Abstract Poly(vinyl alcohol)/poly(acrylic acid) (PVA/PAA) nanofibers with the fiber diameter of 100–150 nanometers were fabricated by electrospinning. PVA/PAA crosslinked heat‐induced esterification and resulting nanofiber mats insoluble in water. α‐Amylase was covalently immobilized onto surfaces via activation amine groups presence 1,1′‐carbonyldiimidazole. The α‐amylase has more resistance to temperature inactivation than that free form showed maximum activity at 50°C. pH‐dependent...

Abstract In this study, polyacrylic acid‐based nanofiber (NF) membrane was prepared via electrospinning method. Acetylcholinesterase (AChE) from Electrophorus electricus covalently immobilized onto NF by demonstrating efficient enzyme immobilization, and immobilization capacity of polymer membranes found to be 0.4 mg/g. The novel synthesized thermally activated surface reconstruction, activation with carbonyldiimidazole upon electrospinning. morphology the investigated scanning electron...

Abstract A new β‐cyclodextrin urethane‐methacrylate monomer was synthesized from the reaction of toluene‐2,4‐diisocyanate, 2‐hydroxyethyl methacrylate (HEMA), and (β‐CD). Based on inclusion character β‐CD, a series hydrogels were prepared by irradiating mixtures (β‐CD‐UM), poly(ethylene glycol) diacrylate (PEG‐DA), HEMA, photoinitator. Gel percentages equilibrium swelling ratios (%) investigated. It observed that equilibrium‐swelling ratio increased with increasing β‐CD‐UM content in...

Abstract Chemically synthesized polyaniline (PANI) was used as polymeric support for xylanase immobilization. The polymer first activated with glutaraldehyde and then successfully immobilized. Xylanase bound characterized using FTIR. optimum pH of the immobilized enzyme at 5, which shifted 1.0 unit to acidic region when compared free enzyme. Thermal stability improved characteristic properties native enzyme, such kinetic activity, reusability storage were also studied temperature....

A high rate (48.6%) of extended spectrum beta-lactamase production among Klebsiella pneumoniae (ESBL-KP) clinical isolates in the paediatric wards our hospital prompted introduction enhanced infection control measures, and after implementation these we instituted a prospective surveillance programme, with nested case-control study to determine risk factors for rectal colonisation by ESBL-KP.Over 1-year period, swabs from patients samples environment hands health-care workers were cultured....

Familial Mediterranean fever (FMF) has episodic or subclinical inflammation that may lead to a decrease in bone mineral density (BMD). The aim of this study was evaluate the effect FMF on metabolism and investigate factors can influence metabolism, such as body mass index (BMI), mutations (MEFV) gene, osteoprotegerin (OPG), leptin inflammatory cytokines, including interleukin (IL)-1β, IL-6 tumor necrosis factor-alpha (TNF-α). OPG, soluble protein produced by osteoblasts, favors increased...

Abstract In this study, α‐amylase was immobilized on glutaraldehyde activated silanized calcium carbonate nanoparticles by a using covalent binding method. The surface modified nano (CaCO 3 ) were characterized FTIR and SEM. Immobilization yield found as 199.43 mg/g of nanoparticles. maximum activity observed at pH 6.5. enzyme had higher elevated temperature (50–90°C) than the free one. Reuse studies demonstrated that could reuse 25 times while retaining 18.2% its activity. Free lost...

Abstract Cardiovascular diseases are one of the primary causes deaths worldwide, and development atherosclerosis is closely related to hypercholesterolemia. As reduction low‐density lipoprotein cholesterol level critical for treating these diseases, inhibition 3‐hydroxy‐3‐methyl‐glutaryl coenzyme A (HMG‐CoA) reductase, which essentially responsible biosynthesis, stands out as a key solution lower plasma levels. In this study, we synthesized several dihydroxycoumarins investigated their...

Oxidative stress possibly helps promote the progression and complications of chronic renal failure (CRF). Haemodialysis (HD) may aggravate oxidative stress. This controlled, cross-sectional clinical study with blind outcome assessment evaluated effect prolonged HD treatment on stress.Seventy patients (M/F = 33/37) CRF who were divided into six groups differing periods HD; from 3 to 12 months 85-120 months. Twelve healthy subjects acted as controls. The serum levels thiobarbituric acid...

α‐amylase was covalently immobilized on functionalized polyimide (PI) membranes via glutaraldehyde (GA) activation. 3,3′,4,4′‐Benzophenonetetracarboxylic acid dianhydride (BTDA) and 4,4′‐oxydianline (4,4′‐ODA) based were obtained thermal imidization. Free amine groups the surface of generated by amination reaction polyimides with hexamethylenediamine (HMDA). Surface‐aminated subjected to enzyme immobilization after GA Immobilization efficiency activity examined at various pH (3.0–8.0)...

This study presents 37 new antioxidant coumarin derivatives and strategies for structural modification to improve their activities, the main ferric-reducing power (FRAP) assay used evaluate properties generation of validated quantitative structure–activity (antioxidant activity) relationship (QSAR) models. In an attempt generate QSAR models, structures all in data set were fully optimized by semi-empirical PM6 method using SPARTAN 10 software. Descriptors calculated DRAGON 6.0 Multiple...

Abstract Diabetes insipidus in pregnancy has different causes. The association of diabetes with disturbances liver function been reported, however, rarely reported HELLP syndrome. We present a 23‐year‐old primigravida singleton gestation complicated by syndrome who developed postpartum insipidus. Labor was induced promptly to terminate because intrauterine fetal death and dysfunction. 1‐deamino‐8‐D‐arginine‐vasopressin administered. dysfunction resolved within 2 weeks. Development may result...

Hypertension is a serious and common health problem experienced by people from all parts of the world. The authors' aim was to assess hypertensive patients' baseline behaviors, status, knowledge about their disease, lifestyles, behaviorial modifications, sources information management hypertension. authors administered 72 patients questionnaire that asked attacks, use alternative treatments. mean Body Mass Index 27 +/- 4.0 kg/m(2), although change diet had been advised most patients,...

This study reports a straightforward but very effective method to produce nanocomposite hydrogels for targeted drug delivery system. An organic network containing both hydrophilic and hydrophobic components was obtained using thiol‐ene cross‐linking. Magnetite nanoparticles (MNPs) were synthesized by chemical co‐precipitation. The surface of the MNPs modified with allyl groups avoid agglomeration. Composite prepared addition hydrogel formulation at different ratios. composite investigated...

UV-cured epoxy-based polymeric film was prepared from glycidyl methacrylate, trimethylolpropane triacrylate, and poly(ethylene glycol) methylether acrylate. 2-hydroxy-2- methylpropiophenone used as photo initiator. Covalent binding through epoxy groups employed to immobilize β-galactosidase Escherichia coli onto this film, immobilization conditions were optimized by the response surface methodology. ATR-Fourier transform infrared (FTIR) scanning electron microscopy (SEM) analysis carried out...