kidneys were screened Gene Expression Omnibus (GEO) databases, overlapping identified using Venn diagram software. Ontology (GO) Kyoto Encyclopedia Genes Genomes (KEGG) pathway analyses performed for these...
Background: Many studies have evaluated the relationship between alkaline phosphatase (ALP) and prognosis for prostate cancer (PCa). But they not reached a widespread consensus yet. Therefore, we completed meta-analysis to ascertain significance of ALP PCa. Methods: A literature search was performed in PubMed, Embase, Web Science databases. HRs concerning overall survival (OS), progression-free (PFS), cancer-specific (CSS) were extracted evaluate impacts on Subgroup analyses conducted...
Large hemispheric infarction (LHI) is a severe form of stroke with high mortality and poor outcomes. Ultrasonic optic nerve sheath diameter (ONSD) considered an effective indicator for intracranial hypertension. Our study aimed to validate the efficiency ultrasonic ONSD develop nomogram identify LHI patients who have 90-day mortality. We recruited 419 (training cohort, n = 202; internal validation 86; external 131) from six centers. Demographic, laboratory, computed tomography, data were...
Acute Myeloid Leukemia (AML) with KMT2A rearrangements (KMT2Ar), found on chromosome 11q23, is often called KMT2A-rearranged AML (KMT2Ar-AML). This variant highly aggressive, characterized by rapid disease progression and poor outcomes. Growing knowledge of epigenetic changes, especially lactylation, has opened new avenues for investigation management this subtype. Lactylation plays a significant role in cancer, inflammation, tissue regeneration, but the underlying mechanisms are not yet...
This study explores the relationship between 25-hydroxyvitamin D/calcium/alkaline phosphatase (ALP) levels and kidney stone development via cross-sectional Mendelian randomization (MR) analyses. We used data from National Health Nutrition Examination Survey (NHANES) 2013 to 2018 explore associations of 25(OH)D metabolite, calcium, ALP with development, LDSC analysis determine their genetically predicted MR causality those genome-wide association studies (GWASs). The revealed a (Model 1: OR =...
To identify key microRNAs (miRNAs) and their regulatory networks in prostate cancer.Four miRNA three gene expression microarray datasets were downloaded for analysis from Gene Expression Omnibus database. The differentially expressed genes accessed by a GEO2R. Functional pathway enrichment analyses performed using the DAVID program. Protein-protein interaction (PPI) miRNA-mRNA constructed STRING Cytoscape tool. Moreover, results clinical significance validated TCGA data.We identified 26...
Lymph node metastasis (LNM) occurs frequently in young papillary thyroid carcinoma (PTC) patients, though the mortality rates are low. We aimed to analyze relationship between age at diagnosis and LNM PTC a population level elucidate clinical behavior of PTC.Data adult patients with surgically treated follicular (FTC) were identified from Surveillance, Epidemiology, End Results (SEER) database (2004-2015) investigate characteristics by curve estimation. The adjusted odds ratio rate...
Bladder cancer (BC) is a commonly occurring malignant tumor of the urinary system, demonstrating high global morbidity and mortality rates. BC currently lacks widely accepted biomarkers its predictive, preventive, personalized medicine (PPPM) still unsatisfactory. N6-methyladenosine (m6A) modification non-coding RNAs (ncRNAs) have been shown to be effective prognostic immunotherapeutic responsiveness contribute PPPM for various tumors. However, their role in remains unclear. m6A-related...
Abstract Diets high in fat can result obesity and non-alcoholic fatty liver disease (NAFLD). The improvement of NAFLD is an important issue. β -Conglycinin, one the soya proteins, known to prevent hyperlipidaemia, NAFLD. Therefore, we aimed investigate effects -conglycinin on high-fat (HF) diet-induced obese (DIO) mice clarify mechanism underlying these white adipose tissue (WAT). DIO male ddY were divided into six groups: HF, medium-fat (MF) low-fat (LF) groups fed casein, MF LF all which...